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J Hepatol 1989, 9: S130 (abstr).","journal-title":"J Hepatol"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0168-8278(90)91385-A","article-title":"M2 antibodies and Rough (R) mutants in urine of 'normal' women with recurrent bacteriuria, and in women with PBC","volume":"11","author":"Burroughs, A.K.; Butler, P.; Valle, F.","year":"1990","unstructured":"Burroughs, A.K., Butler, P., Valle, F. et al. M2 antibodies and Rough (R) mutants in urine of 'normal' women with recurrent bacteriuria, and in women with PBC. J Hepatol 1990, 11: S13 (abstr).","journal-title":"J Hepatol"},{"key":"ref_49","first-page":"1419","article-title":"Relation between Escherichia coli R (rough) - forms in gut, lipid A in liver, and primary biliary cirrhosis","volume":"ii:","author":"Hopf, U.; Stemerowicz, R.; Rodloff, A.","year":"1989","unstructured":"Hopf, U., Stemerowicz, R., Rodloff, A. et al. Relation between Escherichia coli R (rough) - forms in gut, lipid A in liver, and primary biliary cirrhosis. Lancet 1989, ii: 1419-1421.","journal-title":"Lancet"},{"key":"ref_50","first-page":"125","article-title":"Bacteriuria and primary biliary cirrhosis","volume-title":"Microbial Diseases in Nephrology","author":"Rosenstein, I.J.M.; Burroughs, A.K.","year":"1986","unstructured":"Rosenstein, IJ.M. & Burroughs, A.K. Bacteriuria and primary biliary cirrhosis. In: Asscher, A.W. & Brumfitt, W. (eds) Microbial Diseases in Nephrology. John Wiley & Sons, Bath, 1986, pp. 125-135."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/gut.16.11.871","article-title":"Antibodies to Escherichia coli in chronic liver disease","volume":"16","author":"Simjee, A.; Hamilton-Miller, J.M.T.; Thomas, H.C.","year":"1975","unstructured":"Simjee, A., Hamilton-Miller, J.M.T., Thomas, H.C. et al. Antibodies to Escherichia coli in chronic liver disease. Gut 1975, 16: 871-875.","journal-title":"Gut"},{"key":"ref_52","first-page":"1009","article-title":"Aberrant expression of HLA-DR antigens on bile duct epithelium in primary biliary cirrhosis: relevance to pathogenesis","volume":"Ui,","author":"Ballardini, G.; Bianchi, F.B.; Doniach, D.; Mirakian, R.; Pisi, E.; Bottazzo, G.F.","year":"1984","unstructured":"Ballardini, G., Bianchi, F.B., Doniach, D., Mirakian, R., Pisi, E. & Bottazzo, G.F. Aberrant expression of HLA-DR antigens on bile duct epithelium in primary biliary cirrhosis: relevance to pathogenesis. Lancet 1984, Ui, 1009-1013.","journal-title":"Lancet"},{"issue":"9","key":"ref_53","first-page":"132","article-title":"New immunopathologic features in primary biliary cirrhosis","volume":"1986","author":"Pisi, E.; Bianchi, F.B.; Ballardini, G.; Cassani, F.; Bottazzo, G.F.","unstructured":"Pisi, E., Bianchi, F.B., Ballardini, G., Cassani, F. & Bottazzo, G.F. New immunopathologic features in primary biliary cirrhosis. Front Gastrointest Res 1986, 9: 132-142.","journal-title":"Front Gastrointest Res"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1002\/hep.1840070516","article-title":"Primary biliary cirrhosis: associations with II major histocompatibility complex antigen","volume":"7","author":"Gores, G.J.; Moore, S.B.; Fisher, L.D.; Powell, F.C.; Dickson, F.R.","year":"1987","unstructured":"Gores, G.J., Moore, S.B., Fisher, L.D., Powell, F.C. & Dickson, F.R. Primary biliary cirrhosis: associations with II major histocompatibility complex antigen. Hepatology 1987, 7: 889-892.","journal-title":"Hepatology"},{"issue":"8","key":"ref_55","first-page":"449","article-title":"Expression of class I and class II major histocompatibility complex antigens on human hepatocytes","volume":"1988","author":"Franco, A.; Barnaba, V.; Natali, P.; Balsano, C.; Musca, A.; Balsano, F.","unstructured":"Franco, A., Barnaba, V., Natali, P., Balsano, C., Musca, A. & Balsano, F. Expression