{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:36:23Z","timestamp":1757705783402},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"851","license":[{"start":{"date-parts":[[1996,9,1]],"date-time":"1996-09-01T00:00:00Z","timestamp":841536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,9,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We report two AIDS patients who developed acute renal failure while receiving sulphadiazine for cerebral toxoplasmosis. Renal ultrasound revealed diffuse bilateral echogenic shadowing material. \u2018Sheaves of wheat\u2019 crystals, typical of sulphadiazine crystalluria, were present in the urine. One patient required a percutaneous nephrostomy. Hydration and urine alkalinisation resulted in rapid improvement of renal function and ultrasonographic findings. Sulphadiazine-induced crystalluria and acute renal failure is increasingly frequent. Awareness of its existence may lead to prevention and early conservative treatment.<\/jats:p>","DOI":"10.1136\/pgmj.72.851.557","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:49:00Z","timestamp":1230587340000},"page":"557-558","source":"Crossref","is-referenced-by-count":15,"title":["Acute renal failure due to sulphadiazine crystalluria in AIDS patients"],"prefix":"10.1093","volume":"72","author":[{"given":"P","family":"de Sequera","sequence":"first","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Albalate","sequence":"additional","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Vazquez","sequence":"additional","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Abad","sequence":"additional","affiliation":[{"name":"Radiology Department , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Ramiro","sequence":"additional","affiliation":[{"name":"Radiology Department , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Fern\u00e1ndez Guerrero","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Caramelo","sequence":"additional","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Casado","sequence":"additional","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Nephrology Service, Fundacion Jimenez Diaz , Madrid , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1996,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1001\/archinte.1990.00390220113023","article-title":"Sulfadiazine crystalluria revisited","volume":"150","author":"Simon, D.L.; Brosius, B.C.; Rothstein, D.M.","year":"1990","unstructured":"Simon DL, Brosius BC, Rothstein DM. Sulfadiazine crystalluria revisited. Arch Intern Med 1990; 150: 2379-84.","journal-title":"Arch Intern Med"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0022-5347(17)61764-6","article-title":"Sulfonamide crystalluria: a forgotten disease","volume":"104","author":"Dorfman, L.; Smith, J.","year":"1970","unstructured":"Dorfman L, Smith J. Sulfonamide crystalluria: a forgotten disease. J Urol 1970; 104: 482 - 3.","journal-title":"J Urol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0022-5347(17)69857-4","article-title":"Renal complications of sulfonamide therapy","volume":"56","author":"Abeshouse, B.S.; Tankin, L.H.","year":"1946","unstructured":"Abeshouse BS, Tankin LH. Renal complications of sulfonamide therapy. J Urol 1946; 56: 658-87.","journal-title":"J Urol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1001\/jama.1941.02820240001001","article-title":"Therapeutic evaluation and toxic effects on four hundred and forty-six patients","volume":"116","author":"Finland, M.; Strauss, E.; Sulfadiazine, Peterson E.L.","year":"1941","unstructured":"Finland M, Strauss E, Peterson EL. Sulfadiazine. Therapeutic evaluation and toxic effects on four hundred and forty-six patients. JAMA 1941; 116: 2641 - 7.","journal-title":"JAMA"},{"key":"ref_5","first-page":"1183","article-title":"Sulfadiazine-induced obstructive renal failure in a patient with acquired immunodeficiency syndrome (AIDS)","volume":"8","author":"Rivera, M.; Liafio, F.; Fortun, J.; Femrndez-Lucas, M.; Ortuino, J.","year":"1993","unstructured":"Rivera M, Liafio F, Fortun J, Femrndez-Lucas M, Ortuino J. Sulfadiazine-induced obstructive renal failure in a patient with acquired immunodeficiency syndrome (AIDS). Nephrol Dial Transplant 1993; 8: 1183-4.","journal-title":"Nephrol Dial Transplant"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/0002-9343(88)90124-6","article-title":"Sulfadiazine-induced crystalluria in a patient with the acquired immunodeficiency syndrome: a reminder","volume":"84","author":"Sahai, J.; Heimberger, T.; Collins, K.; Kaplowitz, L.; Polk, R.","year":"1988","unstructured":"Sahai J, Heimberger T, Collins K, Kaplowitz L, Polk R. Sulfadiazine-induced crystalluria in a patient with the acquired immunodeficiency syndrome: a reminder. Am J Med 1988; 84: 791-2.","journal-title":"Am J Med"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1148\/radiology.185.3.1438755","article-title":"Renal US findings in sulfadiazine-induced crystalluria","volume":"185","author":"Sasson, J.P.; Dratch, P.L.; Shortsleeve, M.J.","year":"1992","unstructured":"Sasson JP, Dratch PL, Shortsleeve MJ. Renal US findings in sulfadiazine-induced crystalluria. Radiology 1992; 185: 739-40.","journal-title":"Radiology"},{"key":"ref_8","first-page":"180","article-title":"Acute renal failure and sulphadiazine crystalluria in kidney transplant","volume":"9","author":"Portoles, J.; Torralbo, A.; Prats, D.; Blanco, J.; Barrientos, A.","year":"1994","unstructured":"Portoles J, Torralbo A, Prats D, Blanco J, Barrientos A. Acute renal failure and sulphadiazine crystalluria in kidney transplant. Nephrol Dial Transplant 1994; 9: 180-1.","journal-title":"Nephrol Dial Transplant"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/72\/851\/557\/50220061\/postgradmedj-72-557.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/72\/851\/557\/50220061\/postgradmedj-72-557.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T05:13:51Z","timestamp":1683782031000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/72\/851\/557\/7043904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,9,1]]},"references-count":8,"journal-issue":{"issue":"851","published-online":{"date-parts":[[1996,9,1]]},"published-print":{"date-parts":[[1996,9,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.72.851.557","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1996,9]]},"published":{"date-parts":[[1996,9,1]]}}}