{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:03:41Z","timestamp":1790805821352,"version":"4.1.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"779","license":[{"start":{"date-parts":[[1990,9,1]],"date-time":"1990-09-01T00:00:00Z","timestamp":652147200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1990,9,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>We describe a case of POEMS syndrome presenting with the recognized features of polyneuropathy, organomegaly, endocrine abnormalities, monoclonal protein, skin changes and anasarca. The patient was found to have both a solitary sclerotic plasmacytoma of the pelvis and evidence of Castleman's disease of lymph nodes. A number of unusual and unique features are also documented. Histological examination of affected skin demonstrated changes similar to urticaria pigmentosa including local oedema and mast cell infiltration. There was marked thrombocythaemia which has been seen in only one previous case and in addition the patient developed diffuse vascular calcification in the absence of recognized aetiological factors. Radiotherapy of the pelvic lesion and chemotherapy to control the myeloproliferative disorder gave rise to significant improvement in neuropathy. Control of anasarca required steroid therapy in addition to diuretics. The significance of these observations is discussed in relation to previous reports.<\/jats:p>","DOI":"10.1136\/pgmj.66.779.761","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"761-767","source":"Crossref","is-referenced-by-count":18,"title":["A case of POEMS syndrome associated with essential thrombocythaemia and dermal mastocytosis"],"prefix":"10.1093","volume":"66","author":[{"given":"A","family":"Jackson","sequence":"first","affiliation":[{"name":"Department of Haematology, University Hospital of South Manchester , Nell Lane, Withington, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I E","family":"Burton","sequence":"additional","affiliation":[{"name":"Department of Haematology, University Hospital of South Manchester , Nell Lane, Withington, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1990,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/00005792-198007000-00006","article-title":"Plasma cell neoplasia with polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes, the POEMS syndrome: report on two cases and a review of the literature","volume":"59","author":"Bardwick, P.A.; Zvaifler, N.J.; Gill, G.N.; Newman, D.; Greenway, G.D.; Resenick, K.L.","year":"1980","unstructured":"Bardwick, P.A., Zvaifler, N.J., Gill, G.N., Newman, D., Greenway, G.D. & Resenick, K.L. Plasma cell neoplasia with polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes, the POEMS syndrome: report on two cases and a review of the literature. Medicine (Baltimore) 1980, 59: 311-322.","journal-title":"Medicine (Baltimore)"},{"issue":"14","key":"ref_2","first-page":"247","article-title":"Myelom und nervensystem: Uber eine bisher nicht beschreibener mit eigen tumlichen hautveranderungen einhergehende polyneuritis bei einem plasmazellaren myelosis des sternums","volume":"1938","author":"Scheinker, M.","unstructured":"Scheinker, M. Myelom und nervensystem: Uber eine bisher nicht beschreibener mit eigen tumlichen hautveranderungen einhergehende polyneuritis bei einem plasmazellaren myelosis des sternums. Z Neurol 1938, 14: 247-273.","journal-title":"Z Neurol"},{"issue":"2","key":"ref_3","first-page":"802","article-title":"Peripheral neuritis in myelomatosis","volume":"1956","author":"Crow, R.S.","unstructured":"Crow, R.S. Peripheral neuritis in myelomatosis. Br Med J 1956, 2: 802-804.","journal-title":"Br Med J"},{"issue":"9","key":"ref_4","first-page":"657","article-title":"Report