{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T05:04:31Z","timestamp":1755925471973},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"743","license":[{"start":{"date-parts":[[1987,9,1]],"date-time":"1987-09-01T00:00:00Z","timestamp":557452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,9,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A case of the \u2018milk alkali syndrome\u2019 associated with grossly elevated levels of amino terminal parathyroid hormone is described. The hypercalcaemia (calcium 4.09 mmol\/l) and hyperparathyroidism settled on conservative measures. Factors in the milk alkali syndrome which might stimulate the release of parathyroid hormone include parathyroid gland hyperplasia secondary to suppression of ionized calcium, alteration in sensitivity of calcium receptors on the cells of the parathyroid glands, the stimulation of an intermittent alkaline tide in the blood and the high intake of phosphate and bicarbonate. We suggest that high levels of parathyroid hormone in the milk alkali syndrome may be appropriate rather than paradoxical.<\/jats:p>","DOI":"10.1136\/pgmj.63.743.789","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:05:27Z","timestamp":1230584727000},"page":"789-792","source":"Crossref","is-referenced-by-count":5,"title":["Raised parathyroid hormone levels in the milk alkali syndrome: an appropriate response?"],"prefix":"10.1093","volume":"63","author":[{"given":"D W","family":"Bullimore","sequence":"first","affiliation":[{"name":"St. James\u2019s Hospital , Leeds LS9 7TF , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K J","family":"Miloszewski","sequence":"additional","affiliation":[{"name":"St. James\u2019s Hospital , Leeds LS9 7TF , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1987,9,1]]},"reference":[{"issue":"64","key":"ref_1","first-page":"1625","article-title":"Gastric and duodenal ulcer; medical cure by an efficient removal of gastric juice corrosion","volume":"1915","author":"Sippy, B.W.","unstructured":"Sippy, B.W. Gastric and duodenal ulcer; medical cure by an efficient removal of gastric juice corrosion. JAMA 1915, 64: 1625-1630.","journal-title":"JAMA"},{"key":"ref_2","first-page":"31","article-title":"Toxic manifestations following the alkaline treatment of peptic ulcer","volume":"1923","author":"Hardt, L.L.; Rivers, A.B.","unstructured":"Hardt, L.L. & Rivers, A.B. Toxic manifestations following the alkaline treatment of peptic ulcer. Arch Intern Med 1923. 31: 171-180.","journal-title":"Arch Intern Med"},{"issue":"240","key":"ref_3","first-page":"787","article-title":"Hypercalcaemia without hypercalcuria or hypophosphataemia, calcinosis and renal insufficiency. A syndrome following prolonged intake of milk and alkali","volume":"1949","author":"Burnett, C.H.; Commons, R.R.; Albright, F.; Howard, J.E.","unstructured":"Burnett, C.H., Commons, R.R., Albright, F. & Howard, J.E. Hypercalcaemia without hypercalcuria or hypophosphataemia, calcinosis and renal insufficiency. A syndrome following prolonged intake of milk and alkali. N Engl J Med 1949, 240: 787-794.","journal-title":"N Engl J Med"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1056\/NEJM195403182501102","article-title":"Hyperparathyroidism with renal insufficiency. Report of a case confused with the 'Burnett Syndrome'","volume":"250","author":"Carpenter, H.M.; Paulter, E.E.","year":"1954","unstructured":"Carpenter, H.M. & Paulter, E.E. Hyperparathyroidism with renal insufficiency. Report of a case confused with the 'Burnett Syndrome'. N Engl J Med 1954, 250: 453-456.","journal-title":"N Engl J Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1056\/NEJM195412232512601","article-title":"Differentiation of hyperparathyroidism and the milk-alkali (Burnett) syndrome","volume":"251","author":"Kyle, L.H.","year":"1954","unstructured":"Kyle, L.H. Differentiation of hyperparathyroidism and the milk-alkali (Burnett) syndrome. 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