{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:41:03Z","timestamp":1787168463236,"version":"build-2736575974"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"825","license":[{"start":{"date-parts":[[1994,7,1]],"date-time":"1994-07-01T00:00:00Z","timestamp":773020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1994,7,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious disease suggested the presence of a neoplasm. The gynaecological sonogram showed a solid mass located behind the uterus. Laparotomy confirmed a poorly differentiated ovarian carcinoma. The association of systemic amyloidosis and ovarian carcinoma has not to our knowledge been described previously.<\/jats:p>","DOI":"10.1136\/pgmj.70.825.505","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T16:25:21Z","timestamp":1230567921000},"page":"505-506","source":"Crossref","is-referenced-by-count":12,"title":["Systemic amyloidosis and ovarian carcinoma"],"prefix":"10.1093","volume":"70","author":[{"given":"C","family":"Fernandez-Miranda","sequence":"first","affiliation":[{"name":"Department of Medicine and Pathology , Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Mateo","sequence":"additional","affiliation":[{"name":"Department of Medicine and Pathology , Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Gonzalez-Gomez","sequence":"additional","affiliation":[{"name":"Department of Medicine and Pathology , Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Ballestin","sequence":"additional","affiliation":[{"name":"Department of Medicine and Pathology , Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1994,7,1]]},"reference":[{"issue":"89","key":"ref_1","first-page":"411","article-title":"Systemic amyloidosis and nonhematologic malignancy in a large autopsy series","volume":"1981","author":"Dictor, M.; Hasserius, R.","unstructured":"Dictor, M. & Hasserius, R. Systemic amyloidosis and nonhematologic malignancy in a large autopsy series. Acta Path Microbiol Scand A 1981, 89: 411-416.","journal-title":"Acta Path Microbiol Scand A"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1177\/32.3.6363521","article-title":"Monoclonal antibodies against fibril protein AA. Production, specificity, and use for immunohistochemical localization and classification of AA-type amyloidosis","volume":"32","author":"Linke, R.P.","year":"1984","unstructured":"Linke, R.P. Monoclonal antibodies against fibril protein AA. Production, specificity, and use for immunohistochemical localization and classification of AA-type amyloidosis. J Histochem Cytochem 1984, 32: 322-328.","journal-title":"J Histochem Cytochem"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0046-8177(83)80016-1","article-title":"Renal cell carcinoma and systemic amyloidosis. Demonstration of AA protein and review of the literature","volume":"14","author":"Vanatta, P.R.; Silva, F.G.; Taylor, W.E.; Costa, J.C.","year":"1983","unstructured":"Vanatta, P.R., Silva, F.G., Taylor, W.E. & Costa, J.C. Renal cell carcinoma and systemic amyloidosis. Demonstration of AA protein and review of the literature. Hum Pathol 1983, 14: 195-201.","journal-title":"Hum Pathol"},{"key":"ref_4","first-page":"225","article-title":"Remission of nephrotic syndrome in amyloidosis associated with a hypernephroma","volume":"32","author":"Tang, A.L.; Davies, D.R.; Wing, A.J.","year":"1989","unstructured":"Tang, A.L., Davies, D.R. & Wing, A.J. Remission of nephrotic syndrome in amyloidosis associated with a hypernephroma. Clin Nephrol 1989, 32: 225-228.","journal-title":"Clin Nephrol"},{"key":"ref_5","first-page":"212","article-title":"Amyloid in polypeptide hormone-producing tumors","volume":"37","author":"Westermark, P.; Grimelius, L.; Polak, J.M.","year":"1977","unstructured":"Westermark, P., Grimelius, L., Polak, J.M. et al. Amyloid in polypeptide hormone-producing tumors. Lab Invest 1977, 37: 212-215.","journal-title":"Lab Invest"},{"issue":"58","key":"ref_6","first-page":"87","article-title":"Interstitial amyloid in pheochromocytomas","volume":"1988","author":"Steinhoff, M.M.; Wells, S.A.; Deschryver-Kecskemeti, K.","unstructured":"Steinhoff, M.M., Wells, S.A. & Deschryver-Kecskemeti, K. Interstitial amyloid in pheochromocytomas. Lab Invest 1988, 58: 87A (abstract).","journal-title":"Lab Invest"},{"key":"ref_7","first-page":"199","article-title":"Amyloid-producing squamous cell carcinoma ofthe uterine cervix","volume":"117","author":"Tsang, W.Y.W.; Chan, J.K.C.","year":"1993","unstructured":"Tsang, W.Y.W. & Chan, J.K.C. Amyloid-producing squamous cell carcinoma ofthe uterine cervix. Arch Pathol Lab Med 1993, 117: 199-201.","journal-title":"Arch Pathol Lab Med"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/70\/825\/505\/50217910\/postgradmedj-70-505.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/70\/825\/505\/50217910\/postgradmedj-70-505.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T07:13:46Z","timestamp":1684134826000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/70\/825\/505\/7042388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,7,1]]},"references-count":7,"journal-issue":{"issue":"825","published-online":{"date-parts":[[1994,7,1]]},"published-print":{"date-parts":[[1994,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.70.825.505","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1994,7]]},"published":{"date-parts":[[1994,7,1]]}}}