{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T06:41:50Z","timestamp":1792219310611,"version":"4.4.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"835","license":[{"start":{"date-parts":[[1995,5,1]],"date-time":"1995-05-01T00:00:00Z","timestamp":799286400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We report a case of primary haemochromatosis complicated by anterior hypopituitarism which recovered after aggressive venesection therapy. Reversal of anterior hypopituitarism in haemochromatosis following iron depletion has not been previously described.<\/jats:p>","DOI":"10.1136\/pgmj.71.835.297","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"297-298","source":"Crossref","is-referenced-by-count":28,"title":["Hypopituitarism in primary haemochromatosis; recovery after iron depletion"],"prefix":"10.1093","volume":"71","author":[{"given":"R","family":"Gama","sequence":"first","affiliation":[{"name":"Department of Clinical Biochemistry and Nutrition, Royal Surrey County Hospital , Guildford, Surrey , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M J","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Wright","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry and Nutrition, Royal Surrey County Hospital , Guildford, Surrey , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Marks","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry and Nutrition, Royal Surrey County Hospital , Guildford, Surrey , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1995,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00000441-198305000-00002","article-title":"The endocrine manifestations of hemochromatosis","volume":"285","author":"McNeil, L.W.; McKee, L.C.; Lorber, D.; Rabin, D.","year":"1983","unstructured":"McNeil LW, McKee LC, Lorber D, Rabin D. The endocrine manifestations of hemochromatosis. Am J Med Sci 1983; 285: 7-13.","journal-title":"Am J Med Sci"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0002-9343(68)90182-4","article-title":"Pituitary function in haemochromatosis","volume":"45","author":"Stocks, A.E.; Martin, F.I.R.","year":"1968","unstructured":"Stocks AE, Martin FIR. Pituitary function in haemochromatosis. Am J Med 1968; 45: 839-45.","journal-title":"Am J Med"},{"key":"ref_3","first-page":"298","article-title":"Pituitary function in idiopathic haemochromatosis and cirrhosis of the liver","author":"LW, Stocks A.E.Powell","year":"1972","unstructured":"Stocks AE. Powell LW. Pituitary function in idiopathic haemochromatosis and cirrhosis of the liver. Lancet 1972; 298-300.","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1365-2362.1972.tb00666.x","article-title":"Study of somatotrophic and gonadotrophic pituitary function in idiopathic haemochromatosis (31 cases)","volume":"2","author":"Franchimont, M.S.P.; Murie, N.; Ferrand, B.; Van Cauwenberge, H.; Bourel, M.","year":"1972","unstructured":"Franchimont MSP, Murie N, Ferrand B, Van Cauwenberge H, Bourel M. Study of somatotrophic and gonadotrophic pituitary function in idiopathic haemochromatosis (31 cases). Eur J Clin Invest 1972; 2: 384-9.","journal-title":"Eur J Clin Invest"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1530\/acta.0.0980178","article-title":"Pituitary function in idiopathic haemochromatosis: hormonal study in 36 male patients","volume":"98","author":"Charbonnel, B.; Chupin, M.; Le Grand, A.; Guillon, J.","year":"1981","unstructured":"Charbonnel B, Chupin M, Le Grand A, Guillon J. Pituitary function in idiopathic haemochromatosis: hormonal study in 36 male patients. Acta Endocrinol 1981; 98: 178-83.","journal-title":"Acta Endocrinol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1210\/jcem-43-4-866","article-title":"A study of pituitary function in patients with idiopathic hemochromatosis","volume":"43","author":"Walsh, C.H.; Wright, A.D.; Williams, J.W.; Holder, G.","year":"1976","unstructured":"Walsh CH, Wright AD, Williams JW, Holder G. A study of pituitary function in patients with idiopathic hemochromatosis. J Clin Endocrinol Metab 1976; 43: 866-72.","journal-title":"J Clin Endocrinol Metab"},{"issue":"105","key":"ref_7","first-page":"686","article-title":"Hemochromatosis and hemosiderosis. Study of 211 autopsied cases","volume":"1960","author":"MacDonald, R.A.; Mallory, G.K.","unstructured":"MacDonald RA, Mallory GK. Hemochromatosis and hemosiderosis. Study of 211 autopsied cases. Arch Intern Med 1960; 105: 686-700.","journal-title":"Arch Intern Med"},{"issue":"30","key":"ref_8","first-page":"800","article-title":"Modifications histopathologues de l'hypophyse dans 6 cas d'hemochromatose","volume":"1969","author":"Peillon, F.; Racadot, J.","unstructured":"Peillon F, Racadot J. Modifications histopathologues de l'hypophyse dans 6 cas d'hemochromatose. Ann Endocrinol (Paris) 1969; 30: 800-7.","journal-title":"Ann Endocrinol (Paris)"},{"key":"ref_9","first-page":"611","article-title":"Long-term results of venesection therapy in idiopathic haemochromatosis","volume":"45","author":"Bomford, A.; Williams, R.","year":"1976","unstructured":"Bomford A, Williams R. Long-term results of venesection therapy in idiopathic haemochromatosis. QJ Med 1976; 45: 611-23.","journal-title":"QJ Med"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/j.1365-2265.1993.tb02143.x","article-title":"Reversibility of hypogonadotrophic hypogonadism associated with genetic haemochromatosis","volume":"38","author":"Cundy, T.; Butler, J.; Bomford, A.; Williams, R.","year":"1993","unstructured":"Cundy T, Butler J, Bomford A, Williams R. Reversibility of hypogonadotrophic hypogonadism associated with genetic haemochromatosis. CGin Endocrinol 1993; 38: 617-20.","journal-title":"CGin Endocrinol"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"629","DOI":"10.7326\/0003-4819-101-5-629","article-title":"Hypogonadism in haemochromatosis: reversal with iron depletion","volume":"101","author":"Kelly, T.M.; Edwards, C.Q.; Meikle, A.W.; Kushner, J.P.","year":"1984","unstructured":"Kelly TM, Edwards CQ, Meikle AW, Kushner JP. Hypogonadism in haemochromatosis: reversal with iron depletion. Ann Intern Med 1984; 101: 629-632.","journal-title":"Ann Intern Med"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1210\/jcem-65-3-585","article-title":"Hypogonadotrophic hypogonadism in hemochromatosis: recovery ofreproductive function after iron depletion","volume":"65","author":"Siemons, L.J.; Mahler, C.","year":"1987","unstructured":"Siemons LJ, Mahler C. Hypogonadotrophic hypogonadism in hemochromatosis: recovery ofreproductive function after iron depletion. J Clin Endocrinol Metab 1987; 65: 585-7.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1056\/NEJM198511143132004","article-title":"Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis","volume":"313","author":"Niederau, C.; Fischer, R.; Sonnenberg, A.; Stremmel, W.; Trampisch, H.J.; Strohmeyer, G.","year":"1985","unstructured":"Niederau C, Fischer R, Sonnenberg A, Stremmel W, Trampisch HJ, Strohmeyer G. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N Engl J Med 1985; 313: 1256-62.","journal-title":"N Engl J Med"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/71\/835\/297\/50218829\/postgradmedj-71-297.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/71\/835\/297\/50218829\/postgradmedj-71-297.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T23:23:03Z","timestamp":1683760983000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/71\/835\/297\/7044020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,5,1]]},"references-count":13,"journal-issue":{"issue":"835","published-online":{"date-parts":[[1995,5,1]]},"published-print":{"date-parts":[[1995,5,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.71.835.297","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1995,5]]},"published":{"date-parts":[[1995,5,1]]}}}