{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:31:10Z","timestamp":1761975070954},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"785","license":[{"start":{"date-parts":[[1991,3,1]],"date-time":"1991-03-01T00:00:00Z","timestamp":667785600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A nurse with common variable hypogammaglobulinaemia was found to excrete a non-vaccine strain type II poliovirus for almost a year following a bout of gastroenteritis. Attempts were made to halt intestinal carriage of the virus in view of the possible risk of spread to immunocompromised patients and the risk of paralytic poliomyelitis to the patient himself.<\/jats:p>\n               <jats:p>Three doses of killed Salk vaccine failed to stimulate salivary anti-polio antibodies. Excretion of the virus ceased spontaneously just before oral immunoglobulin containing high titres of antibodies to polio virus was used to halt virus excretion.<\/jats:p>","DOI":"10.1136\/pgmj.67.785.301","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"301-303","source":"Crossref","is-referenced-by-count":29,"title":["Prolonged faecal excretion of poliovirus in a nurse with common variable hypogammaglobulinaemia"],"prefix":"10.1093","volume":"67","author":[{"given":"S A","family":"Misbah","sequence":"first","affiliation":[{"name":"Department of Immunology, John Radcliffe Hospital , Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Lawrence","sequence":"additional","affiliation":[{"name":"Department of Occupational Health, Radcliffe Infirmary , Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J B","family":"Kurtz","sequence":"additional","affiliation":[{"name":"Department of Virology, John Radcliffe Hospital , Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H M","family":"Chapel","sequence":"additional","affiliation":[{"name":"Department of Immunology, John Radcliffe Hospital , Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1991,3,1]]},"reference":[{"key":"ref_1","first-page":"25","article-title":"Hypogammaglobulinaemia in the United Kingdom. Medical Research Council special report series 310. Her Majesty's Stationery Office","author":"party on Hypogammaglobulinaemia, Working","year":"1971","unstructured":"Working party on Hypogammaglobulinaemia. Hypogammaglobulinaemia in the United Kingdom. Medical Research Council special report series 310. Her Majesty's Stationery Office. London. 1971, pp. 25, 80."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1093\/clinids\/9.2.334","article-title":"Chronic enteroviral meningoencephalitis in agammaglobulinaemic patients","volume":"9","author":"McKinney, R.E.; Katz, S.L.; Wilfert, C.M.","year":"1987","unstructured":"McKinney, R.E., Katz, S.L. & Wilfert, C.M. Chronic enteroviral meningoencephalitis in agammaglobulinaemic patients. Rev Infect Dis 1987, 9: 334-356.","journal-title":"Rev Infect Dis"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1093\/infdis\/146.5.712","article-title":"Prolonged excretion ofGroup A Coxsackie virus in an infant with agammaglobulinaemia","volume":"146","author":"Johnson, J.P.; Yolken, R.H.; Goodman, D.; Winkelstein, J.A.; Nagel, J.E.","year":"1982","unstructured":"Johnson, J.P., Yolken, R.H., Goodman, D., Winkelstein, J.A. & Nagel, J.E. Prolonged excretion ofGroup A Coxsackie virus in an infant with agammaglobulinaemia. J Infect Dis 1982, 146: 712.","journal-title":"J Infect Dis"},{"key":"ref_4","first-page":"318","article-title":"Coxsackie A15 enteritis and encephalitis in agammaglobulinaemia","volume":"20","author":"O'Neil, K.M.; Modlin, J.F.; Lock, T.M.; Winkelstein, J.A.","year":"1986","unstructured":"O'Neil, K.M., Modlin, J.F., Lock, T.M. & Winkelstein, J.A. Coxsackie A15 enteritis and encephalitis in agammaglobulinaemia. Pediatric Res 1986, 20: 318A.","journal-title":"Pediatric Res"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1093\/infdis\/143.5.707","article-title":"Antibody responses to live and killed poliovirus vaccines in the milk of Pakistani and Swedish women","volume":"143","author":"Svennerholm, A.M.; Hanson, L.A.; Holmgren, J.","year":"1981","unstructured":"Svennerholm, A.M., Hanson, L.A., Holmgren, J. et al. Antibody responses to live and killed poliovirus vaccines in the milk of Pakistani and Swedish women. J Infect Dis 1981, 143: 707-711.","journal-title":"J Infect Dis"},{"issue":"37","key":"ref_6","first-page":"630","article-title":"Paralytic poliomyelitis in a child with hypogammaglobulinaemia","volume":"1966","author":"Chang, T.W.; Weinstein, L.; McMahon, H.E.","unstructured":"Chang, T.W., Weinstein, L. & McMahon, H.E. Paralytic poliomyelitis in a child with hypogammaglobulinaemia. Pediatrics 1966, 37: 630-636.","journal-title":"Pediatrics"},{"issue":"8","key":"ref_7","first-page":"89","article-title":"Inadequacy of mucosal IgM antibodies in selective IgA deficiency: Excretion of attenuated poliovirus is prolonged","volume":"1988","author":"Savilahti, E.; Klemola, T.; Carlsson, B.; Mellander, L.; Stenvik, M.; Hovi, T.","unstructured":"Savilahti, E., Klemola, T., Carlsson, B., Mellander, L., Stenvik, M. & Hovi, T. Inadequacy of mucosal IgM antibodies in selective IgA deficiency: Excretion of attenuated poliovirus is prolonged. J Clin Immunol 1988, 8: 89-94.","journal-title":"J Clin Immunol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1111\/j.1348-0421.1981.tb00095.x","article-title":"Antigenic analysis of polioviruses isolated from a child with agammaglobulinaemia and paralytic poliomyelitis after Sabin vaccine administration","volume":"25","author":"Hara, M.; Saito, Y.; Komatsu, T.","year":"1981","unstructured":"Hara, M., Saito, Y., Komatsu, T. et al. Antigenic analysis of polioviruses isolated from a child with agammaglobulinaemia and paralytic poliomyelitis after Sabin vaccine administration. Microbiol Immunol 1981, 25: 905-913.","journal-title":"Microbiol Immunol"},{"issue":"314","key":"ref_9","first-page":"548","article-title":"Increased neurovirulence associated with a single nucleotide change in a noncoding region of the Sabin type 3 poliovaccine genome","volume":"1985","author":"Evans, D.M.A.; Dunn, G.; Minor, P.D.","unstructured":"Evans, D.M.A., Dunn, G., Minor, P.D. et al. Increased neurovirulence associated with a single nucleotide change in a noncoding region of the Sabin type 3 poliovaccine genome. Nature 1985, 314: 548-550.","journal-title":"Nature"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/67\/785\/301\/50075381\/postgradmedj-67-301.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/67\/785\/301\/50075381\/postgradmedj-67-301.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T16:19:26Z","timestamp":1682612366000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/67\/785\/301\/7061615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3,1]]},"references-count":9,"journal-issue":{"issue":"785","published-online":{"date-parts":[[1991,3,1]]},"published-print":{"date-parts":[[1991,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.67.785.301","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1991,3]]},"published":{"date-parts":[[1991,3,1]]}}}