{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T11:40:30Z","timestamp":1684150830023},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"821","license":[{"start":{"date-parts":[[1994,3,1]],"date-time":"1994-03-01T00:00:00Z","timestamp":762480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,3,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We report a case of late-onset isolated thyroid stimulating hormone deficiency in a woman who presented with oligomenorrhoea and secondary hyperprolactinaemia. Hypothalamic and pituitary radiology and function was otherwise normal. The underlying aetiology of this condition is thought to be due to an inborn defect in the thyrotroph and treatment is with standard thyroid replacement therapy.<\/jats:p>","DOI":"10.1136\/pgmj.70.821.225","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"225-227","source":"Crossref","is-referenced-by-count":2,"title":["A case of isolated TSH deficiency presenting as infertility"],"prefix":"10.1093","volume":"70","author":[{"given":"Adam H","family":"Balen","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Cobbold Laboratories, The Middlesex Hospital , Mortimer Street, London W1N 8AA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J","family":"Manning","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Cobbold Laboratories, The Middlesex Hospital , Mortimer Street, London W1N 8AA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1994,3,1]]},"reference":[{"key":"ref_1","first-page":"165","article-title":"Thyroid autoregulation: impact on thyroid structure and function in rats","volume":"16","author":"Penel, C.; Rognoni, J.B.; Bastiani, P.","year":"1987","unstructured":"Penel, C., Rognoni, J.B. & Bastiani, P. Thyroid autoregulation: impact on thyroid structure and function in rats. Am J Physiol 1987, 16: E165-E172.","journal-title":"Am J Physiol"},{"key":"ref_2","first-page":"356","article-title":"Thyroid of the newborn and postnatal iodine overload","volume":"36","author":"Castaing, H.; Fournet, J.P.; Leger, F.A.","year":"1979","unstructured":"Castaing, H., Fournet, J.P., Leger, F.A. et al. Thyroid of the newborn and postnatal iodine overload. Arch Franc Pediat 1979, 36: 356-358.","journal-title":"Arch Franc Pediat"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0950-351X(89)80046-1","article-title":"Development of the thyroid","volume":"3","author":"Fisher, D.A.; Polk, D.H.","year":"1989","unstructured":"Fisher, D.A. & Polk, D.H. Development of the thyroid. In: Jones, C.T. (ed.) Perinatal Endocrinology. Bailliere's Clinical Endocrinology & Metabolism, Vol. 3, 1989, pp. 627-658.","journal-title":"Bailliere's Clinical Endocrinology & Metabolism; Perinatal Endocrinology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1056\/NEJM197111042851902","article-title":"Familial isolated thyrotrophin deficiency with cretinism","volume":"285","author":"Miyai, K.; Azukizawa, M.; Kumahara, Y.","year":"1971","unstructured":"Miyai, K., Azukizawa, M. & Kumahara, Y. Familial isolated thyrotrophin deficiency with cretinism. N Engl J Med 1971, 285: 1043-1048.","journal-title":"N Engl J Med"},{"issue":"23","key":"ref_5","first-page":"675","article-title":"Familial growth retardation with isolated thyroid-stimulating hormone deficiency","volume":"1984","author":"Labbe, A.; Dubray, C.; Gaillard, G.; Besse, G.; Assali, P.; Malpuech, G.","unstructured":"Labbe, A., Dubray, C., Gaillard, G., Besse, G., Assali, P. & Malpuech, G. Familial growth retardation with isolated thyroid-stimulating hormone deficiency. Clin Pediat 1984, 23: 675-678.","journal-title":"Clin Pediat"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1002\/j.1460-2075.1989.tb08355.x","article-title":"Thyroid stimulating hormone deficiency caused by a single base substitution in the CAGYC region of the beta-subunit","volume":"8","author":"Hayashizaki, Y.; Hiraoka, Y.; Endo, Y.; Miyai, K.; Matsubara, K.","year":"1989","unstructured":"Hayashizaki, Y., Hiraoka, Y., Endo, Y., Miyai, K. & Matsubara, K. Thyroid stimulating hormone deficiency caused by a single base substitution in the CAGYC region of the beta-subunit. EMBO J 1989, 8: 2291-2296.","journal-title":"EMBO J"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/BF01883604","article-title":"Rapid detection of a point mutation in thyroid-stimulating hormone beta-subunit gene causing congenital isolated thyroid-stimulating hormone