{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:55:14Z","timestamp":1760982914248},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"816","license":[{"start":{"date-parts":[[1993,10,1]],"date-time":"1993-10-01T00:00:00Z","timestamp":749433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,10,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We describe a 30 year old woman who presented with thyroid storm. She had non-specific symptoms and few clinical signs of hyperthyroidism despite markedly raised thyroid hormone concentrations. Soon after admission her behaviour became abnormal and her level of consciousness deteriorated. Despite the rapid restoration of thyroid hormone concentrations to normal using conventional therapies, and correction of hypoxia resulting from acute pulmonary oedema, her level of consciousness did not improve. Cranial CT scanning revealed extensive bilateral basal ganglia infarction, a previously unreported complication of thyroid storm. This observation suggests that thyroid storm may predispose to hypoxic neurological damage.<\/jats:p>","DOI":"10.1136\/pgmj.69.816.813","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"813-815","source":"Crossref","is-referenced-by-count":11,"title":["Thyroid storm in a young woman resulting in bilateral basal ganglia infarction"],"prefix":"10.1093","volume":"69","author":[{"given":"S R","family":"Page","sequence":"first","affiliation":[{"name":"Department of Medicine, Derbyshire Royal Infirmary , London Road, Derby DE1 2QY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A R","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Medicine, Derbyshire Royal Infirmary , London Road, Derby DE1 2QY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,10,1]]},"reference":[{"issue":"52","key":"ref_1","first-page":"626","article-title":"A clinical study of thyroid storm","volume":"1960","author":"Waldstein, S.S.; Slodki, M.D.; Kaganiec, G.I.","unstructured":"Waldstein, S.S., Slodki, M.D., Kaganiec, G.I. et al. A clinical study of thyroid storm. Ann Intern Med 1960, 52: 626-642.","journal-title":"Ann Intern Med"},{"issue":"124","key":"ref_2","first-page":"684","article-title":"Thyroid storm: a review of 22 episodes with special emphasis on the use of guanethidine","volume":"1969","author":"Mazzaferri, E.L.; Skillman, T.G.","unstructured":"Mazzaferri, E. L. & Skillman, T.G. Thyroid storm: a review of 22 episodes with special emphasis on the use of guanethidine. Arch Intern Med 1969, 124: 684-690.","journal-title":"Arch Intern Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1001\/archinte.1980.00330200070023","article-title":"Behavioral function in hyperthyroidism. Improvement with treatment","volume":"140","author":"Rockey, P.H.; Grief, R.J.","year":"1980","unstructured":"Rockey, P.H. & Grief, R.J. Behavioral function in hyperthyroidism. Improvement with treatment. Arch Intern Med 1980, 140: 1194-1197.","journal-title":"Arch Intern Med"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1528-1157.1980.tb04048.x","article-title":"Seizures in thyrotoxicosis","volume":"21","author":"Jabbari, B.; Huott, A.D.","year":"1980","unstructured":"Jabbari, B. & Huott, A.D. Seizures in thyrotoxicosis. Epilepsia 1980, 21: 91-96.","journal-title":"Epilepsia"},{"key":"ref_5","first-page":"297","article-title":"Hyperthyroidism presenting as pyramidal tract disease","volume":"1988","author":"Shaw, P.J.; Bates, D.; Kendall-Taylor, P.","unstructured":"Shaw, P.J., Bates, D. & Kendall-Taylor, P. Hyperthyroidism presenting as pyramidal tract disease. Br Med J 1988, 297: 1395-1396.","journal-title":"Br Med J"},{"issue":"6","key":"ref_6","first-page":"453","article-title":"Paroxysmal choreoathetosis associated with thyrotoxicosis","volume":"1979","author":"Fishbeck, K.H.; Layzer, R.B.","unstructured":"Fishbeck, K.H. & Layzer, R.B. Paroxysmal choreoathetosis associated with thyrotoxicosis. Ann Neurol 1979,6:453-454.","journal-title":"Ann Neurol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/0306-4522(83)90121-5","article-title":"Effect of thyroid state on serotonin, 5-hydroxyindolacetic acid and substance P contents in discrete brain nuclei of adult rats","volume":"10","author":"Savard, P.; Merand, Y.; Dipaolo, T.","year":"1983","unstructured":"Savard, P., Merand, Y., Dipaolo, T. et al. Effect of thyroid state on serotonin, 5-hydroxyindolacetic acid and substance P contents in discrete brain nuclei of adult rats. 