of a case of solitary plasmacytoma in the abdomen presenting with polyneuropathy and endocrinological disorders","volume":"1969","author":"Fukase, M.; Kakimatsu, T.; Nishitana, H.; Naguchi, S.","unstructured":"Fukase, M., Kakimatsu, T., Nishitana, H. & Naguchi, S. Report of a case of solitary plasmacytoma in the abdomen presenting with polyneuropathy and endocrinological disorders. Clin Neurol (Tokyo) 1969, 9: 657-661.","journal-title":"Clin Neurol (Tokyo)"},{"key":"ref_5","series-title":"Topics in Haematology, Proceedings of the 16th International Congress of Haematology, Kyoto; Excerpta Medica","first-page":"454","article-title":"Plasma cell dyscrasia with polyneuropathy and endocrine disorder: review of 32 patients","author":"Takatsuki, K.; Uchiyama, T.; Sagawa, K.; Yodoi, J.","year":"1977","unstructured":"Takatsuki, K., Uchiyama, T., Sagawa, K. & Yodoi, J. Plasma cell dyscrasia with polyneuropathy and endocrine disorder: review of 32 patients. In: Seno, S., Takaku, F. & Irino, S. (eds). Topics in Haematology, Proceedings of the 16th International Congress of Haematology, Kyoto, 1977. Excerpta Medica, Amsterdam, 1977, pp. 454-457."},{"issue":"34","key":"ref_6","first-page":"712","article-title":"The CrowFukase syndrome a study of 102 cases in Japan","volume":"1984","author":"Nakanishi, T.; Sobue, I.; Toyokura, Y.","unstructured":"Nakanishi, T., Sobue, I., Toyokura, Y. et al. The CrowFukase syndrome a study of 102 cases in Japan. Neurology 1984, 34: 712-720.","journal-title":"Neurology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1212\/WNL.33.2.202","article-title":"Osteosclerotic myeloma and peripheral neuropathy","volume":"33","author":"Kelly, J.J.; Kyle, R.A.; Miles, J.M.; Dyck, P.J.D.","year":"1983","unstructured":"Kelly, J.J., Kyle, R.A., Miles, J.M. & Dyck, P.J.D. Osteosclerotic myeloma and peripheral neuropathy. Neurology 1983, 33: 202-210.","journal-title":"Neurology"},{"key":"ref_8","first-page":"219","article-title":"On the aetiology of PEP syndrome (A peculiar progressive polyneuritis associated with pigmentation, oedema, plasma cell dyscrasia)","volume":"32","author":"Saikawa, S.","year":"1980","unstructured":"Saikawa, S. On the aetiology of PEP syndrome (A peculiar progressive polyneuritis associated with pigmentation, oedema, plasma cell dyscrasia). MedJ Kagoshima Univ 1980, 32: 219-243.","journal-title":"MedJ Kagoshima Univ"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/00005792-198007000-00005","article-title":"Plasma cell neoplasia with peripheral neuropathy. A study of 5 cases and review of the literature","volume":"59","author":"Dreidger, H.; Pruzanski, W.","year":"1980","unstructured":"Dreidger, H. & Pruzanski, W. Plasma cell neoplasia with peripheral neuropathy. A study of 5 cases and review of the literature. Medicine (Baltimore) 1980, 59: 301-310.","journal-title":"Medicine (Baltimore)"},{"issue":"48","key":"ref_10","first-page":"845","article-title":"Solitary myeloma: clinical and prognostic features of a review of 114 cases","volume":"1981","author":"Bataille, R.; Sany, J.","unstructured":"Bataille, R. & Sany, J. Solitary myeloma: clinical and prognostic features of a review of 114 cases. Cancer 1981, 48: 845-851.","journal-title":"Cancer"},{"issue":"52","key":"ref_11","first-page":"757","article-title":"Multiple myeloma with osteosclerosis","volume":"1969","author":"Lowbeer, L.","unstructured":"Lowbeer, L. Multiple myeloma with osteosclerosis. Am J Clin Pathol 1969, 52: 757-768.","journal-title":"Am J Clin Pathol"},{"issue":"219","key":"ref_12","first-page":"377","article-title":"Osteoblastic lesions of unusual nature","volume":"1972","author":"Courey, R.U.","unstructured":"Courey, R.U. Osteoblastic