{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:02:00Z","timestamp":1760266920833},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"785","license":[{"start":{"date-parts":[[1991,3,1]],"date-time":"1991-03-01T00:00:00Z","timestamp":667785600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Three cases of severe and irreversible alopecia occurring in patients with common variable immunodeficiency are described. In all three cases, hair loss developed after the diagnosis of immune deficiency; one of the patients also had extensive vitiligo. A fourth patient had vitiligo in the absence of alopecia. No change in the alopecia or vitiligo was noted in any patient as a result of immunoglobulin replacement therapy.<\/jats:p>","DOI":"10.1136\/pgmj.67.785.291","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"291-294","source":"Crossref","is-referenced-by-count":10,"title":["Alopecia totalis and vitiligo in common variable immunodeficiency"],"prefix":"10.1093","volume":"67","author":[{"given":"G","family":"Spickett","sequence":"first","affiliation":[{"name":"Department of Immunology, John Radeliffe Hospital , Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A G","family":"Prentice","sequence":"additional","affiliation":[{"name":"Derriford Hospital , Plymouth, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Wallington","sequence":"additional","affiliation":[{"name":"South Western Regional Transfusion Centre , Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A D B","family":"Webster","sequence":"additional","affiliation":[{"name":"Clinical Research Centre, Northwick Park Hospital , Harrow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Chapel","sequence":"additional","affiliation":[{"name":"Department of Immunology, John Radeliffe Hospital , Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1991,3,1]]},"reference":[{"key":"ref_1","article-title":"Diagnosis and Management of Immunodeficiency Disorders","author":"Asherson, G.L.; Webster, A.D.B.","year":"1980","unstructured":"Asherson, G.L. & Webster, A.D.B. Diagnosis and Management of Immunodeficiency Disorders. Blackwell Scientific Publications, Oxford, 1980."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/BF00917124","article-title":"Clinical and immunologic analyses of 103 patients with common variable immunodeficiency","volume":"9","author":"Cunningham-Rundles, C.","year":"1989","unstructured":"Cunningham-Rundles, C. Clinical and immunologic analyses of 103 patients with common variable immunodeficiency. J Clin Immunol 1989, 9: 22-33.","journal-title":"J Clin Immunol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S0022-3476(76)80791-3","article-title":"Antibody deficiency and alopecia","volume":"89","author":"Ipp, M.M.; Gelfand, E.W.","year":"1976","unstructured":"Ipp, M.M. & Gelfand, E.W. Antibody deficiency and alopecia. 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An apparent loss of contact hypersensitivity","volume":"1988","author":"Amornsiripanitch, S.; Barnes, L.M.; Nordlund, J.J.; Trinkle, L.S.; Rheins, L.A.","unstructured":"Amornsiripanitch, S., Barnes, L.M., Nordlund, J.J., Trinkle, L.S. & Rheins, L.A. Immune studies in the depigmenting C57BL\/Ler-vit\/vit mice. An apparent loss of contact hypersensitivity. J Immunol 1988, 140: 3438-3445.","journal-title":"J Immunol"},{"key":"ref_16","first-page":"269","article-title":"Immunopathological studies on alopecia areata","author":"Nunzi, E.; Hamerlinck, F.; Cormane, R.H.","year":"1980","unstructured":"Nunzi, E., Hamerlinck, F. & Cormane, R.H. Immunopathological studies on alopecia areata. Arch Dermatol Res 1980, 269 1-11.","journal-title":"Arch Dermatol Res"},{"key":"ref_17","first-page":"1335","article-title":"Alopecia areata - an autoimmune disease?","volume":"i:","author":"Editorial","year":"1984","unstructured":"Editorial. Alopecia areata - an autoimmune disease? Lancet 1984, i: 1335-1336.","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1111\/j.1365-2133.1987.tb07357.x","article-title":"Response to minoxidil in severe alopecia areata correlates with T lymphocyte stimulation","volume":"117","author":"Fiedler-Weiss, V.C.; Buys, C.M.","year":"1987","unstructured":"Fiedler-Weiss, V.C. & Buys, C.M. Response to minoxidil in severe alopecia areata correlates with T lymphocyte stimulation. Br J Dermatol 1987, 117: 759-763.","journal-title":"Br J Dermatol"},{"issue":"35","key":"ref_19","first-page":"143","article-title":"Diabetes mellitus in ataxia-telangiectasia, fanconi anemia, xeroderma pigmentosum, common variable immune deficiency and severe combined immune deficiency families","volume":"1986","author":"Morrell, D.; Chase, C.L.; Kupper, L.L.; Swift, M.","unstructured":"Morrell, D., Chase, C.L., Kupper, L.L. & Swift, M. Diabetes mellitus in ataxia-telangiectasia, fanconi anemia, xeroderma pigmentosum, common variable immune deficiency and severe combined immune deficiency families. Diabetes 1986, 35: 143-147.","journal-title":"Diabetes"},{"key":"ref_20","first-page":"199","article-title":"Cellular abnormalities in common variable immunodeficiency","volume":"2","author":"Spickett, G.P.; Webster, A.D.B.; Farrant, J.","year":"1990","unstructured":"Spickett, G.P., Webster, A.D.B. & Farrant, J. Cellular abnormalities in common variable immunodeficiency. Immunodef Rev 1990, 2: 199-219.","journal-title":"Immunodef Rev"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0190-9622(87)70252-7","article-title":"Human immunodeficiency virus-associated vitiligo: expression of autoimmunity with immunodeficiency?","volume":"17","author":"Duvic, M.; Rapini, R.; Hoots, W.K.; Mansell, P.W.","year":"1987","unstructured":"Duvic, M., Rapini, R., Hoots, W.K. & Mansell, P.W. 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