{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T11:29:00Z","timestamp":1775561340105,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"819","license":[{"start":{"date-parts":[[1994,1,1]],"date-time":"1994-01-01T00:00:00Z","timestamp":757382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A prospective study of 65 patients with perforated typhoid enteritis managed operatively over a 3 year period at a university hospital is presented. There were 45 males and 20 females with ages ranging from 5 to 15 years. Presenting symptoms were fever, abdominal pain, vomiting and either diarrhoea or constipation. All the patients were subjected to surgery and 56 (86%) underwent two-layer bowel closure after freshening of ulcer margins. The overall mortality rate in this study was 20% and was adversely influenced by the increasing duration of perforation, presence of shock and faecal peritonitis.<\/jats:p>\n               <jats:p>Early surgery after prompt and adequate resuscitation is life saving. However, prevention of typhoid fever by providing safe drinking water and better sanitary conditions appears to offer the best chance of decreasing the high rates of mortality and morbidity of this deadly disease.<\/jats:p>","DOI":"10.1136\/pgmj.70.819.19","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"19-22","source":"Crossref","is-referenced-by-count":10,"title":["Perforated typhoid enteritis in children"],"prefix":"10.1093","volume":"70","author":[{"given":"Vineeta","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Banaras Hindu University , Varanasi-221005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev K","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Medical Sciences, Banaras Hindu University , Varanasi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay K","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Medical Sciences, Banaras Hindu University , Varanasi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saroj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Medical Sciences, Banaras Hindu University , Varanasi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/bjs.1800690321","article-title":"Typhoid enteric perforation","volume":"69","author":"Chouhan, M.K.; Pandu, S.K.","year":"1982","unstructured":"Chouhan, M.K. & Pandu, S.K. Typhoid enteric perforation. Br J Surg 1982, 69: 173-175.","journal-title":"Br J Surg"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0002-9610(89)90591-6","article-title":"Perforated typhoid enteritis: operative experience with 108 cases","volume":"157","author":"Meier, D.E.; Imediegwu, O.O.; Tarpley, J.L.","year":"1989","unstructured":"Meier, D.E., Imediegwu, O.O. & Tarpley, J.L. Perforated typhoid enteritis: operative experience with 108 cases. Am J Surg 1989, 157: 423-427.","journal-title":"Am J Surg"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1002\/bjs.1800760905","volume":"76","author":"Gibney, E.J.Typhoid perforation","year":"1989","unstructured":"Gibney, E.J. Typhoid perforation. 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J Trop Med Hyg 1977, 80: 83-87.","journal-title":"J Trop Med Hyg"},{"key":"ref_11","first-page":"227","article-title":"Surgical treatment of typhoid perforation. Experience of 1976 Sangli epidemic","volume":"40","author":"Puroshit, P.G.","year":"1978","unstructured":"Puroshit, P.G. Surgical treatment of typhoid perforation. Experience of 1976 Sangli epidemic. Indian J Surg 1978, 40: 227-238.","journal-title":"Indian J Surg"},{"key":"ref_12","first-page":"643","article-title":"The problem of enteric ileal perforation (experience of 112 cases)","volume":"41","author":"Swadia, N.D.; Trivedi, P.M.; Thakkar, A.M.","year":"1979","unstructured":"Swadia, N.D., Trivedi, P.M. & Thakkar, A.M. The problem of enteric ileal perforation (experience of 112 cases). 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