lesions of unusual nature. JAMA 1972, 219: 377-388.","journal-title":"JAMA"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1177\/014107688207500714","article-title":"Plasma cell dyscrasia and polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes: the POEMS syndrome","volume":"75","author":"Solomons, R.E.B.; Gibbs, D.D.","year":"1982","unstructured":"Solomons, R.E.B. & Gibbs, D.D. Plasma cell dyscrasia and polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes: the POEMS syndrome. J R Soc Med 1982, 75: 553-555.","journal-title":"J R Soc Med"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1001\/archinte.1982.00340190191032","article-title":"Studies in a patient with an IgG-K M protein but no polyneuropathy","volume":"142","author":"Morrow, R.; Scheafer, E.J.; Huston, E.P.; Rosen, S.W.","year":"1982","unstructured":"Morrow, R., Scheafer, E.J., Huston, E.P. & Rosen, S.W. Studies in a patient with an IgG-K M protein but no polyneuropathy. Arch Int Med 1982, 142: 1231-1234.","journal-title":"Arch Int Med"},{"key":"ref_15","first-page":"27","article-title":"POEMS syndrome with neuroarthropathy and nodular regenerative hyperplasia of the liver","volume":"1984","author":"Zea-Mendosa, A.; Alonso-Ruiz, A.; Garcia-Vadillo, A.; Moreno-Caparros, A.; Beltran-Gutierrez, J.","unstructured":"Zea-Mendosa, A., Alonso-Ruiz, A., Garcia-Vadillo, A., Moreno-Caparros, A. & Beltran-Gutierrez, J. POEMS syndrome with neuroarthropathy and nodular regenerative hyperplasia of the liver. Arthritis Rheum 1984, 27: 1053-1057.","journal-title":"Arthritis Rheum"},{"issue":"142","key":"ref_16","first-page":"731","article-title":"Crow-Fukase syndrome (POEMS syndrome) and osseous mastocytosis secondary to Castlemans angiofollicular lymphoid hyperplasia","volume":"1986","author":"Lapresle, J.; Lacroix-Ciaudo, C.; Reynes, M.; Madoule, P.","unstructured":"Lapresle, J., Lacroix-Ciaudo, C., Reynes, M. & Madoule, P. Crow-Fukase syndrome (POEMS syndrome) and osseous mastocytosis secondary to Castlemans angiofollicular lymphoid hyperplasia. Rev Neurol (Paris) 1986, 142: 731-737.","journal-title":"Rev Neurol (Paris)"},{"key":"ref_17","first-page":"203","article-title":"Peripheral sensorimotor neuropathy associated with a localised myeloma","volume":"i:","author":"Rushton, D.I.","unstructured":"Rushton, D.I. Peripheral sensorimotor neuropathy associated with a localised myeloma. Br Med J 1965, i: 203-205.","journal-title":"Br Med J 1965"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1001\/archneur.1972.00490180043010","article-title":"Myeloma neuropathy: successful treatment of two patients and review of cases","volume":"27","author":"Davis, L.E.; Drachman, D.B.","year":"1972","unstructured":"Davis, L.E. & Drachman, D.B. Myeloma neuropathy: successful treatment of two patients and review of cases. Arch Neurol 1972, 27: 507-511.","journal-title":"Arch Neurol"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.0954-6820.1980.tb01167.x","article-title":"Osteosclerotic myeloma with polyneuropathy","volume":"208","author":"Reitan, J.B.; Pope, E.; Fossa, S.D.; Julsrael, O.J.; Slettnes, O.N.; Solheim, O.P.","year":"1980","unstructured":"Reitan, J.B., Pope, E., Fossa, S.D., Julsrael, O.J., Slettnes, O.N. & Solheim, O.P. Osteosclerotic myeloma with polyneuropathy. Acta Med Scand 1980, 208: 137-144.","journal-title":"Acta Med Scand"},{"issue":"48","key":"ref_20","first-page":"383","article-title":"Peripheral neuropathy and plasma cell neoplasias: a report of 10 cases","volume":"1981","author":"Delauche, M.C.; Clauvel, J.P.; Seligmann, M.","unstructured":"Delauche, M.C., Clauvel, J.P. & Seligmann, M. Peripheral neuropathy and plasma cell neoplasias: a report of 10 cases. Br J Haematol 1981, 48: 383-392.","journal-title":"Br J Haematol"},{"issue":"30","key":"ref_21","first-page":"432","article-title":"The relation between chronic polyneuropathy and osteosclerotic myeloma","volume":"1967","author":"Morley, J.B.; Schweiger, A.C.","unstructured":"Morley, J.B. & Schweiger, A.C. The relation between chronic polyneuropathy and osteosclerotic myeloma. J Neurol Neurosurg Psychiatry 1967, 30: 432-442.