{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T03:40:39Z","timestamp":1709869239993},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"728","license":[{"start":{"date-parts":[[1986,6,1]],"date-time":"1986-06-01T00:00:00Z","timestamp":517968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,6,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The results of indium-111 tropolonate leucocyte scintigraphy in 105 patients with known inflammatory bowel disease are reviewed. Scintigraphy is as sensitive as radiology in detecting and assessing the extent of active colonic disease, and probably more sensitive in assessing small bowel disease. In a further 40 patients scintigraphy was successfully used as a screening test to identify, or exclude, bowel inflammation in patients with gastrointestinal symptoms. Scintigraphy has advantages over barium studies, being safe, non-invasive, more sensitive than small bowel radiology and giving additional information such as the bowel identification of intra-abdominal abscesses. The time required to label the leucocytes (about 2 hours) and the higher unit cost, unless many scintigrams are performed, are disadvantages.<\/jats:p>","DOI":"10.1136\/pgmj.62.728.457","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T20:58:16Z","timestamp":1230584296000},"page":"457-462","source":"Crossref","is-referenced-by-count":12,"title":["Indium-111 leucocyte scintigraphy in the investigation and management of inflammatory bowel disease"],"prefix":"10.1093","volume":"62","author":[{"given":"K J","family":"Fotherby","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Addenbrooke's Hospital , Cambridge CB2 2QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E P","family":"Wraight","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Addenbrooke's Hospital , Cambridge CB2 2QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Garforth","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Addenbrooke's Hospital , Cambridge CB2 2QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J O","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Addenbrooke's Hospital , Cambridge CB2 2QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,6,1]]},"reference":[{"key":"ref_1","author":"JONES, A.L.U.N.; V., D.I.C.K.I.N.S.O.N.; J., R.; WORKMAN, E.; WILSON, A.J.; FREEMAN, A.H.; HUNTER, J.O.","year":"1985","unstructured":"ALUN JONES, V., DICKINSON, R.J., WORKMAN, E., WILSON, A.J., FREEMAN, A.H. & HUNTER, J.O. (1985)."},{"key":"ref_2","first-page":"463","article-title":"Differentiation between abscess formation and active Crohn's disease using indium-l I labelled leucocyte gamma imaging","volume":"24","author":"AMBROSE, N.S.; GOLDMAN, M.; HAWKER, R.J.; DROK, Z.; KEIGHLEY, M.R.B.; McCOLLUM, C.N.","year":"1983","unstructured":"AMBROSE, N.S., GOLDMAN, M., HAWKER, R.J., DROK, Z., KEIGHLEY, M.R.B. & McCOLLUM, C.N. (1983). Differentiation between abscess formation and active Crohn's disease using indium-l I labelled leucocyte gamma imaging. 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Gut, 26, 955.","journal-title":"Gut"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/S0016-5085(83)80138-3","article-title":"Location and activity of ulcerative and Crohn's colitis by indium111 leucocyte scan","volume":"84","author":"STEIN, D.T.; GRAY, G.M.; GREGORY, P.B.; ANDERSON, M.; GOODWIN, D.A.; McDOUGALL, I.R.","year":"1983","unstructured":"STEIN, D.T., GRAY, G.M., GREGORY, P.B., ANDERSON, M., GOODWIN, D.A. & McDOUGALL, I.R. (1983a). Location and activity of ulcerative and Crohn's colitis by indium111 leucocyte scan. Gastroenterology, 84, 388.","journal-title":"Gastroenterology"},{"key":"ref_15","first-page":"1321","article-title":"The indium-i 11 WBC scan as a detector of bowel disease","volume":"84","author":"STEIN, D.T.; GOODWIN, D.A.; McDOUGALL, I.R.","year":"1983","unstructured":"STEIN, D.T., GOODWIN, D.A. & McDOUGALL, I.R. (1983b). The indium-i 11 WBC scan as a detector of bowel disease. 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