{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:48:41Z","timestamp":1761518921668},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"746","license":[{"start":{"date-parts":[[1987,12,1]],"date-time":"1987-12-01T00:00:00Z","timestamp":565315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,12,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A patient is described in whom the presenting feature of hypopituitarism was the development of palmar xanthomata associated with type III hyperlipoproteinaemia. Treatment of her secondary hypothyroidism with thyroxine caused resolution of the xanthomata and hyperlipidaemia, but the underlying compositional abnormality of the lipoproteins could still be observed.<\/jats:p>","DOI":"10.1136\/pgmj.63.746.1099","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:05:27Z","timestamp":1230584727000},"page":"1099-1100","source":"Crossref","is-referenced-by-count":3,"title":["Sheehan\u2019s syndrome presenting with type III hyperlipoproteinaemia"],"prefix":"10.1093","volume":"63","author":[{"given":"D","family":"Carr","sequence":"first","affiliation":[{"name":"North Tees General Hospital , Hardwick, Stockton-on-Tees, Cleveland, TS19 8PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H M","family":"Thornes","sequence":"additional","affiliation":[{"name":"North Tees General Hospital , Hardwick, Stockton-on-Tees, Cleveland, TS19 8PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A C","family":"Rutter","sequence":"additional","affiliation":[{"name":"North Tees General Hospital , Hardwick, Stockton-on-Tees, Cleveland, TS19 8PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R D","family":"Finney","sequence":"additional","affiliation":[{"name":"North Tees General Hospital , Hardwick, Stockton-on-Tees, Cleveland, TS19 8PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P R","family":"Turner","sequence":"additional","affiliation":[{"name":"Department of Chemical Pathology and Metabolic Disorders, St. Thomas\u2019 Hospital , London SE1 , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1987,12,1]]},"reference":[{"issue":"43","key":"ref_1","first-page":"891","article-title":"Classification of hyperlipidaemias and hyperlipoproteinaemias","volume":"1970","author":"Beaumont, J.L.; Carson, L.A.; Cooper, G.R.; Fejfar, Z.; Fredrickson, D.S.; Strasser, T.","unstructured":"Beaumont, J.L., Carson, L.A., Cooper, G.R., Fejfar, Z., Fredrickson, D.S. & Strasser, T. Classification of hyperlipidaemias and hyperlipoproteinaemias. Bull WHO 1970, 43: 891.","journal-title":"Bull WHO"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/0026-0495(72)90031-5","article-title":"Abnormal lipid composition of very low density lipoprotein in diagnosis of broad-beta disease (type III hyperlipoproteinaemia)","volume":"21","author":"Hazzard, W.R.; Porte, Jr., D.; Bierman, E.L.","year":"1972","unstructured":"Hazzard, W.R., Porte, D., Jr. & Bierman, E.L. Abnormal lipid composition of very low density lipoprotein in diagnosis of broad-beta disease (type III hyperlipoproteinaemia). Metabolism 1972, 21: 1009-1019.","journal-title":"Metabolism"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/269604a0","article-title":"Polymorphism of apolipoprotein E and occurrence of dysbetalipoproteinaemia in man","volume":"269","author":"Utermann, G.; Hees, M.; Steinmetz, A.","year":"1977","unstructured":"Utermann, G., Hees, M. & Steinmetz, A. Polymorphism of apolipoprotein E and occurrence of dysbetalipoproteinaemia in man. Nature 1977, 269: 604-607.","journal-title":"Nature"},{"issue":"15","key":"ref_4","first-page":"100","article-title":"Plasma apolipoprotein B metabolism in familial type III dysbetalipoproteinaemia","volume":"1985","author":"Turner, P.R.; Cortese, C.; Wooton, R.; Marenah, C.; Miller, N.E.; Lewis, B.","unstructured":"Turner, P.R., Cortese,C., Wooton,R., Marenah,C., Miller, N.E. & Lewis, B. Plasma apolipoprotein B metabolism in familial type III dysbetalipoproteinaemia. Eur J Clin Invest 1985, 15: 100-112.","journal-title":"Eur J Clin Invest"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1001\/archinte.1972.03650060018004","article-title":"Aggravation of broad-P disease (type 3 hyperlipoproteinaemia) by hypothyroidism","volume":"130","author":"Hazzard, W.R.; Bierman, E.L.","year":"1972","unstructured":"Hazzard, W.R. & Bierman, E.L. Aggravation of broad-P disease (type 3 hyperlipoproteinaemia) by hypothyroidism. Arch Intern Med 1972, 130: 822-828.","journal-title":"Arch Intern Med"},{"issue":"55","key":"ref_6","first-page":"640","article-title":"Late appearance of hyperlipemia in hypopituitarism","volume":"1961","author":"Jacobs, D.R.; Krieger, D.T.; Charles, R.N.","unstructured":"Jacobs, D.R., Krieger,D.T. & Charles, R.N. Late appearance of hyperlipemia in hypopituitarism. Ann Intern Med 1961, 55: 640-646.","journal-title":"Ann Intern Med"},{"issue":"16","key":"ref_7","first-page":"1106","article-title":"Serum lipids in diseases ofthe pituitary","volume":"1967","author":"Summers, V.K.; Hipkin, L.J.; Davis, J.C.","unstructured":"Summers, V.K., Hipkin, L.J. & Davis, J.C. Serum lipids in diseases ofthe pituitary. Metabolism 1967,16:1106-1113.","journal-title":"Metabolism"},{"issue":"110","key":"ref_8","first-page":"456","article-title":"Hyperlipidaemia in patients with hypopituitarism","volume":"1985","author":"Ishibashi, S.; Murase, T.; Yamada, N.; Tanaka, K.; Takaku, F.; Sato, K.","unstructured":"Ishibashi, S., Murase, T., Yamada, N., Tanaka, K., Takaku, F. & Sato, K. Hyperlipidaemia in patients with hypopituitarism. Acta Endocrinol 1985, 110: 456-460.","journal-title":"Acta Endocrinol"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/63\/746\/1099\/50080918\/postgradmedj-63-1099.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/63\/746\/1099\/50080918\/postgradmedj-63-1099.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T04:51:25Z","timestamp":1683262285000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/63\/746\/1099\/7047280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,12,1]]},"references-count":8,"journal-issue":{"issue":"746","published-online":{"date-parts":[[1987,12,1]]},"published-print":{"date-parts":[[1987,12,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.63.746.1099","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1987,12]]},"published":{"date-parts":[[1987,12,1]]}}}