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"13","key":"ref_22","first-page":"366","article-title":"The clinical implications of monoclonal immunoglobulins","volume":"1986","author":"Farhangi, M.; Merlini, G.","unstructured":"Farhangi, M. & Merlini, G. The clinical implications of monoclonal immunoglobulins. Semin Oncol 1986, 13: 366-379.","journal-title":"Semin Oncol"},{"issue":"303","key":"ref_23","first-page":"618","article-title":"Plasma cell dyscrasia and peripheral neuropathy with a monoclonal antibody to peripheral nerve myelin","volume":"1980","author":"Latov, N.; Sherman, W.H.; Nemni, R.","unstructured":"Latov, N., Sherman, W.H., Nemni, R. et al. Plasma cell dyscrasia and peripheral neuropathy with a monoclonal antibody to peripheral nerve myelin. NEnglJ Med 1980,303: 618-621.","journal-title":"NEnglJ Med"},{"issue":"36","key":"ref_24","first-page":"75","article-title":"Monoclonal gammopathy and neuropathy: a myelin associated glycoprotein reactivity and clinical characteristics","volume":"1986","author":"Hafler, D.A.; Johnson, D.; Kelly, J.J.; Panitch, H.; Kyle, R.; Weiner, H.L.","unstructured":"Hafler, D.A., Johnson, D., Kelly, J.J., Panitch, H., Kyle, R. & Weiner, H.L. Monoclonal gammopathy and neuropathy: a myelin associated glycoprotein reactivity and clinical characteristics. Neurology 1986, 36: 75-78.","journal-title":"Neurology"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1001\/archderm.1987.01660250091026","article-title":"The skin changes in the Crow-Fukase (POEMS) syndrome. A case report","volume":"123","author":"Shelley, W.B.; Shelley, E.D.","year":"1987","unstructured":"Shelley, W.B. & Shelley, E.D. The skin changes in the Crow-Fukase (POEMS) syndrome. A case report. Arch Dermatol 1987, 123: 85-87.","journal-title":"Arch Dermatol"},{"issue":"59","key":"ref_26","first-page":"194","article-title":"The mastocytosis syndrome clinical and biological studies","volume":"1963","author":"Demis, D.J.","unstructured":"Demis, D.J. The mastocytosis syndrome clinical and biological studies. Ann Int Med 1963, 59: 194-206.","journal-title":"Ann Int Med"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1056\/NEJM197908303010903","article-title":"Oral disodium cromoglycate in the treatment of systemic mastocytosis","volume":"301","author":"Soter, N.A.; Austen, K.F.; Wasserman, S.I.","year":"1979","unstructured":"Soter, N.A., Austen, K.F. & Wasserman, S.I. Oral disodium cromoglycate in the treatment of systemic mastocytosis. N Engl J Med 1979, 301: 465-469.","journal-title":"N Engl J Med"},{"issue":"287","key":"ref_28","first-page":"138","article-title":"Case records of the Massachusetts","volume":"1972","author":"Castleman, B.; Scully, R.E.; McNealy, B.U.","unstructured":"Castleman, B., Scully, R.E. & McNealy, B.U. Case records of the Massachusetts General Hospital. NEnglJ Med 1972,287: 138-143.","journal-title":"General Hospital. NEnglJ Med"},{"issue":"12","key":"ref_29","first-page":"961","article-title":"Cutaneous angiomas in POEMS syndrome","volume":"1985","author":"Puig, M.; Moreno, A.; Domingo, P.; Llistosella, E.; De Moragas, M.","unstructured":"Puig, M., Moreno, A., Domingo, P., Llistosella, E. & De Moragas, M. Cutaneous angiomas in POEMS syndrome. J Am Acad Dermatol 1985, 12: 961-964.","journal-title":"J Am Acad