deficiency","volume":"36","author":"Mori, R.; Sawai, T.; Kinoshita, E.","year":"1991","unstructured":"Mori, R., Sawai, T., Kinoshita, E. et al. Rapid detection of a point mutation in thyroid-stimulating hormone beta-subunit gene causing congenital isolated thyroid-stimulating hormone deficiency. Jinrui Idengaku Zasshi 1991, 36: 313-316.","journal-title":"Jinrui Idengaku Zasshi"},{"issue":"35","key":"ref_8","first-page":"517","article-title":"Serum free thyrotrophin subunit in congenital isolated thyrotrophin deficiency","volume":"1988","unstructured":"Miyai, K., Endo, Y., lijima, Y., Kabutomori, 0. & Hayashizaki, Y. Serum free thyrotrophin subunit in congenital isolated thyrotrophin deficiency. Endocrinol Jap 1988, 35: 517-521.","journal-title":"Endocrinol Jap"},{"issue":"13","key":"ref_9","first-page":"795","article-title":"Hypothyroidism due to thyrotropin deficiency without other manifestations of hypopituitarism","volume":"1953","author":"Shuman, C.R.","unstructured":"Shuman, C.R. Hypothyroidism due to thyrotropin deficiency without other manifestations of hypopituitarism. J Clin Endocrino Metab 1953, 13: 795-800.","journal-title":"J Clin Endocrino Metab"},{"key":"ref_10","first-page":"176","article-title":"Isolated deficiencies of anterior pituitary hormones","author":"Odell, W.D.","year":"1966","unstructured":"Odell, W.D. Isolated deficiencies of anterior pituitary hormones. JAMA 1966, 197: 176-186.","journal-title":"JAMA"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1177\/014107687907200505","article-title":"Isolated ACTH deficiency and TSH deficiency in the adult","volume":"72","author":"Burke, C.W.; Moore, R.A.; Rees, L.H.; Bottazo, G.F.; Mashiter, K.; Bitensky, L.","year":"1979","unstructured":"Burke, C.W., Moore, R.A., Rees, L.H., Bottazo, G.F., Mashiter, K. & Bitensky, L. Isolated ACTH deficiency and TSH deficiency in the adult. J R Soc Med 1979, 72: 328-335.","journal-title":"J R Soc Med"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF03348429","article-title":"Hypothalamic hypothyroidism due to isolated thyrotropinreleasing hormone (TRH) deficiency","volume":"7","author":"Katakami, H.; Kato, Y.; Inada, M.; Imura, H.","year":"1984","unstructured":"Katakami, H., Kato, Y., Inada, M. & Imura, H. Hypothalamic hypothyroidism due to isolated thyrotropinreleasing hormone (TRH) deficiency. J Endocrinol Invest 1984, 7: 231-233.","journal-title":"J Endocrinol Invest"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1056\/NEJM197211092871909","article-title":"Prolactin stimulation by thyrotropin-releasing hormone in a patient with isolated thyrotrophin deficiency","volume":"287","author":"Sachson, R.; Rosen, S.W.; Cuatrecasas, P.; Roth, J.; Frantz, A.G.","year":"1972","unstructured":"Sachson, R., Rosen, S.W., Cuatrecasas, P., Roth, J. & Frantz, A.G. Prolactin stimulation by thyrotropin-releasing hormone in a patient with isolated thyrotrophin deficiency. N Engl J Med 1972, 287: 972-975.","journal-title":"N Engl J Med"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0002-9343(87)90515-8","article-title":"Primary idiopathic hypothalamic hypothyroidism","volume":"83","author":"Gharin, H.; Abboud, C.F.","year":"1987","unstructured":"Gharin, H. & Abboud, C.F. Primary idiopathic hypothalamic hypothyroidism. Am J Med 1987, 83: 171-174.","journal-title":"Am J Med"},{"key":"ref_15","first-page":"97","article-title":"Prolactin disorders in infertility","author":"Blackwell, R.E.; Chang, R.J.; Cragun, J.R.","year":"1990","unstructured":"Blackwell, R.E., Chang, R.J. & Cragun, J.R. Prolactin disorders in infertility. In: Seibel, M.M. (ed.) Infertility - A Comprehensive Text. Appleton & Lange, Connecticut, 1990, pp.97-110.","journal-title":"Appleton & Lange, Connecticut; Infertility - A Comprehensive Text"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/70\/821\/225\/50217617\/postgradmedj-70-225.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/70\/821\/225\/50217617\/postgradmedj-70-225.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T11:03:14Z","timestamp":1684148594000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/70\/821\/225\/7042349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,3,1]]},"references-count":15,"journal-issue":{"issue":"821","published-online":{"date-parts":[[1994,3,1]]},"published-print":{"date-parts":[[1994,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.70.821.225","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1994,3]]},"published":{"date-parts":[[1994,3,1]]}}}