{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:42:52Z","timestamp":1792147372762,"version":"4.4.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"806","license":[{"start":{"date-parts":[[1992,12,1]],"date-time":"1992-12-01T00:00:00Z","timestamp":723168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1992,12,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Major biliary tract obstruction caused by tumour invasion is a rare manifestation of hepatocellular carcinoma. The authors had the opportunity to diagnose and treat five such cases, three of whom had features of acute cholangitis. The prevalence of both hepatocellular carcinoma and recurrent pyogenic cholangitis is high in patients from the Far East. The former may first present under the guise of the latter. Gastroenterologists and surgeons should be aware of hepatocellular carcinoma when managing these patients who present with obstructive jaundice, gross hepatomegaly and cholangitis.<\/jats:p>","DOI":"10.1136\/pgmj.68.806.961","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:01:03Z","timestamp":1230584463000},"page":"961-963","source":"Crossref","is-referenced-by-count":14,"title":["Biliary tract invasion and obstruction by hepatocellular carcinoma: report of five cases"],"prefix":"10.1093","volume":"68","author":[{"given":"S T","family":"Lai","sequence":"first","affiliation":[{"name":"Medical B, Princess Margaret Hospital , Kowloon, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K T","family":"Lam","sequence":"additional","affiliation":[{"name":"Surgical B, Princess Margaret Hospital , Kowloon, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K C","family":"Lee","sequence":"additional","affiliation":[{"name":"Clinical Pathology Units, Princess Margaret Hospital , Kowloon, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1992,12,1]]},"reference":[{"key":"ref_1","first-page":"47","article-title":"Clinical features of hepatocellular carcinoma: review of 211 patients in Hong Kong","volume":"1981","author":"Lai, C.L.; Lam, K.C.; Wong, K.P.; Wu, P.C.; Todd, D.","unstructured":"Lai, C.L., Lam, K.C., Wong, K.P., Wu, P.C. & Todd, D. Clinical features of hepatocellular carcinoma: review of 211 patients in Hong Kong. Cancer 1981, 47: 2746-2755.","journal-title":"Cancer"},{"key":"ref_2","first-page":"83","article-title":"Clinical manifestations of hepatoma. A review of 6 years' experience at a cancer hospital","volume":"56","author":"Ihde, D.C.; Sherlock, P.; Winawer, S.J.; Fortner, J.G.","year":"1974","unstructured":"Ihde, D.C., Sherlock, P., Winawer, S.J. & Fortner, J.G. Clinical manifestations of hepatoma. A review of 6 years' experience at a cancer hospital. Am J Med 1974, 56: 83-91.","journal-title":"Am J Med"},{"key":"ref_3","first-page":"387","article-title":"Clinical aspects of hepatocellular carcinoma analysis of 134 cases","author":"Okuda, K.","year":"1976","unstructured":"Okuda, K. Clinical aspects of hepatocellular carcinoma analysis of 134 cases. In: Okuda, K. & Peters, R.L. (ed.) Hepatocellular Carcinoma. 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