{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T22:40:50Z","timestamp":1683758450561},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"831","license":[{"start":{"date-parts":[[1995,1,1]],"date-time":"1995-01-01T00:00:00Z","timestamp":788918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We describe five patients with previous poliomyelitis who developed multiple sclerosis (two laboratory supported definite and three clinically definite). The initial symptoms of functional deterioration developed a mean of 30 years following poliomyelitis. Initial functional deterioration was due to progressive limb weakness or impaired mobility and in three cases this led to an initial diagnosis of post-polio muscular atrophy. The clinical diagnosis became apparent with the subsequent development of characteristic clinical features, including optic nerve, brainstem, cerebellum, and spinal cord involvement. The occurrence of multiple sclerosis in these patients emphasises that late functional deterioration may be apparently unrelated to previous poliomyelitis. Furthermore, characteristic clinical features may be masked by the severe pre-existing neuromuscular and orthopaedic impairment leading to diagnostic delay and confusion with the ill-defined clinical syndrome of progressive post-polio muscular atrophy.<\/jats:p>","DOI":"10.1136\/pgmj.71.831.52","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"52-54","source":"Crossref","is-referenced-by-count":3,"title":["Multiple sclerosis presenting as late functional deterioration after poliomyelitis"],"prefix":"10.1093","volume":"71","author":[{"given":"E","family":"Chroni","sequence":"first","affiliation":[{"name":"Lane-Fox Unit and Departments of Neurophysiology and Neurology, Guy\u2019s and St. Thomas\u2019 Hospital Trust, St Thomas\u2019 Campus , London , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R S","family":"Howard","sequence":"additional","affiliation":[{"name":"Lane-Fox Unit and Departments of Neurophysiology and Neurology, Guy\u2019s and St. Thomas\u2019 Hospital Trust, St Thomas\u2019 Campus , London , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C P","family":"Panayiotopoulos","sequence":"additional","affiliation":[{"name":"Lane-Fox Unit and Departments of Neurophysiology and Neurology, Guy\u2019s and St. Thomas\u2019 Hospital Trust, St Thomas\u2019 Campus , London , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G T","family":"Spencer","sequence":"additional","affiliation":[{"name":"Lane-Fox Unit and Departments of Neurophysiology and Neurology, Guy\u2019s and St. Thomas\u2019 Hospital Trust, St Thomas\u2019 Campus , London , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1995,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1056\/NEJM198604103141505","article-title":"A long-term follow-up study of patients with post-poliomyelitis neuromuscular syndromes","volume":"314","author":"Dalakas, M.C.; Elder, G.; Hallett, M.","year":"1986","unstructured":"Dalakas MC, Elder G, Hallett M, et al. A long-term follow-up study of patients with post-poliomyelitis neuromuscular syndromes. N Engl J Med 1986; 314: 959-63.","journal-title":"N Engl J Med"},{"key":"ref_2","first-page":"219","article-title":"The late sequelae of poliomyelitis","volume":"251","author":"Howard, R.S.; Wiles, C.M.; Spencer, G.T.","year":"1988","unstructured":"Howard RS, Wiles CM, Spencer GT. The late sequelae of poliomyelitis. Q J Med 1988; 251: 219-32.","journal-title":"Q J Med"},{"key":"ref_3","first-page":"1","article-title":"The diagnosis of multiple sclerosis","author":"McDonald, W.I.; Silberberg, D.H.","year":"1986","unstructured":"McDonald WI, Silberberg DH. The diagnosis of multiple sclerosis. In: WI McDonald, DA Silberberg, eds. Multiple sclerosis. London: Butterworth, 1986; pp 1-11."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1136\/bmj.300.6725.631","article-title":"Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study","volume":"300","author":"Thompson, A.J.; Kermode, A.G.; MacManus, D.G.","year":"1990","unstructured":"Thompson AJ, Kermode AG, MacManus DG, et al. Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study. BMJ 1990; 300: 631-4.","journal-title":"BMJ"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1001\/archneur.1988.00520290033010","article-title":"Long term changes in the spinal cords of patients with old poliomyelitis: signs of continuous disease activity","volume":"45","author":"Pezeshkpour, G.H.; Dalakas, M.C.","year":"1988","unstructured":"Pezeshkpour GH, Dalakas MC. Long term changes in the spinal cords of patients with old poliomyelitis: signs of continuous disease activity. Arch Neurol 1988; 45: 505-8.","journal-title":"Arch Neurol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1212\/WNL.42.7.1421","article-title":"Syringomyelia as a late complication of paralytic poliomyelitis","volume":"42","author":"Feve, A.; Wallays, C.; Nicolle, M.H.; Guillard, A.","year":"1992","unstructured":"Feve A, Wallays C, Nicolle MH, Guillard A. Syringomyelia as a late complication of paralytic poliomyelitis. Neurology 1992; 42: 1421-2.","journal-title":"Neurology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1212\/WNL.17.3.213","article-title":"Syringomyelia as a possible complication of poliomyelitis","volume":"17","author":"Carroll, S.D.","year":"1967","unstructured":"Carroll SD. Syringomyelia as a possible complication of poliomyelitis. Neurology 1967; 17: 213-5.","journal-title":"Neurology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/ana.410260604","article-title":"Isoelectric focusing studies ofserum and cerebrospinal fluid in patients with antecedent poliomyelitis","volume":"26","author":"Salazar-Grueso, E.F.; Grimaldi, L.M.E.; Roos, R.P.; Variakojis, R.; Jubelt, B.; Cashman, N.R.","year":"1989","unstructured":"Salazar-Grueso EF, Grimaldi LME, Roos RP, Variakojis R, Jubelt B, Cashman NR. Isoelectric focusing studies ofserum and cerebrospinal fluid in patients with antecedent poliomyelitis. Ann Neurol 1989; 26: 709-13.","journal-title":"Ann Neurol"},{"key":"ref_9","first-page":"215","article-title":"Upper motor neurone (UMN) findings in patients with antecedent poliomyelitis","volume":"37","author":"Salazar-Grueso, E.F.; Cashman, N.R.; Maselli, R.; Roos, R.P.","year":"1987","unstructured":"Salazar-Grueso EF, Cashman NR, Maselli R, Roos RP. Upper motor neurone (UMN) findings in patients with antecedent poliomyelitis. Neurology 1987; 37: 215.","journal-title":"Neurology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0140-6736(88)92129-0","article-title":"Motoneurone disease and postpoliomyelitis in England and Wales","volume":"i:","author":"Martyn, C.N.; Barker, D.J.P.; Osmond, C.","year":"1988","unstructured":"Martyn CN, Barker DJP, Osmond C. Motoneurone disease and postpoliomyelitis in England and Wales. Lancet 1988; i: 1319-22.","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1136\/jnnp.55.12.1116","article-title":"Motor neurone disease and polio in Scotland","volume":"55","author":"Swingler, R.J.; Fraser, H.; Warlow, C.P.","year":"1992","unstructured":"Swingler RJ, Fraser H, Warlow CP. Motor neurone disease and polio in Scotland. J Neurol Neurosurg Psychiatry 1992; 55: 1116-20.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1212\/WNL.40.1.172","article-title":"How frequently does classic amyotrophic lateral sclerosis develop in survivors of poliomyelitis?","volume":"40","year":"1990","unstructured":"Armon C, Daube JR, Windebank AJ, Kurland LT. How frequently does classic amyotrophic lateral sclerosis develop in survivors of poliomyelitis? Neurology 1990; 40: 172-4.","journal-title":"Neurology"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/71\/831\/52\/50218721\/postgradmedj-71-52.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/71\/831\/52\/50218721\/postgradmedj-71-52.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T22:16:31Z","timestamp":1683756991000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/71\/831\/52\/7044119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1,1]]},"references-count":12,"journal-issue":{"issue":"831","published-online":{"date-parts":[[1995,1,1]]},"published-print":{"date-parts":[[1995,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.71.831.52","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1995,1]]},"published":{"date-parts":[[1995,1,1]]}}}