{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T03:33:05Z","timestamp":1783567985278,"version":"3.55.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"843","license":[{"start":{"date-parts":[[1996,1,1]],"date-time":"1996-01-01T00:00:00Z","timestamp":820454400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We have administered octreotide, 100 micrograms tid, to a 27-year-old man with Nelson\u2019s syndrome. After seven days of therapy, adrenocorticotropin levels fell to 54% of initial values, and some shrinkage of the tumour was observed. This study indicates that octreotide therapy may have a role in the treatment of Nelson\u2019s syndrome.<\/jats:p>","DOI":"10.1136\/pgmj.72.843.53","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:49:00Z","timestamp":1230587340000},"page":"53-54","source":"Crossref","is-referenced-by-count":20,"title":["The effects of octreotide in a patient with Nelson\u2019s syndrome"],"prefix":"10.1093","volume":"72","author":[{"given":"F","family":"Kelestimur","sequence":"first","affiliation":[{"name":"Department of Internal Medicine (Endocrinology), Erciyes University Medical School , 38039 Kayseri- Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Utas","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (Endocrinology), Erciyes University Medical School , 38039 Kayseri- Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Ozbakir","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (Endocrinology), Erciyes University Medical School , 38039 Kayseri- Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Sel\u00e7uklu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Erciyes University Medical School , 38039 Kayseri- Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Kandemir","sequence":"additional","affiliation":[{"name":"Department of Pathology, Erciyes University Medical School , 38039 Kayseri- Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Erciyes University Medical School , 38039 Kayseri- Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1996,1,1]]},"reference":[{"key":"ref_1","first-page":"221","article-title":"The anterior pituitary","volume-title":"textbook ofendocrinology","author":"Thorner, M.O.; Vance, M.L.; Horvath, E.; Kovacs, K.","year":"1992","unstructured":"Thorner MO, Vance ML, Horvath E, Kovacs K. The anterior pituitary. In: Wilson JD, Foster DW, eds. Williams textbook ofendocrinology, Philadelphia: WB Saunders, 1992; pp 221-310."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1210\/jcem-53-5-1084","article-title":"A met-enkephalin analog inhibits adrenocorticotropin secretion by cultured pituitary cells from a patient with Nelson's syndrome","volume":"53","author":"Lamberts, S.W.J.; Oosterom, R.; Verleun, T.; Bons, E.G.; Uitterlinden, P.","year":"1981","unstructured":"Lamberts SWJ, Oosterom R, Verleun T, Bons EG, Uitterlinden P. A met-enkephalin analog inhibits adrenocorticotropin secretion by cultured pituitary cells from a patient with Nelson's syndrome. J Clin Endocrinol Metab 1981; 53: 1084-6.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1210\/jcem-55-5-872","article-title":"Effects of various neuropeptides on the secretion of propiomelanocortin-derived peptides by a cultured pituitary adenoma causing Nelson's syndrome","volume":"55","author":"Shibasaki, T.; Masui, H.","year":"1982","unstructured":"Shibasaki T, Masui H. Effects of various neuropeptides on the secretion of propiomelanocortin-derived peptides by a cultured pituitary adenoma causing Nelson's syndrome.J Clin Endocrinol Metab 1982; 55: 872-6.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1210\/jcem-40-6-1125","article-title":"Inhibition by somatostatin of ACTH secretion in Nelson's syndrome","volume":"40","author":"Thyrrell, J.B.; Lorenzi, M.; Gerich, J.E.; Forsham, P.H.","year":"1975","unstructured":"Thyrrell JB, Lorenzi M, Gerich JE, Forsham PH. Inhibition by somatostatin of ACTH secretion in Nelson's syndrome. J Clin Endocrinol Metab 1975; 40: 1125-7.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1530\/acta.0.1280099","volume":"128","author":"Kelestimur, F.","year":"1993","unstructured":"Kelestimur F. (Letter) Acta Endocrinol 1993; 128: 99.","journal-title":"(Letter) Acta Endocrinol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1136\/pgmj.69.818.920","article-title":"Control of plasma glucose with somatostatin analogue (SMS 201-995) during surgical removal of insulinomas","volume":"69","author":"Utas, C.; Kelestimur, F.; Boyaci, A.; Saglam, A.","year":"1993","unstructured":"Utas C, Kelestimur F, Boyaci A, Saglam A. Control of plasma glucose with somatostatin analogue (SMS 201-995) during surgical removal of insulinomas. Postgrad Med J 1993; 69: 920-1.","journal-title":"Postgrad Med J"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0889-8553(21)00447-7","article-title":"The use of the long-acting somatostatin analogue, octreotide acetate in patients with islet cell tumors","volume":"18","author":"Maten, P.N.","year":"1989","unstructured":"Maten PN. The use of the long-acting somatostatin analogue, octreotide acetate in patients with islet cell tumors. Gastroenterol Clin N Am 1989; 18: 897-922.","journal-title":"Gastroenterol Clin N Am"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1530\/acta.0.1200760","article-title":"The effect of the long-acting somatostatin analogue SMS 201-995 on ACTH secretion in Nelson's syndrome and Cushing's disease","volume":"120","author":"Lamberts, S.W.J.; Uitterlinden, P.; Klijn, J.M.","year":"1989","unstructured":"Lamberts SWJ, Uitterlinden P, Klijn JM. The effect of the long-acting somatostatin analogue SMS 201-995 on ACTH secretion in Nelson's syndrome and Cushing's disease. Acta Endocrinol 1989; 120: 760-6.","journal-title":"Acta Endocrinol"},{"key":"ref_9","first-page":"285","article-title":"Somatostatin receptor imaging in the diagnosis of pituitary and parasellar tumours","volume-title":"clinical advances in pituitary disorders","author":"Lamberts, S.W.J.; Krenning, E.P.; Bakker, W.H.; Breeman, W.A.P.; Kooij, P.P.M.; Reubi, J.C.","year":"1990","unstructured":"Lamberts SWJ, Krenning EP, Bakker WH, Breeman WAP, Kooij PPM, Reubi JC. Somatostatin receptor imaging in the diagnosis of pituitary and parasellar tumours. In: Melmed S, Robbins RJ, eds. Molecular and clinical advances in pituitary disorders. Boston: Blackwell Scientific Publications, 1990; pp 285-92."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1159\/000125200","article-title":"Studies on the conditions determining the inhibitory effect of somatostatin on adrenocorticotropin, prolactin and thyrotropin release by cultured rat pituitary cells","volume":"50","author":"Lamberts, S.W.J.; Zuyderwijk, J.; den Holder, F.; Van Koetsveld, P.; Hofland, L.","year":"1989","unstructured":"Lamberts SWJ, Zuyderwijk J, den Holder F, Van Koetsveld P, Hofland L. Studies on the conditions determining the inhibitory effect of somatostatin on adrenocorticotropin, prolactin and thyrotropin release by cultured rat pituitary cells. Neuroendocrinology 1989; 50: 44-50.","journal-title":"Neuroendocrinology"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/72\/843\/53\/50388432\/postgradmedj-72-53.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/72\/843\/53\/50388432\/postgradmedj-72-53.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T23:43:22Z","timestamp":1684453402000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/72\/843\/53\/7046553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1,1]]},"references-count":10,"journal-issue":{"issue":"843","published-online":{"date-parts":[[1996,1,1]]},"published-print":{"date-parts":[[1996,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.72.843.53","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1996,1]]},"published":{"date-parts":[[1996,1,1]]}}}