{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:16:24Z","timestamp":1758478584265},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"794","license":[{"start":{"date-parts":[[1991,12,1]],"date-time":"1991-12-01T00:00:00Z","timestamp":691545600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,12,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 16 year old girl with Type 1 Gaucher's disease presented with massive splenomegaly, hypersplenism and abdominal discomfort. Traditionally hypersplenism has been treated with splenectomy, but this results in a high incidence of overwhelming sepsis and accelerated sphingolipid deposition in both liver and bone. A 90% partial splenectomy was therefore performed leaving a fully vascularized inferior segment of the spleen and resecting 5.8 kg of splenic tissue. The patient made an uneventful recovery with a marked improvement in her haematological parameters and general condition.<\/jats:p>","DOI":"10.1136\/pgmj.67.794.1072","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"1072-1074","source":"Crossref","is-referenced-by-count":3,"title":["Partial splenectomy for massive splenomegaly secondary to Gaucher's disease"],"prefix":"10.1093","volume":"67","author":[{"given":"W E G","family":"Thomas","sequence":"first","affiliation":[{"name":"Departments of Surgery and Haematology, Royal Hallamshire Hospital , Glossop Road, Sheffield S10 2JF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Winfield","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Haematology, Royal Hallamshire Hospital , Glossop Road, Sheffield S10 2JF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1991,12,1]]},"reference":[{"issue":"221 -225","key":"ref_1","article-title":"Metabolism of glucocerebrosides. 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Prog Pediatr Surg 1985, 18: 162-168.","journal-title":"Prog Pediatr Surg"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0022-3468(78)80097-9","article-title":"Partial splenectomy in staging laparotomy for Hodgkin's disease: an alternative approach","volume":"13","author":"Boles, E.T.; Haase, G.M.; Hamoudi, A.B.","year":"1979","unstructured":"Boles, E.T., Haase, G.M. & Hamoudi, A.B. Partial splenectomy in staging laparotomy for Hodgkin's disease: an alternative approach. J Paediat Surg 1979, 13: 581-586.","journal-title":"J Paediat Surg"},{"issue":"76","key":"ref_14","first-page":"398","article-title":"Partial splenectomy in children with Gaucher's disease","volume":"1985","author":"Bar-Maor, J.A.; Govrin-Yedudain, J.","unstructured":"Bar-Maor, J.A. & Govrin-Yedudain, J. Partial splenectomy in children with Gaucher's disease. Pediatrics 1985, 76: 398-401.","journal-title":"Pediatrics"},{"key":"ref_15","first-page":"125","volume":"21","author":"Rubin, M.; Yampolski, I.; Lambrozo, E.","year":"1986","unstructured":"Rubin, M., Yampolski, I., Lambrozo, E. et al. Partial splenectomy in Gaucher's disease. J Paediat Surg 1986, 21: 125-128.","journal-title":"et al. Partial splenectomy in Gaucher's disease. J Paediat Surg"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1097\/00000658-198706000-00011","article-title":"Partial splenectomy for Gaucher's disease","volume":"205","author":"Rodgers, B.M.; Tribble, C.; Joob, A.","year":"1987","unstructured":"Rodgers, B.M., Tribble, C. & Joob, A. Partial splenectomy for Gaucher's disease. 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