{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T06:10:57Z","timestamp":1683267057085},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"735","license":[{"start":{"date-parts":[[1987,1,1]],"date-time":"1987-01-01T00:00:00Z","timestamp":536457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We report a case of prolonged loss of consciousness due to hypoglycaemia following ethanol abuse in a non-diabetic. The patient also reported symptoms compatible with hypoglycaemia following heavy manual work. Further investigations revealed a pancreatic insulinoma, which was successfully removed surgically. The patient remains asymptomatic 18 months later, despite occasional episodes of ethanol abuse. This case illustrates how heavy exercise and\/or alcohol abuse can aggravate spontaneous hypoglycaemia.<\/jats:p>","DOI":"10.1136\/pgmj.63.735.39","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:05:27Z","timestamp":1230584727000},"page":"39-40","source":"Crossref","is-referenced-by-count":0,"title":["Insulinoma presenting as alcoholic stupor"],"prefix":"10.1093","volume":"63","author":[{"given":"P","family":"Dandona","sequence":"first","affiliation":[{"name":"Metabolic Unit, Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V A","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Metabolic Unit, Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D P","family":"Mikhailidis","sequence":"additional","affiliation":[{"name":"Metabolic Unit, Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R K","family":"Menon","sequence":"additional","affiliation":[{"name":"Metabolic Unit, Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine , Pond Street, London NW3 2QG"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1987,1,1]]},"reference":[{"key":"ref_1","first-page":"867","volume-title":"Joslin's Diabetes MellitusLea and Febiger, Philadelphia","author":"Smith, R.J.; Marble, A.; Krall, L.P.; Bradley, R.F.; Christleib, A.","year":"1984","unstructured":"Smith, R.J., Marble, A., Krall, L.P., Bradley, R.F., Christleib, A.R. & Soeldner, J.S. (eds) In Joslin's Diabetes Mellitus, 12th Edition. Lea and Febiger, Philadelphia 1984, 867-881.","edition":"12"},{"issue":"206","key":"ref_2","first-page":"575","article-title":"Irreversible hypoglycaemia","volume":"1968","author":"Arky, R.A.; Venerbrants, E.; Abrahamson, E.A.","unstructured":"Arky, R.A., Venerbrants, E. & Abrahamson, E.A. Irreversible hypoglycaemia. JAMA 1968, 206: 575-578.","journal-title":"JAMA"},{"issue":"3","key":"ref_3","first-page":"43","article-title":"Brain damage following hypoglycaemia in alcoholic diabetics","volume":"1986","author":"Khaw, K.; Cassar, J.","unstructured":"Khaw, K. & Cassar, J. Brain damage following hypoglycaemia in alcoholic diabetics. Pract Diab 1986, 3: 43.","journal-title":"Pract Diab"},{"issue":"289","key":"ref_4","first-page":"225","article-title":"Deaths and paradoxes after intentional insulin overdose","volume":"1984","author":"Critchley, J.A.J.H.; Proudfoot, A.T.; Boyd, S.G.; Campbell, I.W.; Brown, N.S.; Gordon, A.","unstructured":"Critchley, J.A.J.H., Proudfoot, A.T., Boyd, S.G., Campbell, I.W., Brown, N.S. & Gordon, A. Deaths and paradoxes after intentional insulin overdose. Br Med J 1984, 289: 225.","journal-title":"Br Med J"},{"issue":"112","key":"ref_5","first-page":"117","article-title":"Inhibition ofhepatic gluconeogenesis by ethanol","volume":"1969","author":"Krebs, H.A.; Freedland, R.A.; Heurs, R.; Stubbs, M.","unstructured":"Krebs, H.A., Freedland, R.A., Heurs, R. & Stubbs, M. Inhibition ofhepatic gluconeogenesis by ethanol. Biochem J 1969, 112: 117-124.","journal-title":"Biochem J"},{"issue":"61","key":"ref_6","first-page":"941","article-title":"Ethanol decreases glucose utilisation in healthy man","volume":"1985","author":"Yki-Jarvinen, H.; Nikkila, E.A.","unstructured":"Yki-Jarvinen, H. & Nikkila, E.A. Ethanol decreases glucose utilisation in healthy man. J Clin Endocrinol Metab 1985, 61: 941-945.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_7","first-page":"171","article-title":"Ethanol and its metabolites are potent inhibitors of insulin action of adipocyte metabolism","volume":"133","author":"Lomeo, F.; Khokher, M.A.; Dandona, P.","year":"1984","unstructured":"Lomeo, F., Khokher, M.A. & Dandona, P. Ethanol and its metabolites are potent inhibitors of insulin action of adipocyte metabolism. Diabetes 1984, 133: 171A (Abstract).","journal-title":"Diabetes"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1056\/NEJM198204153061503","article-title":"Hypoglycaemia during prolonged exercise in normal men","volume":"306","author":"Felig, P.; Cherif, A.; Manigawa, A.; Wahren, J.","year":"1982","unstructured":"Felig, P., Cherif, A., Manigawa, A. & Wahren, J. Hypoglycaemia during prolonged exercise in normal men. N Engl J Med 1982, 306: 895-900.","journal-title":"N Engl J Med"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/S0140-6736(77)91321-6","article-title":"Lunchtime gin and tonic a cause of reactive hypoglycaemia","volume":"i:","author":"O'Keefe, S.J.; Marks, V.","year":"1977","unstructured":"O'Keefe, S.J., Marks, V. Lunchtime gin and tonic a cause of reactive hypoglycaemia. Lancet 1977, i: 1286-1288.","journal-title":"Lancet"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/63\/735\/39\/50079688\/postgradmedj-63-39.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/63\/735\/39\/50079688\/postgradmedj-63-39.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T05:56:35Z","timestamp":1683266195000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/63\/735\/39\/7047127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1,1]]},"references-count":9,"journal-issue":{"issue":"735","published-online":{"date-parts":[[1987,1,1]]},"published-print":{"date-parts":[[1987,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.63.735.39","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1987,1]]},"published":{"date-parts":[[1987,1,1]]}}}