{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T22:18:02Z","timestamp":1781734682985,"version":"3.54.5"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"749","license":[{"start":{"date-parts":[[1988,3,1]],"date-time":"1988-03-01T00:00:00Z","timestamp":573177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Fever is a common clinical manifestation of inflammatory processes of the thyroid and thyroid crisis. On the other hand, fever alone as a presenting symptom of thyrotoxicosis, without other manifestations, is extremely rare. A female patient is described in whom fever persisted for two months prior to hospitalization, but without clinical symptoms or signs to lead to suspicion of thyroid disease. After exhaustive investigation it was found that the patient was suffering from hyperthyroidism. Fever disappeared gradually on antithyroid therapy, recurred when the drugs were withdrawn for a rechallenge trial, and cleared up again after renewal. Four other cases of persistent fever as a presenting symptom of hyperthyroidism were found on a review of previous publications. Thyrotoxicosis should, therefore, be included in the differential diagnosis of pyrexia of unknown origin.<\/jats:p>","DOI":"10.1136\/pgmj.64.749.209","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:05:27Z","timestamp":1230584727000},"page":"209-212","source":"Crossref","is-referenced-by-count":11,"title":["Graves\u2019 disease presenting as pyrexia of unknown origin"],"prefix":"10.1093","volume":"64","author":[{"given":"Y","family":"Shaked","sequence":"first","affiliation":[{"name":"Rusinow Department of Internal Medicine C , Tel-Aviv University , Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Samra","sequence":"additional","affiliation":[{"name":"Rusinow Department of Internal Medicine C , Tel-Aviv University , Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S T","family":"Zwas","sequence":"additional","affiliation":[{"name":"Institute of Nuclear Medicine, the Chaim Sheba Medical Center, Tel-Hashomer and Sackler School of Medicine , Tel-Aviv University , Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1988,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1001\/archinte.1979.03630480009004","volume":"131","author":"Phair, J.P.","year":"1979","unstructured":"Phair, J.P. Fever (Editorial). Arch Intern Med 1979, 131: 1219.","journal-title":"Fever (Editorial). Arch Intern Med"},{"key":"ref_2","first-page":"12251228","volume":"131","author":"Musher, D.M.; Fainstein, V.; Young, E.J.; Pruett, T.L.","year":"1979","unstructured":"Musher, D.M., Fainstein, V., Young, E.J. & Pruett, T.L. Fever patterns. Arch Intern Med 1979, 131: 12251228.","journal-title":"Fever patterns. Arch Intern Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"230","DOI":"10.7326\/0003-4819-90-2-230","article-title":"Factitious fever and self-induced infection: a report on 32 cases and review of the literature","volume":"90","author":"Adnan, R.P.; Fauci, A.S.; Dale, D.C.","year":"1979","unstructured":"Adnan, R.P., Fauci, A.S., Dale, D.C. et al. Factitious fever and self-induced infection: a report on 32 cases and review of the literature. 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