{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:31:53Z","timestamp":1785817913379,"version":"3.56.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"772","license":[{"start":{"date-parts":[[1990,2,1]],"date-time":"1990-02-01T00:00:00Z","timestamp":633830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1990,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 30 year old male patient with thyrotoxic crisis presenting as status epilepticus is reported. The aetiology, manifestations and management of this medical emergency are discussed. The importance of prompt, vigorous and comprehensive treatment of thyrotoxic crisis is emphasized. Rapid control of hyperthyroidism as well as other supportive measures are essential if the high fatality rate is to be reduced. Comprehensive management reduces mortality from 90% to 20%.<\/jats:p>","DOI":"10.1136\/pgmj.66.772.150","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"150-152","source":"Crossref","is-referenced-by-count":23,"title":["Thyrotoxic crisis presenting as status epilepticus"],"prefix":"10.1093","volume":"66","author":[{"given":"A F","family":"Safe","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Biochemistry, Gwynedd District General Hospital , Bangor, Gwynedd LL57 2PW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K D","family":"Griffiths","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Biochemistry, Gwynedd District General Hospital , Bangor, Gwynedd LL57 2PW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R T","family":"Maxwell","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Biochemistry, Gwynedd District General Hospital , Bangor, Gwynedd LL57 2PW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1990,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1056\/NEJM197412262912607","article-title":"Thyroid storm and its management","volume":"29","author":"Mackin, J.F.; Canary, J.J.; Pittman, C.S.","year":"1974","unstructured":"Mackin, J.F., Canary, J.J. & Pittman, C.S. Thyroid storm and its management. N Engl J Med 1974, 29: 1396-1398.","journal-title":"N Engl J Med"},{"issue":"52","key":"ref_2","first-page":"626","article-title":"A clinical study of thyroid storm","volume":"1960","author":"Waldstein, S.S.; Soldki, S.J.; Kagamec, G.I.","unstructured":"Waldstein, S.S., Soldki, S.J., Kagamec, G.I. et al. A clinical study of thyroid storm. Ann Int Med 1960, 52: 626-642.","journal-title":"Ann Int Med"},{"key":"ref_3","first-page":"800","article-title":"Thyroid storm or crisis","author":"Ingbar, W.","year":"1978","unstructured":"Ingbar, W. Thyroid storm or crisis. In: Werner, S.C. & Ingbar, S.H. (eds) The Thyroid. Harper & Row, London, 1978, p. 800."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1210\/jcem-40-2-339","article-title":"Serum triiodothyroxine in thyroid storm","volume":"40","author":"Brooks, M.H.; Waldstein, S.S.; Bronsky, D.","year":"1975","unstructured":"Brooks, M.H., Waldstein, S.S. & Bronsky, D. Serum triiodothyroxine in thyroid storm. J Clin Endocrinol Metab 1975, 40: 339-341.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"694","DOI":"10.7326\/0003-4819-93-5-694","article-title":"Free thyroxine concentration in thyroid storm","volume":"93","author":"Brooks, M.H.; Waldstein, S.S.","year":"1980","unstructured":"Brooks, M.H. & Waldstein, S.S. Free thyroxine concentration in thyroid storm. Ann Intern Med 1980, 93: 694-697.","journal-title":"Ann Intern Med"},{"key":"ref_6","first-page":"263","article-title":"Propanolol does not prevent thyroid storm","volume":"206","author":"Erikssen, M.; Robenfield, S.; Garber, A.J.; Kohler, P.O.","year":"1977","unstructured":"Erikssen, M., Robenfield, S., Garber, A.J. & Kohler, P.O. Propanolol does not prevent thyroid storm. N Engl J Med 1977, 206: 263-264.","journal-title":"N Engl J Med"},{"issue":"220","key":"ref_7","first-page":"237","article-title":"Effect of betamethasone on serum iodothyronine and thyroid hormone binding proteins in Graves'","volume":"1986","author":"Gamotedt, A.; Jarnerot, G.; Kagedal, B.; Tegler, L.","unstructured":"Gamotedt, A., Jarnerot, G., Kagedal, B. & Tegler, L. Effect of betamethasone on serum iodothyronine and thyroid hormone binding proteins in Graves' disease. Acta Med Scand 1986, 220: 237-240.","journal-title":"disease. Acta Med Scand"},{"key":"ref_8","first-page":"614","article-title":"Diseases of thyroid","volume-title":"Harrison's Principles of Internal Medicine","author":"Ingbar, S.H.; Waeber, K.A.","year":"1983","unstructured":"Ingbar, S.H. & Waeber, K.A. Diseases of thyroid. In: Petersdorf, R.G., Adams, R.D., Brunswald, E. et al. (eds) Harrison's Principles of Internal Medicine. McGraw-Hill, New York, 1983, pp. 614-633."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1055\/s-0028-1093968","article-title":"Thyroxine elimination by peritoneal dialysis in experimental thyrotoxicosis","volume":"5","author":"Herrman, J.; Schmidtt, H.J.; Kruskemper, H.L.","year":"1973","unstructured":"Herrman, J., Schmidtt, H.J. & Kruskemper, H.L. Thyroxine elimination by peritoneal dialysis in experimental thyrotoxicosis. Horm Metab Res 1973, 5: 180-183.","journal-title":"Horm Metab Res"},{"issue":"12","key":"ref_10","first-page":"536","article-title":"Successful treatment of thyrotoxic crisis with plasma exchange","volume":"1984","author":"Tajiri, J.; Katsuya, H.; Kiyokama, T.; Urata, K.; Okamato, K.; Spimada, T.","unstructured":"Tajiri, J., Katsuya, H., Kiyokama, T., Urata, K., Okamato, K. & Spimada, T. Successful treatment of thyrotoxic crisis with plasma exchange. Crit Care Med 1984, 12: 536-537.","journal-title":"Crit Care Med"},{"key":"ref_11","first-page":"671","article-title":"Propanolol for thyroid storm","volume":"279","author":"Hellman, R.; Kelly, R.L.; Mason, W.D.","year":"1977","unstructured":"Hellman, R., Kelly, R.L. & Mason, W.D. Propanolol for thyroid storm. N Engl J Med 1977, 279: 671-672.","journal-title":"N Engl J Med"},{"key":"ref_12","first-page":"59","article-title":"Thyroid storm","volume-title":"Current Therapy in Endocrinology and Metabolism","author":"Robins, J.","year":"1985","unstructured":"Robins, J. Thyroid storm. In: Krieger, D.T. & Bardin, C.W. (eds) Current Therapy in Endocrinology and Metabolism. B.C. Decker Inc., Philadelphia, 1985, pp. 59-61."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/66\/772\/150\/50076822\/postgradmedj-66-150.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/66\/772\/150\/50076822\/postgradmedj-66-150.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T15:53:15Z","timestamp":1682697195000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/66\/772\/150\/7062022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,2,1]]},"references-count":12,"journal-issue":{"issue":"772","published-online":{"date-parts":[[1990,2,1]]},"published-print":{"date-parts":[[1990,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.66.772.150","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1990,2]]},"published":{"date-parts":[[1990,2,1]]}}}