of class I and class II major histocompatibility complex antigens on human hepatocytes. Hepatology 1988, 8: 449-454.","journal-title":"Hepatology"},{"key":"ref_56","first-page":"336","article-title":"Induction of intracellular adhesion molecule - I (ICAM-I) on HEPG 2 cells: influence of cytokines and HBV-DNA transfection","volume":"12","author":"Volpes, R.; Sing-Hiem, Y.; Joost, J.; Van de Oord, J.; Acsq, G.; Desmet, V.J.","year":"1990","unstructured":"Volpes, R., Sing-Hiem, Y., Joost, J., Van de Oord, J., Acsq, G. & Desmet, V.J. Induction of intracellular adhesion molecule - I (ICAM-I) on HEPG 2 cells: influence of cytokines and HBV-DNA transfection. Hepatology 1990, 12: 336 (Abstr).","journal-title":"Hepatology"},{"issue":"62","key":"ref_57","first-page":"545","article-title":"An immunohistological study of human hepatic graft-versus-host disease","volume":"1985","author":"Dilly, D.; Sloane, J.P.","unstructured":"Dilly, D. & Sloane, J.P. An immunohistological study of human hepatic graft-versus-host disease. Clin Exp Immunol 1985, 62: 545-553.","journal-title":"Clin Exp Immunol"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0168-8278(87)80571-8","article-title":"Expression of MHC class II antigens on bile duct epithelia in patients with hepatic graft-versus-host disease after bone marrow transplantation","volume":"5","author":"Miglio, F.; Pignatelli, M.; Mazzeo, V.","year":"1987","unstructured":"Miglio, F., Pignatelli, M., Mazzeo, V. et al. Expression of MHC class II antigens on bile duct epithelia in patients with hepatic graft-versus-host disease after bone marrow transplantation. J Hepatol 1987, 5: 182-189.","journal-title":"J Hepatol"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1136\/jcp.40.8.879","article-title":"Immunocytochemical analysis of HLA class II (DR) antigens in liver disease in man","volume":"40","author":"Barbatis, C.; Kelly, P.; Greveson, J.; Heryet, A.; McGee, O.'D.; J.","year":"1987","unstructured":"Barbatis, C., Kelly, P., Greveson, J., Heryet, A. & O'D McGee, J. Immunocytochemical analysis of HLA class II (DR) antigens in liver disease in man. J Clin Pathol 1987, 40: 879-884.","journal-title":"J Clin Pathol"},{"issue":"8","key":"ref_60","first-page":"459","article-title":"Differential expression of MHC class II subregion products on bile duct epithelial cells and hepatocytes in patients with primary biliary cirrhosis","volume":"1988","author":"Spengler, U.; Pape, G.R.; Hoffmann, R.M.","unstructured":"Spengler, U., Pape, G.R., Hoffmann, R.M. et al. Differential expression of MHC class II subregion products on bile duct epithelial cells and hepatocytes in patients with primary biliary cirrhosis. Hepatology 1988, 8: 459-462.","journal-title":"Hepatology"},{"issue":"29","key":"ref_61","first-page":"422","article-title":"Expression of HLA-DR antigens on bile duct epithelia in primary sclerosing cholangitis","volume":"1988","author":"Chapman, R.W.; Kelly, P.; Heryat, A.","unstructured":"Chapman, R.W., Kelly, P., Heryat, A. et al. Expression of HLA-DR antigens on bile duct epithelia in primary sclerosing cholangitis. Gut 1988, 29: 422-427.","journal-title":"Gut"},{"key":"ref_62","first-page":"95","article-title":"Preferential activation of helper\/ inducer T lymphocytes in autoimmune chronic active hepatitis. Clin Exp Immunol","volume":"67","author":"Lobo-Yeo, A.; Alviggi, L.; Mieli-Vargani, G.; Portmann, B.; Mowat, A.P.; Vergani, D.","year":"1987","unstructured":"Lobo-Yeo, A., Alviggi, L., Mieli-Vargani, G., Portmann, B., Mowat, A.P. & Vergani, D. Preferential activation of helper\/ inducer T lymphocytes in autoimmune chronic active hepatitis. Clin Exp Immunol 1987, 67: 95-104."