Dermatol"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1001\/archinte.1977.03630240053018","article-title":"A unique multi system syndrome of unknown origin","volume":"137","author":"Meshkinpour, G.; Myung, C.G.; Kramer, L.S.","year":"1977","unstructured":"Meshkinpour, G., Myung, C.G. & Kramer, L.S. A unique multi system syndrome of unknown origin. Arch Int Med 1977, 137: 1719-1721.","journal-title":"Arch Int Med"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/1097-0142(19890315)63:6<1175::AID-CNCR2820630622>3.0.CO;2-4","article-title":"POEMS syndrome associated with polycythaemia vera","volume":"63","author":"Schultz, W.; Domenico, D.; S, Vand","year":"1989","unstructured":"Schultz, W., Domenico, D. & Vand S. POEMS syndrome associated with polycythaemia vera. Cancer 1989, 63:1175-1178.","journal-title":"Cancer"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/0002-9343(79)90800-3","article-title":"Thrombocytosis, coronary thrombosis and acute myocardial infarction","volume":"67","author":"Virmani, R.; Papousky, M.A.; Roberts, W.C.","year":"1979","unstructured":"Virmani, R., Papousky, M.A. & Roberts, W.C. Thrombocytosis, coronary thrombosis and acute myocardial infarction. Am J Med 1979, 67: 498-506.","journal-title":"Am J Med"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"271","DOI":"10.7326\/0003-4819-84-3-271","article-title":"Polyneuropathy and anasarca: evidence for a new connective tissue syndrome and vasculopathic contribution","volume":"84","author":"Trentham, D.E.; Masi, A.T.; Marker, H.W.","year":"1976","unstructured":"Trentham, D.E., Masi, A.T. & Marker, H.W. Polyneuropathy and anasarca: evidence for a new connective tissue syndrome and vasculopathic contribution. Ann Int Med 1976, 84: 271-274.","journal-title":"Ann Int Med"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/pgmj.56.656.427","article-title":"Plasma cell dyscrasia with polyneuritis and dermato-endocrine alterations. Report of a new case outside","volume":"56","author":"Moya-Mir, M.S.; Martin-Matin, F.; Barbadillo, R.; CuervasMons, V.; Martin-Jimenez, T.; Sanchez-Miro, I.","year":"1980","unstructured":"Moya-Mir, M.S., Martin-Matin, F., Barbadillo, R., CuervasMons, V., Martin-Jimenez, T. & Sanchez-Miro, I. Plasma cell dyscrasia with polyneuritis and dermato-endocrine alterations. Report of a new case outside Japan. Postgrad Med J 1980, 56: 427-430.","journal-title":"Japan. Postgrad Med J"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"490","DOI":"10.7326\/0003-4819-81-4-490","article-title":"Syndrome of plasma cell dyscrasia, polyneuropathy and endocrine disturbances","volume":"81","author":"Imawari, M.; Akatsuka, N.; Ishibashi, M.; Beppa, H.; Suzuki, H.; Yoshitashi, Y.","year":"1974","unstructured":"Imawari, M., Akatsuka, N., Ishibashi, M., Beppa, H., Suzuki, H. & Yoshitashi, Y. Syndrome of plasma cell dyscrasia, polyneuropathy and endocrine disturbances. Ann Int Med 1974, 81: 490-493.","journal-title":"Ann Int Med"},{"issue":"29","key":"ref_36","first-page":"286","article-title":"Light and electron microscopic findings in POEMS or Japanese multisystem syndrome","volume":"1986","author":"Semble, E.L.; Challa, V.R.; Holt, D.A.; Pisko, E.S.","unstructured":"Semble, E.L., Challa, V.R., Holt, D.A. & Pisko, E.S. Light and electron microscopic findings in POEMS or Japanese multisystem syndrome. Arthritis Rheum 1986, 29: 286-291.","journal-title":"Arthritis Rheum"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1136\/pgmj.58.686.786","article-title":"The Japanese plasma cell dyscrasia syndrome: case report and theory of pathogenesis","volume":"58","author":"Tobin, M.J.; Fitzgerald, M.X.","year":"1982","unstructured":"Tobin, M.J. & Fitzgerald, M.X. The Japanese plasma cell dyscrasia syndrome: case report and theory of pathogenesis. Postgrad Med J 1982, 58: 786-789.","journal-title":"Postgrad Med J"},{"key":"ref_38","first-page":"147","article-title":"Eruptive angiomata in malignant disease. Clin Exp Dermatol","volume":"3","author":"Pembroke, A.L.; Grice, K.; Levantine, A.V.; Warin, A.P.","year":"1978","unstructured":"Pembroke, A.L., Grice, K., Levantine, A.V. & Warin, A.P. Eruptive angiomata in malignant disease. Clin Exp Dermatol 1978, 3: 147-156."