{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:47:32Z","timestamp":1779914852746,"version":"3.53.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"839","license":[{"start":{"date-parts":[[1995,9,1]],"date-time":"1995-09-01T00:00:00Z","timestamp":809913600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1995,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Increased urinary calcium (Ca++) excretion and the presence of negative Ca++ balance is well documented in primary hyperaldosteronism. However, renal calculi as a major manifestation of this disorder has not previously been described. This report describes a patient who presented with renal calculi in association with primary hyperaldosteronism. We believe that primary hyperaldosteronism was a major pathogenetic factor in the formation of renal calculi since the increased urinary excretion of Ca++ and uric acid noted at onset declined following a short-term spironolactone administration and remission from renal calculi has persisted following initial nephrolithotomy and continued spironolactone therapy, which also corrected hypertension and hypokalemia, a hallmark of this disorder.<\/jats:p>","DOI":"10.1136\/pgmj.71.839.561","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:25:21Z","timestamp":1230585921000},"page":"561-562","source":"Crossref","is-referenced-by-count":10,"title":["Renal calculi in primary hyperaldosteronism"],"prefix":"10.1093","volume":"71","author":[{"given":"U M","family":"Kabadi","sequence":"first","affiliation":[{"name":"Medical Service, VA Medical Center, Phoenix, and College of Medicine, University of Arizona , Tucson, Arizona , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1995,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0002-9343(85)90328-6","article-title":"Calcium metabolism and parathyroid function in primary aldosteronism","volume":"78","author":"Resnick, L.M.; Largh, J.H.","year":"1985","unstructured":"Resnick LM, Largh JH. Calcium metabolism and parathyroid function in primary aldosteronism. Am J Med 1985; 78: 385-90.","journal-title":"Am J Med"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1056\/NEJM198107233050401","article-title":"Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism","volume":"305","author":"Gross, M.D.; Grekin, R.J.; Gniadek, T.C.; Villareal, J.","year":"1981","unstructured":"Gross MD, Grekin RJ, Gniadek TC, Villareal J. Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism. N Engl J Med 1981; 305: 181-5.","journal-title":"N Engl J Med"},{"key":"ref_3","first-page":"313","article-title":"Some aspects of the metabolic effect of desoxycorticosterone acetate","volume":"2","author":"Luft, R.; Sjogren, B.","year":"1953","unstructured":"Luft R, Sjogren B. Some aspects of the metabolic effect of desoxycorticosterone acetate. Metabolism 1953; 2: 313-21.","journal-title":"Metabolism"},{"key":"ref_4","first-page":"212","article-title":"The effect of long-term desoxycorticosterone acetate administration on the renal excretion of calcium and magnesium","volume":"71","author":"Massry, S.; Coburn, J.W.; Chapman, L.W.; Kleenman, C.R.","year":"1968","unstructured":"Massry S, Coburn JW, Chapman LW, Kleenman CR. The effect of long-term desoxycorticosterone acetate administration on the renal excretion of calcium and magnesium. J Lab Clin Med 1968; 71: 212-9.","journal-title":"J Lab Clin Med"},{"key":"ref_5","first-page":"365","article-title":"Concentrations of ionic and total calcium in plasma of four models of hypertension","volume":"243","author":"Wright, G.L.; Rankin, G.D.","year":"1982","unstructured":"Wright GL, Rankin GD. Concentrations of ionic and total calcium in plasma of four models of hypertension. Am J Physiol 1982; 243: H365-70.","journal-title":"Am J Physiol"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/71\/839\/561\/50219044\/postgradmedj-71-561.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/71\/839\/561\/50219044\/postgradmedj-71-561.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:56:08Z","timestamp":1683766568000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/71\/839\/561\/7046489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9,1]]},"references-count":5,"journal-issue":{"issue":"839","published-online":{"date-parts":[[1995,9,1]]},"published-print":{"date-parts":[[1995,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.71.839.561","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1995,9]]},"published":{"date-parts":[[1995,9,1]]}}}