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/hep.1840120219","article-title":"Analysis of hepatic T lymphocyte and immunoglobulin deposits in patients with primary biliary cirrhosis","volume":"12","author":"Krams, S.M.; Van de Water, J.; Coppel, R.L.","year":"1990","unstructured":"Krams, S.M., Van de Water, J., Coppel, R.L. et al. Analysis of hepatic T lymphocyte and immunoglobulin deposits in patients with primary biliary cirrhosis. Hepatology 1990, 12: 306-313.","journal-title":"Hepatology"},{"issue":"6","key":"ref_64","first-page":"385","article-title":"Ultrastructural immunocytochemical analysis of lymphocytes infiltrating bile duct epithelia in primary biliary cirrhosis","volume":"1986","author":"Yamada, G.; Hyodo, I.; Tobe, K.","unstructured":"Yamada, G., Hyodo, I., Tobe, K. et al. Ultrastructural immunocytochemical analysis of lymphocytes infiltrating bile duct epithelia in primary biliary cirrhosis. Hepatology 1986, 6: 385-391.","journal-title":"Hepatology"},{"issue":"87","key":"ref_65","first-page":"763","article-title":"T-lymphocyte sensitization to hepatocyte antigens in autoimmune chronic active hepatitis and primary biliary cirrhosis","volume":"1984","author":"Vento, S.; O'Brien, C.J.; McFarlane, B.M.; McFarlane, I.G.; Eddlestone, A.; Williams, R.","unstructured":"Vento, S., O'Brien, C.J., McFarlane, B.M., McFarlane, I.G., Eddlestone, A. & Williams, R. T-lymphocyte sensitization to hepatocyte antigens in autoimmune chronic active hepatitis and primary biliary cirrhosis. Gastroenterology 1984, 87: 763-769.","journal-title":"Gastroenterology"},{"key":"ref_66","first-page":"95","article-title":"Clonal analysis of liver-derived T cells of patients with PBC. Clin Exp Immunol","volume":"67","author":"Hoffmann, R.M.; Paper, G.R.; Spengler, U.","year":"1987","unstructured":"Hoffmann, R.M., Paper, G.R., Spengler, U. et al. Clonal analysis of liver-derived T cells of patients with PBC. Clin Exp Immunol 1987, 67: 95-104."},{"issue":"18","key":"ref_67","first-page":"1447","article-title":"Clonal analysis of human T lymphocyte infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis","volume":"1988","author":"Meuer, S.C.; Moebius, U.; Manns, M.","unstructured":"Meuer, S.C., Moebius, U., Manns, M. et al. Clonal analysis of human T lymphocyte infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis. Eur JImmunol 1988, 18: 1447-1452.","journal-title":"Eur JImmunol"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/hep.1840070421","article-title":"Evidence for the cell-surface localization of antigens cross-reacting with the 'mitochondrial antibodies' ofprimary biliary cirrhosis","volume":"7","author":"Ghadiminejed, I.; Baum, H.","year":"1987","unstructured":"Ghadiminejed, I. & Baum, H. Evidence for the cell-surface localization of antigens cross-reacting with the 'mitochondrial antibodies' ofprimary biliary cirrhosis. Hepatology 1987, 7: 743-750.","journal-title":"Hepatology"},{"issue":"8","key":"ref_69","first-page":"706","volume":"1988","author":"Ghadiminejed, I.; Baum, H.","unstructured":"Ghadiminejed, I. & Baum, H. Hepatology 1988, 8: 706-707 (correspondence).","journal-title":"Hepatology"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/329512a0","article-title":"The foreign antigen binding site and T cell recognition regions ofclass I histocompatibility antigens","volume":"329","author":"Bjorkman, P.J.; Saper, M.A.; Samraoudi, B.; Bennett, W.S.; Strominger, J.L.; Wiley, C.D.","year":"1987","unstructured":"Bjorkman, P.J., Saper, M.A., Samraoudi, B., Bennett, W.S., Strominger, J.L. & Wiley, C.D. The foreign antigen binding site and T cell recognition regions ofclass I histocompatibility antigens. Nature 1987, 329: 512-518.","journal-title":"Nature"},{"issue":"287","key":"ref_71","article-title":"Presence of cytochrome P-450 on