{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T14:31:20Z","timestamp":1759847480884},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"810","license":[{"start":{"date-parts":[[1993,4,1]],"date-time":"1993-04-01T00:00:00Z","timestamp":733622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,4,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The case of a 32 year old male with normal male adrenarchal hair pattern, bilateral gynaecomastia, a small phallus, hypospadias and bilateral poorly developed testes presenting with primary infertility secondary to azoospermia and a pelvic cyst is described. Repeated chromosomal analysis showed 46XX chromosomal constitution. Laparotomy revealed a simple cyst between the urinary bladder and the rectum.<\/jats:p>\n               <jats:p>XX male syndrome is a rare cause of male infertility. The majority of cases is due to interchange of a fragment of the short arm of the Y chromosome containing the region that encodes the testes determining factor with the X chromosome. The presence of a simple cyst in the anatomical location of the uterus to our knowledge has not been reported in the literature.<\/jats:p>","DOI":"10.1136\/pgmj.69.810.315","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"315-317","source":"Crossref","is-referenced-by-count":8,"title":["Primary infertility in a phenotypic male with 46XX chromosomal constitution"],"prefix":"10.1093","volume":"69","author":[{"given":"T T","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Medicine, Universiti Kebangsaan Malaysia , Jalan Raja Muda, 50300 Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B A K","family":"Khalid","sequence":"additional","affiliation":[{"name":"Department of Medicine, Universiti Kebangsaan Malaysia , Jalan Raja Muda, 50300 Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,4,1]]},"reference":[{"issue":"12","key":"ref_1","first-page":"25","article-title":"XX sex chromosome in a human male: first case","volume":"1964","author":"de la Chapelle, A.; Hartling, H.; Niemi, M.","unstructured":"de la Chapelle, A., Hartling, H., Niemi, M. et al. XX sex chromosome in a human male: first case. Acta Med Scand 1964, 12 (Suppl 4): 25-38.","journal-title":"Acta Med Scand"},{"key":"ref_2","first-page":"71","article-title":"Analytic review: nature and origin of males with XX sex chromosomes","volume":"24","author":"de la Chapelle, A.","year":"1972","unstructured":"de la Chapelle, A. Analytic review: nature and origin of males with XX sex chromosomes. Am J Hum Genet 1972, 24: 71-105.","journal-title":"Am J Hum Genet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00273626","article-title":"Incidence of chromosome aberrations among 11,148 newborn children","volume":"30","author":"Nielsen, J.; Sillesen, I.","year":"1975","unstructured":"Nielsen, J. & Sillesen, I. Incidence of chromosome aberrations among 11,148 newborn children. 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Hum Genet 1981, 58: 105-116.","journal-title":"Hum Genet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/000992289103000103","article-title":"Clinical mangement issues in males with sex chromosomal mosaicism and discordant phenotype\/sex chromosome patterns","volume":"30","author":"van Dyke, D.C.; Hanson, J.W.; Moore, J.W.; Patil, S.R.; Hawtrey, C.E.; Hansen, J.R.","year":"1991","unstructured":"van Dyke, D.C., Hanson, J.W., Moore, J.W., Patil, S.R., Hawtrey, C.E. & Hansen, J.R. Clinical mangement issues in males with sex chromosomal mosaicism and discordant phenotype\/sex chromosome patterns. Cliu Pediatr 1991, 30: 15-21.","journal-title":"Cliu Pediatr"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/0092-8674(87)90535-6","article-title":"An abnormal terminal X-Y interchange accounts for most but not all cases of human XX maleness","volume":"49","author":"Petit, C.; de la Chapelle, A.; Levilliers, J.","year":"1987","unstructured":"Petit, C., de la Chapelle, A., Levilliers, J. et al. An abnormal terminal X-Y interchange accounts for most but not all cases of human XX maleness. Cell 1987, 49: 595-602.","journal-title":"Cell"},{"issue":"14","key":"ref_8","first-page":"1325","article-title":"Moderately repeated DNA sequences specific for the short arm of the human Y chromosome age present in XX males and reduced in copy number in an XY female","volume":"1986","author":"Muller, U.; Lalande, M.; Donlon, T.","unstructured":"Muller, U., Lalande, M., Donlon, T. et al. Moderately repeated DNA sequences specific for the short arm of the human Y chromosome age present in XX males and reduced in copy number in an XY female. Nucl Acids Res 1986, 14: 1325-1340.","journal-title":"Nucl Acids Res"},{"issue":"14","key":"ref_9","first-page":"5375","article-title":"Variable transfer of Y-specific sequences in XX males","volume":"1986","author":"Affara, N.A.; Ferguson-Smith, M.A.; Talmie, J.","unstructured":"Affara, N.A., Ferguson-Smith, M.A., Talmie, J. et al. Variable transfer of Y-specific sequences in XX males. Nucl Acids Res 1986, 14: 5375-5387.","journal-title":"Nucl Acids Res"},{"issue":"223","key":"ref_10","first-page":"786788","article-title":"Chromosome Y-specific DNA is transferred to the short arm of the X chromosome in human XX males","volume":"1986","author":"Andersson, M.; Page, D.C.; de la Chapelle, A.","unstructured":"Andersson, M., Page, D.C. & de la Chapelle, A. Chromosome Y-specific DNA is transferred to the short arm of the X chromosome in human XX males. Science 1986, 223: 786788.","journal-title":"Science"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/328437a0","article-title":"Y-chromosomal short arms in human XX males","volume":"328","author":"Page, D.C.; Brown, L.G.; de la Chapelle, A.Exchange of terminal portions of X.-and","year":"1987","unstructured":"Page, D.C., Brown, L.G. & de la Chapelle, A. Exchange of terminal portions of X-and Y-chromosomal short arms in human XX males. Nature 1987, 328: 437-440.","journal-title":"Nature"},{"key":"ref_12","first-page":"853","article-title":"Disorders of sex differentiation","volume-title":"Williams Textbook of Endocrinology","author":"Grumbach, M.M.; Conte, F.A.","year":"1992","unstructured":"Grumbach, M.M. & Conte, F.A. Disorders of sex differentiation. In: Wilson, J.D. & Foster, D.W. (eds) Williams Textbook of Endocrinology. W.B. Saunders, Philadelphia, 1992, pp. 853-951."}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/69\/810\/315\/50072829\/postgradmedj-69-315.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/69\/810\/315\/50072829\/postgradmedj-69-315.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T12:44:22Z","timestamp":1682599462000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/69\/810\/315\/7062730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4,1]]},"references-count":12,"journal-issue":{"issue":"810","published-online":{"date-parts":[[1993,4,1]]},"published-print":{"date-parts":[[1993,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.69.810.315","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1993,4]]},"published":{"date-parts":[[1993,4,1]]}}}