{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T14:38:17Z","timestamp":1719067097312},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"808","license":[{"start":{"date-parts":[[1993,2,1]],"date-time":"1993-02-01T00:00:00Z","timestamp":728524800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Gastric acid secretion was studied in 20 patients with typhoid fever (Group A), ten patients with fever other than typhoid (Group B), and ten healthy adults of matched age and sex (Group C). Patients with typhoid showed reduced acid secretion at the time of fever and one week after subsidence of fever as compared to Group C. In uncomplicated patients (Group A1), these values rose thereafter but in complicated patients (Group A2) they remained low even 12 weeks after subsidence of fever. This suggests that these patients had pre-existing hypochlorhydria which predisposed them to a severe form of disease. There may be many factors playing a significant role in making typhoid patients more prone to develop complications but the importance of gastric acid levels has also to be considered.<\/jats:p>","DOI":"10.1136\/pgmj.69.808.121","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"121-123","source":"Crossref","is-referenced-by-count":9,"title":["Gastric acid secretion in typhoid fever"],"prefix":"10.1093","volume":"69","author":[{"given":"S N","family":"Khosla","sequence":"first","affiliation":[{"name":"Department of Medicine, Medical College & Hospital , Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navleen","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Medicine, Medical College & Hospital , Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Khosla","sequence":"additional","affiliation":[{"name":"Department of Medicine, Medical College & Hospital , Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,2,1]]},"reference":[{"issue":"78","key":"ref_1","first-page":"281","article-title":"Influence of gastric acidity on bacterial and parasitic enteric infection. A perspective","volume":"1973","author":"Gianella, R.A.; Broitman, S.A.; Zamechek, N.","unstructured":"Gianella, R.A., Broitman, S.A. & Zamechek, N. Influence of gastric acidity on bacterial and parasitic enteric infection. A perspective. Ann Intern Med 1973, 78: 281-286.","journal-title":"Ann Intern Med"},{"key":"ref_2","article-title":"Salmonella enteritis","author":"Giannella, R.A.; Broitman, S.; Zamechek, N.","unstructured":"Giannella, R.A., Broitman, S. & Zamechek, N. Salmonella enteritis."},{"key":"ref_3","first-page":"1000","article-title":"Role ofreduced gastric secretions in pathogenesis","volume":"16","year":"1971","unstructured":"Role ofreduced gastric secretions in pathogenesis. Am JDigDis 1971, 16: 1000-1006.","journal-title":"Am JDigDis"},{"issue":"255","key":"ref_4","first-page":"555","article-title":"Association of Salmonella enteritis with operation on the stomach","volume":"1956","author":"Waddel, W.R.; Kunj, L.J.","unstructured":"Waddel, W.R. & Kunj, L.J. Association of Salmonella enteritis with operation on the stomach. N Engl J Med 1956, 255: 555-559.","journal-title":"N Engl J Med"},{"issue":"26","key":"ref_5","first-page":"491","article-title":"Gastric acid secretion in patients with typhoid fever","volume":"1985","author":"Bhalla, S.; ViJ, J.C.; Anand, B.S.","unstructured":"Bhalla, S., ViJ, J.C. & Anand, B.S. Gastric acid secretion in patients with typhoid fever. Gut 1985, 26: 491-494.","journal-title":"Gut"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1136\/bmj.1.5694.458","article-title":"Position of subject and of nasogastric tube during gastric secretion study","volume":"1","author":"Hassan, M.A.; Hobsley, M.","year":"1970","unstructured":"Hassan, M.A. & Hobsley, M. Position of subject and of nasogastric tube during gastric secretion study. Br Med J 1970, 1: 458-460.","journal-title":"Br Med J"},{"key":"ref_7","first-page":"422","article-title":"Transitory character of achlorhydria during fever demonstrated by","volume-title":"histamine test. Proc Soc Exp Biol Med 1929","volume":"26","author":"Bergluard, H.; Chang, H.C.","unstructured":"Bergluard, H. & Chang, H.C. Transitory character of achlorhydria during fever demonstrated by histamine test. Proc Soc Exp Biol Med 1929, 26: 422-423."},{"issue":"12","key":"ref_8","first-page":"155","article-title":"Gastric secretion in fever and infectious disease","volume":"1933","author":"Chang, H.C.","unstructured":"Chang, H.C. Gastric secretion in fever and infectious disease. J Clin Invest 1933, 12: 155-169.","journal-title":"J Clin Invest"},{"key":"ref_9","first-page":"31","article-title":"Gastric acidity in cholera and non-cholera diarrhoea","author":"Sack, G.H.; Pierce, N.; Mitra, R.C.; Sack, R.B.","year":"1972","unstructured":"Sack, G.H., Pierce, N., Mitra, R.C. & Sack, R.B. Gastric acidity in cholera and non-cholera diarrhoea. 1972,47:31-36."},{"issue":"188","key":"ref_10","first-page":"1","article-title":"Intrinsic factor in tapeworm anaemia","volume":"1970","author":"Salokannel, J.","unstructured":"Salokannel, J. Intrinsic factor in tapeworm anaemia. Acta Med Scand (Suppl) 1970, 188, 1-51.","journal-title":"Acta Med Scand (Suppl)"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0016-5085(19)34234-9","article-title":"Clinical giardiasis and intestinal malabsorption","volume":"53","author":"Hoskins, I.C.; Winawer, S.J.; Broitman, S.A.","year":"1967","unstructured":"Hoskins, I.C., Winawer, S.J. & Broitman, S.A. Clinical giardiasis and intestinal malabsorption. Gastroenterology 1967, 53: 265-270.","journal-title":"Gastroenterology"},{"key":"ref_12","first-page":"743","volume-title":"Clinical studies in human strongyloidiasis. Gastroenterology 1950","volume":"16","author":"Jones, C.A.","unstructured":"Jones, C.A. Clinical studies in human strongyloidiasis. Gastroenterology 1950, 16: 743-756."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/69\/808\/121\/50072682\/postgradmedj-69-121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/69\/808\/121\/50072682\/postgradmedj-69-121.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T18:52:19Z","timestamp":1682535139000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/69\/808\/121\/7062825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,2,1]]},"references-count":12,"journal-issue":{"issue":"808","published-online":{"date-parts":[[1993,2,1]]},"published-print":{"date-parts":[[1993,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.69.808.121","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1993,2]]},"published":{"date-parts":[[1993,2,1]]}}}