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J Neural Transmission 1984, 59: 43-55.","journal-title":"J Neural Transmission"},{"key":"ref_9","first-page":"311","article-title":"Effect ofexperimental changes in thyroid function on oxidative metabolism and glutamate dehydrogenase activity in the limbic system of the rat","volume":"39","author":"Fernandez-Pastor, J.M.; Morrel, M.; Menendez-Patterson, A.","year":"1983","unstructured":"Fernandez-Pastor, J.M., Morrel, M., Menendez-Patterson, A. et al. Effect ofexperimental changes in thyroid function on oxidative metabolism and glutamate dehydrogenase activity in the limbic system of the rat. Rev Espanol Fisiol 1983, 39: 311-316.","journal-title":"Rev Espanol Fisiol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1159\/000459084","article-title":"Changes of pyruvate dehydrogenase in rat brain with thyroid hormones","volume":"28","author":"Murthy, A.S.; Baquer, N.Z.","year":"1982","unstructured":"Murthy, A.S. & Baquer, N.Z. Changes of pyruvate dehydrogenase in rat brain with thyroid hormones. Enzyme 1982, 28: 48-53.","journal-title":"Enzyme"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1001\/archneur.1983.04050070063016","article-title":"Delayed neurological sequelae in carbon monoxide intoxication","volume":"40","author":"Choi, H.S.","year":"1983","unstructured":"Choi, H.S. Delayed neurological sequelae in carbon monoxide intoxication. Arch Neurol 1983, 40: 433-435.","journal-title":"Arch Neurol"},{"key":"ref_12","first-page":"177","article-title":"Cerebral computed tomography in drowning victims","volume":"5","author":"Murray, R.R.; Kapila, A.; Blanco, E.","year":"1984","unstructured":"Murray, R.R., Kapila, A., Blanco, E. et al. Cerebral computed tomography in drowning victims. Am J Neuroradiol 1984, 5: 177-179.","journal-title":"Am J Neuroradiol"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1001\/archneur.1991.00530200113030","article-title":"Delayed post-anoxic encephalopathy after strangulation: serial neuroradiological and neurochemical studies","volume":"48","author":"Hori, A.; Hirose, G.; Kataoka, S.; Tsukada, K.; Furui, K.; Tonami, H.","year":"1991","unstructured":"Hori, A., Hirose, G., Kataoka, S., Tsukada, K., Furui, K. & Tonami, H. Delayed post-anoxic encephalopathy after strangulation: serial neuroradiological and neurochemical studies. Arch Neurol 1991, 48: 871-874.","journal-title":"Arch Neurol"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1056\/NEJM197510162931607","article-title":"Neurotransmitters and the normal and ischemic cerebral circulation","volume":"293","author":"Zervas, N.T.; Lavyne, M.H.; Negoro, M.","year":"1975","unstructured":"Zervas, N.T., Lavyne, M.H. & Negoro, M. 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J Am Med Assoc 1978, 240: 2567-2568.","journal-title":"J Am Med Assoc"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/ana.410140615","volume":"14","author":"Newcomer, J.; Haire, W.; Hartman, C.R.Coma; thyrotoxicosis","year":"1983","unstructured":"Newcomer, J., Haire, W. & Hartman, C.R. Coma and thyrotoxicosis. Ann Neurol 1983, 14: 689-690.","journal-title":"Ann Neurol"},{"key":"ref_18","first-page":"571","article-title":"Thyroid storm presenting with coma and seizures in a 3-year old girl. Clin Pediat","volume":"28","author":"Aiello, D.P.; DuPlessis, A.J.; Pattishall, E.G.; Kulin, H.E.","year":"1989","unstructured":"Aiello, D.P., DuPlessis, A.J., Pattishall, E.G. & Kulin, H.E. Thyroid storm presenting with coma and seizures in a 3-year old girl. Clin Pediat 1989, 28: 571-574."},{"key":"ref_19","first-page":"353","volume":"75","author":"McDermott, M.T.; Kidd, G.S.; Dodson, L.E.","year":"1983","unstructured":"McDermott, M.T., Kidd, G.S., Dodson, L.E. et al. Radioiodine-induced thyroid storm. Am J Med 1983, 75: 353-359.","journal-title":"et al. Radioiodine-induced thyroid storm. Am J Med"},{"issue":"1","key":"ref_20","first-page":"77","article-title":"Thyroid emergencies","volume-title":"Bailliere's Clinical Endocrinology and Metabolism","volume":"6","author":"Burger, A.G.; Philippe, J.","year":"1992","unstructured":"Burger, A.G. & Philippe, J. Thyroid emergencies. In: Burger, A.G. & Philippe, J. (eds) Bailliere's Clinical Endocrinology and Metabolism, Vol. 6, no. 1, Endocrine Emergencies. W.B. Saunders, London, 1992, pp. 77-93."},{"issue":"22","key":"ref_21","first-page":"489","article-title":"Comparative effects of sodium iopodate and iodide on serum thyroid hormone concentrations in patients with Graves'","volume":"1985","author":"Roti, E.; Robushi, G.; Manfredi, A.","unstructured":"Roti, E., Robushi, G., Manfredi, A. et al. Comparative effects of sodium iopodate and iodide on serum thyroid hormone concentrations in patients with Graves' disease. Clinical Endocrinol 1985, 22: 489-496.","journal-title":"disease. 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