{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T23:24:12Z","timestamp":1692660252505},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"801","license":[{"start":{"date-parts":[[1992,7,1]],"date-time":"1992-07-01T00:00:00Z","timestamp":709948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1992,7,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 35 year old woman presented with severe primary hypothyroidism and galactorrhea. A very high prolactin level was also detected and computerized tomography scan of the sellar region demonstrated an enlarged pituitary gland associated with contrast enhancement. Replacement therapy with thyroxine corrected both biochemical and clinical abnormalities but empty sella developed during this therapy. It is concluded that empty sella may be related to thyroxine-induced shrinkage of lactotroph and\/or thyrotroph cell hyperplasia.<\/jats:p>","DOI":"10.1136\/pgmj.68.801.589","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"589-591","source":"Crossref","is-referenced-by-count":7,"title":["Empty sella developing during thyroxine therapy in a patient with primary hypothyroidism and hyperprolactinaemia"],"prefix":"10.1093","volume":"68","author":[{"given":"Fahrettin","family":"Kelestimur","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Ericyes University Medical School , Kayseri, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Sel\u00e7uklu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ericyes University Medical School , Kayseri, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevzat","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ericyes University Medical School , Kayseri, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1992,7,1]]},"reference":[{"key":"ref_1","first-page":"35","article-title":"Hypothalamicpituitary region: computed tomography imaging","volume":"3","author":"Bonneville, J.F.; Cattin, F.; Dieteman, J.L.","year":"1989","unstructured":"Bonneville, J.F., Cattin, F. & Dieteman, J.L. Hypothalamicpituitary region: computed tomography imaging. Endocrinol Metab Clin North Am 1989, 3: 35-72.","journal-title":"Endocrinol Metab Clin North Am"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1001\/archinte.1975.00330110109016","article-title":"Empty sella syndrome: sequela of the spontaneous remission ofacromegaly","volume":"135","author":"Login, I.; Santen, R.J.","year":"1975","unstructured":"Login, I. & Santen, R.J. Empty sella syndrome: sequela of the spontaneous remission ofacromegaly. Arch Intern Med 1975, 135: 1519-1521.","journal-title":"Arch Intern Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/0002-9343(83)90437-0","article-title":"Empty sella of normal size in Sheehan's syndrome","volume":"75","author":"Fleckman, A.M.; Schubart, U.K.; Danziger, A.; Fleischer, N.","year":"1983","unstructured":"Fleckman, A.M., Schubart, U.K., Danziger, A. & Fleischer, N. 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Hypothyroidism presenting with hyperprolactinaemia. 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