{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T11:56:54Z","timestamp":1721735814918},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"760","license":[{"start":{"date-parts":[[1989,2,1]],"date-time":"1989-02-01T00:00:00Z","timestamp":602294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1989,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 58 year old woman, with dermatitis herpetiformis was found to have Hodgkin\u2019s disease following the discovery of an abdominal mass and splenomegaly. Combination chemotherapy was given. Although the abdominal mass and systemic symptoms resolved, the splenomegaly did not and the patient developed severe prolonged anaemia and pancytopaenia. Splenectomy resulted in a complete reversal of the haematological abnormalities. Histopathological examination of the spleen revealed fungal granulomas of Candida albicans. No residual Hodgkin\u2019s disease was found. The patient thus had hypersplenism due to fungal granulomas in the spleen. This form of presentation of fungal granuloma is very rare and resulted in delay in diagnosis and considerable morbidity to the patient.<\/jats:p>","DOI":"10.1136\/pgmj.65.760.83","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:05:27Z","timestamp":1230584727000},"page":"83-85","source":"Crossref","is-referenced-by-count":4,"title":["Hypersplenism due to fungal infection of spleen in a successfully treated patient with Hodgkin\u2019s disease"],"prefix":"10.1093","volume":"65","author":[{"given":"V","family":"Raina","sequence":"first","affiliation":[{"name":"Departments of Medical Oncology , Glasgow, G4 OSF , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P T","family":"Young","sequence":"additional","affiliation":[{"name":"Departments of Medical Oncology , Glasgow, G4 OSF , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A K","family":"Foulis","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Royal Infirmary , Glasgow, G4 OSF , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Soukop","sequence":"additional","affiliation":[{"name":"Departments of Medical Oncology , Glasgow, G4 OSF , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1989,2,1]]},"reference":[{"key":"ref_1","first-page":"20","article-title":"Systemic candidiasis in cancer patients","author":"Maksymiuk, A.W.; Thongprasert, S.; Hopffer, R.; Luna, M.; Fainstein, V.; Bodey, G.","year":"1984","unstructured":"Maksymiuk, A.W., Thongprasert, S., Hopffer, R., Luna, M., Fainstein, V. & Bodey, G. Systemic candidiasis in cancer patients. Am J Med 1984, 20-27.","journal-title":"Am J Med"},{"key":"ref_2","first-page":"50","article-title":"In: Candida and Candidiasis","author":"Odds, F.C.","year":"1970","unstructured":"Odds, F.C. In: Candida and Candidiasis. University Park Press, Baltimore, 1970, pp. 50-74."},{"key":"ref_3","first-page":"349","article-title":"Immunodiffusion and agglutination tests for candida in patients with neoplastic disease: inconsistent correlation of results with invasive infection","volume":"179","author":"Felice, G.; Yu, B.; Armstrong, D.","year":"1977","unstructured":"Felice, G., Yu, B. & Armstrong, D. Immunodiffusion and agglutination tests for candida in patients with neoplastic disease: inconsistent correlation of results with invasive infection. J Infect Dis 1977, 179: 349-352.","journal-title":"J Infect Dis"},{"issue":"24","key":"ref_4","first-page":"417","article-title":"Hypersplenism due to disseminated candidiasis in a patient with acute leukaemia","volume":"1969","author":"Bodey, G.P.; De Jongh, D.; Isassi, A.; Freireich, E.J.","unstructured":"Bodey, G.P., De Jongh, D., Isassi, A. & Freireich, E.J. Hypersplenism due to disseminated candidiasis in a patient with acute leukaemia. Cancer 1969, 24; 417-420.","journal-title":"Cancer"},{"key":"ref_5","first-page":"604","article-title":"Candidal abscess of the spleen in patients with acute leukaemia","volume":"181","author":"Page, C.P.; Coltman, C.A.; Robertson, H.W.; Nelson, E.A.","year":"1980","unstructured":"Page, C.P., Coltman, C.A., Robertson, H.W. & Nelson, E.A. Candidal abscess of the spleen in patients with acute leukaemia. Surg Gynecol Obstet 1980, 181: 604-608.","journal-title":"Surg Gynecol Obstet"},{"key":"ref_6","first-page":"144","article-title":"Fungal splenic abscess","volume":"1984","author":"Johnson, J.D.; Raff, M.J.","year":"1987","unstructured":"Johnson, J.D. & Raff, M.J. Fungal splenic abscess. Arch Intern Med 1984, 144: 1987-1993.","journal-title":"Arch Intern Med"},{"issue":"4","key":"ref_7","first-page":"129","article-title":"Diagnosis and treatment of fungal infections in patients with haematological malignancies","volume":"1986","author":"Radaelli, F.; Cortelezzi, A.; Zocchi, D.","unstructured":"Radaelli, F., Cortelezzi, A., Zocchi, D. et al. Diagnosis and treatment of fungal infections in patients with haematological malignancies. Haematol Oncol 1986, 4: 129-134.","journal-title":"Haematol Oncol"},{"key":"ref_8","first-page":"18","article-title":"Candida infections; clinical and pathological correlations in 168 consecutive autopsy-proven cases","volume-title":"cancer patients. Proc Am Soc Clin Oncol","author":"Brereton, H.D.; Ihde, D.; Levine, A.S.; Young, R.C.","year":"1979","unstructured":"Brereton, H.D., Ihde, D., Levine, A.S. & Young, R.C. Candida infections; clinical and pathological correlations in 168 consecutive autopsy-proven cases in cancer patients. Proc Am Soc Clin Oncol 1979, 18-19."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/65\/760\/83\/49243798\/postgradmedj-65-83.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/65\/760\/83\/49243798\/postgradmedj-65-83.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T18:01:38Z","timestamp":1681754498000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/65\/760\/83\/7044291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,2,1]]},"references-count":8,"journal-issue":{"issue":"760","published-online":{"date-parts":[[1989,2,1]]},"published-print":{"date-parts":[[1989,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.65.760.83","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1989,2]]},"published":{"date-parts":[[1989,2,1]]}}}