human hepatocyte plasma membrane. Recognition of several autoantibodies","volume":"12","author":"Loeper, J.; Descatoire, V.; Maurice, M.","year":"1990","unstructured":"Loeper, J., Descatoire, V., Maurice, M. et al. Presence of cytochrome P-450 on human hepatocyte plasma membrane. Recognition of several autoantibodies. Hepatology 1990, 12: 287 (abstr).","journal-title":"Hepatology"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0950-3579(89)80024-X","article-title":"The relationship between Klebsiella infection and ankylosing spondylitis","volume":"3","author":"Ebringer, A.","year":"1989","unstructured":"Ebringer, A. The relationship between Klebsiella infection and ankylosing spondylitis. Bailliere's Clinical Rheumatology 1989, 3: 321-338.","journal-title":"Bailliere's Clinical Rheumatology"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0140-6736(90)90804-E","article-title":"Salmonella lipopolysaccharide in synovial cells from patients with reactive arthritis","volume":"335","author":"Granfers, K.; Jalkanen, S.; Lindberg, A.A.","year":"1990","unstructured":"Granfers, K., Jalkanen, S., Lindberg, A.A. et al. Salmonella lipopolysaccharide in synovial cells from patients with reactive arthritis. Lancet 1990, 335: 685-688.","journal-title":"Lancet"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1136\/ard.50.2.87","article-title":"Bacterial antigens in synovial biopsy specimens in Yersinia triggered reactive arthritis","volume":"50","author":"Marilahti-Palo, R.; Soderstron, K.-O.; Lahesmaa-Rantala, R.; Granfors, K.; Toiranan, A.","year":"1991","unstructured":"Marilahti-Palo, R., Soderstron, K.-O., Lahesmaa-Rantala, R., Granfors, K. & Toiranan, A. Bacterial antigens in synovial biopsy specimens in Yersinia triggered reactive arthritis. Ann Rheum Dis 1991, 50: 87-90.","journal-title":"Ann Rheum Dis"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF00271885","article-title":"Rheumatoid arthritis and Proteus: a possible aetiological association","volume":"9","author":"Ebringer, A.; Khalafpour, S.; Wilson, C.","year":"1989","unstructured":"Ebringer, A., Khalafpour, S. & Wilson, C. Rheumatoid arthritis and Proteus: a possible aetiological association. Rheumatol Int 1989, 9: 223-228.","journal-title":"Rheumatol Int"},{"key":"ref_76","first-page":"312","article-title":"Sharing of antigenic determinants between the nicotinic acetylcholine receptor and proteins in E. colt, Proteus vulgaris and Klebsiella pneumoniae","volume":"1985","author":"Stefansson, K.; Dieperink, M.E.; Richman, D.P.; Gomez, C.M.; Marton, L.S.","unstructured":"Stefansson, K., Dieperink, M.E., Richman, D.P., Gomez, C.M. & Marton, L.S. Sharing of antigenic determinants between the nicotinic acetylcholine receptor and proteins in E. colt, Proteus vulgaris and Klebsiella pneumoniae. N Engl J Med 1985, 312: 221-225.","journal-title":"N Engl J Med"},{"issue":"6","key":"ref_77","first-page":"283","article-title":"Immunochemical characterization of anti-acetylcholine receptor antibodies in primary biliary cirrhosis","volume":"1988","author":"Kyriatsoulis, A.; Manns, M.; Gerken, G.","unstructured":"Kyriatsoulis, A., Manns, M., Gerken, G. et al. Immunochemical characterization of anti-acetylcholine receptor antibodies in primary biliary cirrhosis. J Hepatol 1988, 6: 283-290.","journal-title":"J Hepatol"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1600-0404.1989.tb03871.x","article-title":"Characterization of acetylcholine receptor antibodies in a patient with primary biliary cirrhosis","volume":"80","author":"Lefvert, A.K.; Holm, G.","year":"1989","unstructured":"Lefvert, A.K. & Holm, G. Characterization of acetylcholine receptor antibodies in a patient with primary biliary cirrhosis. 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