{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:48:27Z","timestamp":1761518907909},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"847","license":[{"start":{"date-parts":[[1996,5,1]],"date-time":"1996-05-01T00:00:00Z","timestamp":830908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,5,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>The advent of sophisticated and sensitive radiologic techniques has undoubtedly improved the evaluation of patients with established endocrine disease. An inevitable consequence of the increased sensitivity and widespread availability of modern imaging is, however, the discovery of apparently asymptomatic mass lesions in endocrine tissues. The clinician is then required to determine the appropriate degree of often uncomfortable and costly investigation in a patient with no overt disease. This article attempts to provide guidelines for the management of the \u2018pituitary incidentaloma\u2019, a pituitary mass lesion evident on a computed tomography or magnetic resonance imaging scan performed for a reason other than the evaluation of the pituitary gland.<\/jats:p>","DOI":"10.1136\/pgmj.72.847.258","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:49:00Z","timestamp":1230587340000},"page":"258-262","source":"Crossref","is-referenced-by-count":24,"title":["The evaluation and management of subclinical pituitary disease"],"prefix":"10.1093","volume":"72","author":[{"given":"S G","family":"Soule","sequence":"first","affiliation":[{"name":"Endocrine Unit, Department of Medicine, University College London Medical School, The Middlesex Hospital , London WIN 8AA , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H S","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Endocrine Unit, Department of Medicine, University College London Medical School, The Middlesex Hospital , London WIN 8AA , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1996,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"925","DOI":"10.7326\/0003-4819-112-12-925","article-title":"The pituitary 'incidentaloma'","volume":"112","author":"Molitch, M.E.; Russell, E.J.","year":"1990","unstructured":"Molitch ME, Russell EJ. The pituitary 'incidentaloma'. Ann Intern Med 1990; 112: 925-31.","journal-title":"Ann Intern Med"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"817","DOI":"10.7326\/0003-4819-120-10-199405150-00001","article-title":"Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population","volume":"120","author":"Hall, W.A.; Luciano, M.G.; Doppman, J.L.; Patronas, N.J.; Oldfield, E.H.","year":"1994","unstructured":"Hall WA, Luciano MG, Doppman JL, Patronas NJ, Oldfield EH. Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population. Ann Intern Med 1994; 120: 817-20.","journal-title":"Ann Intern Med"},{"key":"ref_3","first-page":"3","article-title":"Evaluation and treatment of the patient with a pituitary incidentaloma","volume":"80","author":"Molitch, M.E.","year":"1995","unstructured":"Molitch ME. Evaluation and treatment of the patient with a pituitary incidentaloma. J Clin Endocrinol Metab 1995; 80: 3-6.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0889-8529(18)30466-3","article-title":"Differential diagnosis of pituitary tumours","volume":"16","author":"Post, K.D.; McCormick, P.C.; Bello, J.A.","year":"1987","unstructured":"Post KD, McCormick PC, Bello JA. Differential diagnosis of pituitary tumours. Endocrinol Metab Clin North Am 1987; 16: 609-45.","journal-title":"Endocrinol Metab Clin North Am"},{"key":"ref_5","first-page":"1089","article-title":"Clinically nonfunctioning pituitary adenomas","volume":"76","author":"Katznelson, L.; Alexander, J.A.; Kibanski, A.","year":"1993","unstructured":"Katznelson L, Alexander JA, Kibanski A. Clinically nonfunctioning pituitary adenomas. 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Clin Endocrinol 1992; 36: 133-4.","journal-title":"Clin Endocrinol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/0002-9343(52)90027-2","article-title":"The natural history ofCushing's syndrome","volume":"13","author":"Plotz, C.M.; Knowlton, A.I.; Ragan, C.","year":"1952","unstructured":"Plotz CM, Knowlton AI, Ragan C. The natural history ofCushing's syndrome. AmJ Med 1952; 13: 597-614.","journal-title":"AmJ Med"},{"key":"ref_9","first-page":"293","article-title":"An audit of outcome in acromegaly","volume":"86","author":"Bates, A.S.; Van't Hoff, W.; Jones, J.M.; Clayton, R.M.","year":"1993","unstructured":"Bates AS, Van't Hoff W, Jones JM, Clayton RM. An audit of outcome in acromegaly. QJ Med 1993; 86: 293-9.","journal-title":"QJ Med"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1471-0528.1995.tb09090.x","article-title":"Prolactinomas: present day management","volume":"102","author":"Soule, S.G.; Jacobs, H.S.","year":"1995","unstructured":"Soule SG, Jacobs HS. Prolactinomas: present day management. Br J Obstet Gynaecol 1995; 102: 178-81.","journal-title":"Br J Obstet Gynaecol"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1210\/jcem-62-6-1173","article-title":"Reversible hypopituitarism in patients with large nonfunctioning pituitary adenomas","volume":"62","author":"Arafah, B.M.","year":"1986","unstructured":"Arafah BM. Reversible hypopituitarism in patients with large nonfunctioning pituitary adenomas. 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Arch Intern Med 1995; 155: 181-3.","journal-title":"Arch Intern Med"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1210\/jcem-64-5-1021","article-title":"Forearm and vertebral bone mineral in treated and untreated hyperprolactinaemic amenorrhoea","volume":"64","author":"Schlechte, J.; El-Khoury, G.; Kathol, M.; Walkner, L.","year":"1987","unstructured":"Schlechte J, El-Khoury G, Kathol M, Walkner L. Forearm and vertebral bone mineral in treated and untreated hyperprolactinaemic amenorrhoea. J Clin Endocrinol Metab 1987; 64: 1021-6.","journal-title":"J Clin Endocrinol Metab"},{"key":"ref_15","first-page":"698","article-title":"A longitudinal analysis ofpremenopausal bone loss in healthy women and women with hyperprolactinaemia","volume":"75","author":"Schlechte, J.; Walkner, L.; Kathol, M.","year":"1992","unstructured":"Schlechte J, Walkner L, Kathol M. A longitudinal analysis ofpremenopausal bone loss in healthy women and women with hyperprolactinaemia. 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Eur J Endocrinol 1994; 130: 43-52.","journal-title":"Eur J Endocrinol"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/72\/847\/258\/50220033\/postgradmedj-72-258.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/72\/847\/258\/50220033\/postgradmedj-72-258.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T04:47:42Z","timestamp":1683780462000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/72\/847\/258\/7155010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,5,1]]},"references-count":29,"journal-issue":{"issue":"847","published-online":{"date-parts":[[1996,5,1]]},"published-print":{"date-parts":[[1996,5,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.72.847.258","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1996,5]]},"published":{"date-parts":[[1996,5,1]]}}}