{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:47:34Z","timestamp":1791960454448,"version":"4.3.4"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"808","license":[{"start":{"date-parts":[[1993,2,1]],"date-time":"1993-02-01T00:00:00Z","timestamp":728524800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 5 year old girl with tuberculous meningitis developed progressive visual failure during in-patient anti-tuberculous chemotherapy due to an ophthochiasmatic tuberculoma. This was successfully managed by prolonged high-dose corticosteroids and continued anti-tuberculous therapy resulting in complete visual and psychosocial recovery.<\/jats:p>","DOI":"10.1136\/pgmj.69.808.147","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"147-149","source":"Crossref","is-referenced-by-count":12,"title":["Optochiasmatic tuberculoma causing progressive visual failure: when has medical treatment failed?"],"prefix":"10.1093","volume":"69","author":[{"given":"Wai S","family":"Poon","sequence":"first","affiliation":[{"name":"Departments of Departments of Surgery"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Departments of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong , Shatin, N. T., Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A K C","family":"Li","sequence":"additional","affiliation":[{"name":"Departments of Departments of Surgery"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1993,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0140-6736(80)92953-0","article-title":"Cerebral tuberculomas developing during treatment of tuberculous meningitis","volume":"2","author":"Lebas, J.; Malkin, J.E.; Coquin, Y.","year":"1980","unstructured":"Lebas, J., Malkin, J.E., Coquin, Y. et al. Cerebral tuberculomas developing during treatment of tuberculous meningitis. Lancet 1980, 2: 84.","journal-title":"Lancet"},{"key":"ref_2","first-page":"104","article-title":"Intracranial tuberculomas: correlation of computerised tomography with clinicopathological findings","author":"Loizou, L.A.; Anderson, M.","year":"1982","unstructured":"Loizou, L.A. & Anderson, M. Intracranial tuberculomas: correlation of computerised tomography with clinicopathological findings. Q J Med 1982, 201: 104-114.","journal-title":"Q J Med"},{"key":"ref_3","first-page":"449","article-title":"Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature","volume":"241","author":"Teoh, R.; Humphries, M.J.; O'Mahony, G.","year":"1987","unstructured":"Teoh, R., Humphries, M.J. & O'Mahony, G. Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature. Q J Med 1987, 241: 449-460.","journal-title":"Q J Med"},{"issue":"235","key":"ref_4","first-page":"321","article-title":"Suprasellar tuberculoma developing during treatment of tuberculous meningitis requiring urgent surgical decompression","volume":"1988","author":"Teoh, R.; Poon, W.; Humphries, M.J.","unstructured":"Teoh, R., Poon, W., Humphries, M.J. et al. Suprasellar tuberculoma developing during treatment of tuberculous meningitis requiring urgent surgical decompression. J Neurol 1988, 235: 321-322.","journal-title":"J Neurol"},{"issue":"12","key":"ref_5","first-page":"595","article-title":"Tuberculome du nerf optique","volume":"1966","author":"Delandsheer, J.M.; Dupont, A.; Christiaens, J.L.","unstructured":"Delandsheer, J.M., Dupont, A. & Christiaens, J.L. Tuberculome du nerf optique. Neurochirurgie 1966, 12: 595-599.","journal-title":"Neurochirurgie"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3171\/jns.1980.52.1.0129","article-title":"Tuberculoma ofthe anterior optic pathways, case report","volume":"52","author":"Iraci, G.; Giordano, R.; Derosa, M.","year":"1980","unstructured":"Iraci, G., Giordano, R., Derosa, M. et al. Tuberculoma ofthe anterior optic pathways, case report. J Neurosurg 1980, 52: 129-133.","journal-title":"J Neurosurg"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1136\/jnnp.50.3.360","article-title":"A pituitary tuberculoma","volume":"50","author":"Eckland, D.J.A.; O'Neill, J.H.; Lightman, S.L.","year":"1987","unstructured":"Eckland, D.J.A., O'Neill, J.H. & Lightman, S.L. A pituitary tuberculoma. J Neurol Neurosurg Psychiat 1987, 50: 360-361.","journal-title":"J Neurol Neurosurg Psychiat"},{"issue":"60","key":"ref_8","first-page":"1185","article-title":"Tuberculomes