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1365-2133.1987.tb04933.x","article-title":"The skin changes of POEMS syndrome","volume":"117","author":"Ishikawa, O.; Nihei, Y.; Ishikawa, H.","year":"1987","unstructured":"Ishikawa, O., Nihei, Y. & Ishikawa, H. The skin changes of POEMS syndrome. Br J Dermatol 1987, 117: 523-526.","journal-title":"Br J Dermatol"},{"issue":"124","key":"ref_40","first-page":"695","article-title":"Cutaneous angiomas in POEMS syndrome. An ultrastructural and immunohistochemical study","volume":"1988","author":"Kanitakis, J.; Roger, H.; Soubrier, M.; Dubost, J.J.; Chouvet, B.; Souteyrand, P.","unstructured":"Kanitakis, J., Roger, H., Soubrier, M., Dubost, J.J., Chouvet, B. & Souteyrand, P. Cutaneous angiomas in POEMS syndrome. An ultrastructural and immunohistochemical study. Arch Dermatol 1988, 124: 695-698.","journal-title":"Arch Dermatol"},{"issue":"9","key":"ref_41","first-page":"822","article-title":"Localised mediastinal lymph node hyperplasia resembling thymoma","volume":"1956","author":"Castleman, B.; Iversen, L.; Menendez, V.P.","unstructured":"Castleman, B., Iversen, L. & Menendez, V.P. Localised mediastinal lymph node hyperplasia resembling thymoma. Cancer 1956, 9: 822-830.","journal-title":"Cancer"},{"key":"ref_42","first-page":"606","article-title":"Case records of the Massachusetts","volume":"316","author":"Scully, R.E.; Mark, E.J.; McNeely, W.F.; McNeely, B.U.","year":"1987","unstructured":"Scully, R.E., Mark, E.J., McNeely, W.F. & McNeely, B.U. Case records of the Massachusetts General Hospital. N Engl J Med 1987, 316: 606-618.","journal-title":"General Hospital. N Engl J Med"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/1097-0142(197203)29:3<670::AID-CNCR2820290321>3.0.CO;2-#","article-title":"Hyaline vascular and plasma cell types of giant lymph node hyperplasia of the mediastinum and other locations","volume":"29","author":"Keller, A.R.; Hockholzer, L.; Castleman, B.","year":"1972","unstructured":"Keller, A.R., Hockholzer, L. & Castleman, B. Hyaline vascular and plasma cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 1972, 29: 670-683.","journal-title":"Cancer"},{"issue":"6","key":"ref_44","first-page":"188","article-title":"Giant lymph node hyperplasia with osteoblastic bone lesions and the POEMS (Takatsuki's) syndrome","volume":"1985","author":"Bitter, M.A.; Komaiko, W.; Franklin, W.A.","unstructured":"Bitter, M.A., Komaiko, W. & Franklin, W.A. Giant lymph node hyperplasia with osteoblastic bone lesions and the POEMS (Takatsuki's) syndrome. Cancer 1985, 6:188-194.","journal-title":"Cancer"},{"issue":"58","key":"ref_45","first-page":"169","article-title":"Multicentric giant lymph node hyperplasia, pseudotumour cerebri, neuropathy and dysproteinaemia: A new clinicopathological entity","volume":"1981","author":"Sweet, D.L.; Variakojis, D.; Kluskens, L.F.","unstructured":"Sweet, D.L., Variakojis, D. & Kluskens, L.F. Multicentric giant lymph node hyperplasia, pseudotumour cerebri, neuropathy and dysproteinaemia: A new clinicopathological entity. Blood 1981, 58: 169a.","journal-title":"Blood"},{"key":"ref_46","first-page":"116","article-title":"endocrinopathy and skin changes in a case of solitary