{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:01:23Z","timestamp":1761058883983},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"856","license":[{"start":{"date-parts":[[1997,2,1]],"date-time":"1997-02-01T00:00:00Z","timestamp":854755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1997,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 56-year-old man who received a live-related renal transplant in 1988 was started in 1995 on the selective angiotensin II antagonist losartan (Dupont-Merke) to treat worsening hypertension. Two months later because of pulmonary oedema, loop diuretics were started. Within two weeks, serum creatinine had increased from 245 to 571 mumol\/l, and the patient became oliguric. A systolic bruit was noted over the graft. Renal angiography showed a 90% stenosis of the transplant renal artery. Losartan was withdrawn, with prompt improvement in renal function. A successful percutaneous transluminal angioplasty performed a few days later resulted in further improvement in renal function accompanied by a significant diuresis.<\/jats:p>","DOI":"10.1136\/pgmj.73.856.105","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:49:00Z","timestamp":1230587340000},"page":"105-107","source":"Crossref","is-referenced-by-count":17,"title":["Reversible acute renal failure induced by losartan in a renal transplant recipient"],"prefix":"10.1093","volume":"73","author":[{"given":"M","family":"Ostermann","sequence":"first","affiliation":[{"name":"Trafford Department of Renal Medicine, Royal Sussex County Hospital , Brighton, BN2 5BE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D J A","family":"Goldsmith","sequence":"additional","affiliation":[{"name":"Trafford Department of Renal Medicine, Royal Sussex County Hospital , Brighton, BN2 5BE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Doyle","sequence":"additional","affiliation":[{"name":"Department of Radiology, Royal Sussex County Hospital , Brighton, BN2 5BE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J C","family":"Kingswood","sequence":"additional","affiliation":[{"name":"Trafford Department of Renal Medicine, Royal Sussex County Hospital , Brighton, BN2 5BE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Sharpstone","sequence":"additional","affiliation":[{"name":"Trafford Department of Renal Medicine, Royal Sussex County Hospital , Brighton, BN2 5BE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1997,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0140-6736(95)92411-6","article-title":"Angiotensin receptor antagonists: focus on Losartan","volume":"346","author":"Johnston, C.I.","year":"1995","unstructured":"Johnston CI. Angiotensin receptor antagonists: focus on Losartan. Lancet 1995; 346: 1403-7.","journal-title":"Lancet"},{"key":"ref_2","first-page":"1635","article-title":"Renal failure in diabetic neuropathy","volume-title":"textbook of clinical nephrology","author":"Ritz, E.; Koch, M.","year":"1992","unstructured":"Ritz E, Koch M. Renal failure in diabetic neuropathy. In: Cameron S, Davison AM, Grunfeld J-P, Kerr D, Ritz E, eds. Oxford textbook of clinical nephrology. Oxford: Oxford University Press, 1992; pp 1635-55."},{"key":"ref_3","first-page":"2096","article-title":"Renovascular hypertension","volume-title":"textbook of clinical nephrology","author":"Mann, J.; Allenberg, J.-R.; Reisch, C.","year":"1992","unstructured":"Mann J, Allenberg J-R, Reisch C, et al. Renovascular hypertension. In: Cameron S, Davison AM, Grunfeld J-P, Kerr D, Ritz E, eds. Oxford textbook of clinical nephrology. Oxford: Oxford University Press, 1992; pp 2096-117."},{"key":"ref_4","first-page":"1077","article-title":"Ischaemic renal disease","volume-title":"textbook of clinical nephrology","author":"Breyer, J.A.; Jacobson, H.R.","year":"1992","unstructured":"Breyer JA, Jacobson HR. Ischaemic renal disease. In: Cameron S, Davison AM, Grunfeld J-P, Kerr D, Ritz E, eds. Oxford textbook of clinical nephrology. Oxford: Oxford University Press, 1992; pp 1077 - 84."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1056\/NEJM199605093341915","article-title":"Losartan-induced azotemia in a diabetic recipient of a kidney transplant","volume":"354","author":"Cohen, L.S.; Friedman, E.A.","year":"1996","unstructured":"Cohen LS, Friedman EA. Losartan-induced azotemia in a diabetic recipient of a kidney transplant. N EnglJMed 1996; 354: 1271.","journal-title":"N EnglJMed"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/73\/856\/105\/50221149\/postgradmedj-73-105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/73\/856\/105\/50221149\/postgradmedj-73-105.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T05:53:47Z","timestamp":1683784427000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/73\/856\/105\/7042084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,2,1]]},"references-count":5,"journal-issue":{"issue":"856","published-online":{"date-parts":[[1997,2,1]]},"published-print":{"date-parts":[[1997,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.73.856.105","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1997,2]]},"published":{"date-parts":[[1997,2,1]]}}}