chiasmatiques. Deux observations","volume":"1984","author":"Lesoin, F.; Dubois, F.; Rousseaux, M.","unstructured":"Lesoin, F., Dubois, F., Rousseaux, M. et al. Tuberculomes chiasmatiques. Deux observations. Semin Hop Paris 1984, 60: 1185-1188.","journal-title":"Semin Hop Paris"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1001\/archopht.1971.00990050077011","article-title":"Tuberculoma of the left optic nerve and chiasm","volume":"85","author":"Schlernitzauer, D.A.; Hodges, F.J.; Bagan, M.","year":"1971","unstructured":"Schlernitzauer, D.A., Hodges, F.J. & Bagan, M. Tuberculoma of the left optic nerve and chiasm. Arch Ophthalmol 1971, 85: 75-78.","journal-title":"Arch Ophthalmol"},{"key":"ref_10","first-page":"149","article-title":"Immune reactions in tuberculosis. Lancet 1984, 1: 204","volume":"69","author":"Editorial","year":"1993","unstructured":"Editorial. Immune reactions in tuberculosis. Lancet 1984, 1: 204. Postgrad Med J (1993) 69, 149-150","journal-title":"Postgrad Med J"},{"key":"ref_11","article-title":"The Fellowship of Postgraduate","year":"1993","unstructured":"\u00a9) The Fellowship of Postgraduate Medicine, 1993","journal-title":"Medicine"},{"key":"ref_12","article-title":"In 1911 Oppenheim summarized his experiences of 'the different types of multiple sclerosis'. Among these he described the occurrence of 'sudden numbness and awkwardness of one arm' in which 'the sense of posture is most seriously affected'; he suggested that 'this apparent acute posterior myelitis cervicalis is but a stage of disseminated sclerosis'.' This clinical sign has become referred to as the 'useless hand of Oppenheim' and we report a patient in whom the site of the lesion responsible has been demonstrated","unstructured":"In 1911 Oppenheim summarized his experiences of 'the different types of multiple sclerosis'. Among these he described the occurrence of 'sudden numbness and awkwardness of one arm' in which 'the sense of posture is most seriously affected'; he suggested that 'this apparent acute posterior myelitis cervicalis is but a stage of disseminated sclerosis'.' This clinical sign has become referred to as the 'useless hand of Oppenheim' and we report a patient in whom the site of the lesion responsible has been demonstrated."},{"key":"ref_13","article-title":"Aberdeen AB9 2ZB, UK","volume-title":"mus was also noted. Subsequent sensory disturbances in the limbs and episodes of leg weakness led to a clinical diagnosis of multiple sclerosis, supported by bilaterally delayed visual evoked responses and raised cerebrospinal fluid immunoglobulin concentrations. The current symptoms had begun with numbness of the left hand spreading over a few days to affect the left arm, trunk and leg. He then lost all use of his left hand and involuntary movements developed","author":"Correspondence, R.J.Coleman; D., M.; P., M.R.C.; of Neurology, Department; Infirmary, Aberdeen Royal; Foresterhill","year":"1992","unstructured":"Correspondence: R.J. Coleman, M.D., M.R.C.P., Department of Neurology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB9 2ZB, UK. Accepted: 24 August 1992 mus was also noted. Subsequent sensory disturbances in the limbs and episodes of leg weakness led to a clinical diagnosis of multiple sclerosis, supported by bilaterally delayed visual evoked responses and raised cerebrospinal fluid immunoglobulin concentrations. The current symptoms had begun with numbness of the left hand spreading over a few days to affect the left arm, trunk and leg. He then lost all use of his left hand and involuntary movements developed."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/69\/808\/147\/50072609\/postgradmedj-69-147.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/69\/808\/147\/50072609\/postgradmedj-69-147.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T19:18:49Z","timestamp":1682536729000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/69\/808\/147\/7062774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,2,1]]},"references-count":13,"journal-issue":{"issue":"808","published-online":{"date-parts":[[1993,2,1]]},"published-print":{"date-parts":[[1993,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.69.808.147","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1993,2]]},"published":{"date-parts":[[1993,2,1]]}}}