myeloma","volume":"1986","author":"Meier, C.; Reulecke, M.Kesselring; J.","unstructured":"Meier, C., Reulecke, M. Kesselring, J. et al. Polyneuropathy, organomegaly, endocrinopathy and skin changes in a case of solitary myeloma. Schweiz Med Wochenschr 1986, 116: 1326-1331.","journal-title":"Schweiz Med Wochenschr"},{"issue":"26","key":"ref_47","first-page":"2644","article-title":"Solitary plasmacytoma with polyneuritis and endocrine disturbance","volume":"1968","author":"Shimpo, S.","unstructured":"Shimpo, S. Solitary plasmacytoma with polyneuritis and endocrine disturbance. Jap J Clin Med 1968, 26: 2644-2656.","journal-title":"Jap J Clin Med"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1365-2133.1978.tb06184.x","article-title":"A new syndrome with pigmentation, scleroderma, gynaecomastia, Raynaud's phenomenon and peripheral neuropathy","volume":"99","author":"Saihan, E.M.; Burton, J.L.; Heaton, K.W.","year":"1978","unstructured":"Saihan, E.M., Burton, J.L. & Heaton, K.W. A new syndrome with pigmentation, scleroderma, gynaecomastia, Raynaud's phenomenon and peripheral neuropathy. Br J Dermatol 1978, 99: 437-440.","journal-title":"Br J Dermatol"},{"issue":"38","key":"ref_49","first-page":"614","article-title":"Specific antibody against neuroendocrine tissue in a case of POEMS syndrome with IgG gammopathy","volume":"1988","author":"Reulecke, M.; Dumas, M.; Meier, C.","unstructured":"Reulecke, M., Dumas, M. & Meier, C. Specific antibody against neuroendocrine tissue in a case of POEMS syndrome with IgG gammopathy. Neurology 1988, 38: 614-616.","journal-title":"Neurology"},{"issue":"84","key":"ref_50","first-page":"524","article-title":"POEMS syndrome presenting as systemic sclerosis. Clinical and pathological study of a case with microangiopathic glomerular lesions","volume":"1988","author":"Viard, J.P.; Lesavrl, L.H.; Roth, A.; Said, G.; Bach, J.F.","unstructured":"Viard, J.P., Lesavrl, L.H., Roth, A., Said, G. & Bach, J.F. POEMS syndrome presenting as systemic sclerosis. Clinical and pathological study of a case with microangiopathic glomerular lesions. Am J Med 1988, 84: 524-528.","journal-title":"Am J Med"},{"issue":"332","key":"ref_51","first-page":"83","article-title":"Autocrine generation and requirements of BSF-2\/IL-6 for multiple myelomas","volume":"1988","author":"Kawano, M.; Hirano, T.; Matsudo, T.; Taga, T.; Harri, Y.; Iwato, K.","unstructured":"Kawano, M., Hirano, T., Matsudo, T., Taga, T., Harri, Y., Iwato, K. et al. Autocrine generation and requirements of BSF-2\/IL-6 for multiple myelomas. Nature 1988,332:83-84.","journal-title":"Nature"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/S0140-6736(89)92874-2","article-title":"Peptide regulatory factors, Haemopoietic growth factors 2: clinical applications","volume":"i:","author":"Metcalf, D.","year":"1989","unstructured":"Metcalf, D. Peptide regulatory factors, Haemopoietic growth factors 2: clinical applications. Lancet 1989, i: 885-887.","journal-title":"Lancet"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/66\/779\/761\/50202865\/postgradmedj-66-761.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/66\/779\/761\/50202865\/postgradmedj-66-761.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T03:08:22Z","timestamp":1709867302000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/66\/779\/761\/7062188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,9,1]]},"references-count":52,"journal-issue":{"issue":"779","published-online":{"date-parts":[[1990,9,1]]},"published-print":{"date-parts":[[1990,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.66.779.761","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1990,9]]},"published":{"date-parts":[[1990,9,1]]}}}