{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:39:29Z","timestamp":1757702369637},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"782","license":[{"start":{"date-parts":[[1990,12,1]],"date-time":"1990-12-01T00:00:00Z","timestamp":660009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1990,12,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>It has been reported that bone density is increased in patients with treated hypoparathyroidism, though it is unclear whether this increase is attributable to the condition itself or to its treatment. We have recently investigated a 70 year old woman with untreated hypoparathyroidism from the time of thyroid surgery at the age of 29 years. Bone mineral content of the non-dominant distal forearm was 3.7 standard deviations above the mean normal value found in 23 healthy volunteers of comparable menopausal age, and was also above the mean normal value found in premenopausal women. The vertebral mineral density of her lumbar spine (measured by quantitative computed tomography) was 3.0 standard deviations above the mean normal value. These findings suggest that high bone density is a feature of hypoparathyroidism per se and that postmenopausal bone loss may be significantly attenuated in this condition.<\/jats:p>","DOI":"10.1136\/pgmj.66.782.1061","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"1061-1063","source":"Crossref","is-referenced-by-count":8,"title":["High peripheral and axial bone densities in a postmenopausal woman with untreated hypoparathyroidism"],"prefix":"10.1093","volume":"66","author":[{"given":"B","family":"Orr-Walker","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Auckland , Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Auckland Hospital , Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I M","family":"Holdaway","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Auckland , Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Foote","sequence":"additional","affiliation":[{"name":"Department of Radiology, Auckland Hospital , Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I R","family":"Reid","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Auckland , Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1990,12,1]]},"reference":[{"issue":"292","key":"ref_1","first-page":"1547","article-title":"Bone mineral content in Polynesian and white New Zealand women","volume":"1986","author":"Reid, I.R.; Mackie, M.; Ibbertson, H.K.","unstructured":"Reid, I.R., Mackie, M. & Ibbertson, H.K. Bone mineral content in Polynesian and white New Zealand women. Br Med J 1986, 292: 1547-1548.","journal-title":"Br Med J"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1148\/radiology.162.1.3786773","article-title":"Quantitative CT applications: Comparison of current scanners","volume":"162","author":"Cann, C.E.","year":"1987","unstructured":"Cann, C.E. Quantitative CT applications: Comparison of current scanners. Radiology 1987, 162: 257-261.","journal-title":"Radiology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1001\/archinte.1967.04410010063009","article-title":"Hypoparathyroidism. Clinical observations in 34 patients","volume":"120","author":"Dimich, A.; Bedrossian, P.B.; Wallach, S.","year":"1967","unstructured":"Dimich, A., Bedrossian, P.B. & Wallach, S. Hypoparathyroidism. Clinical observations in 34 patients. Arch Intern Med 1967, 120: 449-458.","journal-title":"Arch Intern Med"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0140-6736(70)92410-4","article-title":"Parathyroid activity and post-menopausal osteoporosis","volume":"i:","author":"Hossain, M.; Smith, D.A.; Nordin, B.E.C.","year":"1970","unstructured":"Hossain, M., Smith, D.A. & Nordin, B.E.C. Parathyroid activity and post-menopausal osteoporosis. Lancet 1970, i: 809-811.","journal-title":"Lancet"},{"key":"ref_5","first-page":"257","article-title":"Effect of postoperative hypoparathyroidism on bone density","volume":"34","author":"Hurxthal, L.M.; Dotter, W.E.; Vose, G.P.; Sprinkle, E.E.","year":"1976","unstructured":"Hurxthal, L.M., Dotter, W.E., Vose, G.P. & Sprinkle, E.E. Effect of postoperative hypoparathyroidism on bone density. Texas Rep Biol Med 1976, 34: 257-265.","journal-title":"Texas Rep Biol Med"},{"key":"ref_6","first-page":"329","article-title":"Metacarpal cortical dimensions in hypoparathyroidism, primary hyperparathyroidism and chronic renal failure","volume":"(Suppl):","author":"Parfitt, A.M.","year":"1977","unstructured":"Parfitt, A.M. Metacarpal cortical dimensions in hypoparathyroidism, primary hyperparathyroidism and chronic renal failure. Calcif Tissue Res 1977, 22 (Suppl): 329-331.","journal-title":"Calcif Tissue Res"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1172\/JCI110570","article-title":"Differential effects of endocrine dysfunction on the axial and the appendicular skeleton","volume":"69","author":"Seeman, E.; Wahner, H.W.; Offord, K.P.; Kumar, R.; Johnson, W.J.; Riggs, B.L.","year":"1982","unstructured":"Seeman, E., Wahner, H.W., Offord, K.P., Kumar, R., Johnson, W.J. & Riggs, B.L. Differential effects of endocrine dysfunction on the axial and the appendicular skeleton. J Clin Invest 1982, 69: 1302-1309.","journal-title":"J Clin Invest"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1172\/JCI114229","article-title":"The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion","volume":"84","author":"Brown, A.J.; Ritter, C.R.; Finch, J.L.","year":"1989","unstructured":"Brown, A.J., Ritter, C.R., Finch, J.L. et al. The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion. J Clin Invest 1989, 84: 728-732.","journal-title":"J Clin Invest"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/66\/782\/1061\/50077534\/postgradmedj-66-1061.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/66\/782\/1061\/50077534\/postgradmedj-66-1061.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T16:55:11Z","timestamp":1682614511000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/66\/782\/1061\/7061499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,12,1]]},"references-count":8,"journal-issue":{"issue":"782","published-online":{"date-parts":[[1990,12,1]]},"published-print":{"date-parts":[[1990,12,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.66.782.1061","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1990,12]]},"published":{"date-parts":[[1990,12,1]]}}}