{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:23:42Z","timestamp":1767374622198},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"867","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,1,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A 45-year-old man, with a 10-year history of manic depression treated with lithium, was admitted with hyperosmolar, nonketotic coma. He gave a five-year history of polyuria and polydipsia, during which time urinalysis had been negative for glucose. After recovery from hyperglycaemia, he remained polyuric despite normal blood glucose concentrations; water deprivation testing indicated nephrogenic diabetes insipidus, likely to be lithium-induced. We hypothesize that when this man developed type 2 diabetes, chronic polyuria due to nephrogenic diabetes insipidus was sufficient to precipitate hyperosmolar dehydration.<\/jats:p>","DOI":"10.1136\/pgmj.74.867.39","type":"journal-article","created":{"date-parts":[[2008,12,29]],"date-time":"2008-12-29T21:49:00Z","timestamp":1230587340000},"page":"39-41","source":"Crossref","is-referenced-by-count":17,"title":["Hyperosmolar nonketotic coma precipitated by lithium-induced nephrogenic diabetes insipidus"],"prefix":"10.1093","volume":"74","author":[{"given":"H","family":"Azam","sequence":"first","affiliation":[{"name":"Department of Diabetes, Ninewelis Hospital and Medical School , Dundee, Scotland DD1 9SY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R W","family":"Newton","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Ninewelis Hospital and Medical School , Dundee, Scotland DD1 9SY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A D","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Ninewelis Hospital and Medical School , Dundee, Scotland DD1 9SY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C J","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Ninewelis Hospital and Medical School , Dundee, Scotland DD1 9SY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1998,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/0002-9343(84)90539-4","article-title":"NG: Hyperosmolar hyperglycaemic nonketotic syndrome","volume":"77","author":"Khardori, R.; Soler","year":"1984","unstructured":"Khardori R, Soler NG: Hyperosmolar hyperglycaemic nonketotic syndrome. Am Med 1984;77:899-904.","journal-title":"Am Med"},{"key":"ref_2","first-page":"1151","article-title":"Diabetic ketoacidosis and hyperglycaemic non-ketotic coma","volume-title":"International textbook of diabetes mellitus","author":"Marshall, S.M.; Walker, M.; Alberti, K.G.M.M.","year":"1992","unstructured":"Marshall SM, Walker M, Alberti KGMM. Diabetic ketoacidosis and hyperglycaemic non-ketotic coma. In: Alberti KGMM, De Fronzo RA, Keen H. Zimmet P, eds, International textbook of diabetes mellitus, 1st edn. Chichester: J Wiley & Sons, 1992, pp 1151-64.","edition":"1st edn"},{"key":"ref_3","first-page":"427","article-title":"Clinical management of lithium-induced polyuria","volume":"44","author":"Martin, A.","year":"1993","unstructured":"Martin A. Clinical management of lithium-induced polyuria. Hosp Commun Psychiatry 1993;44:427-8.","journal-title":"Hosp Commun Psychiatry"},{"issue":"3","key":"ref_4","first-page":"14","article-title":"Abnormal osmoregulation in survivors of hyperosmolar coma","volume":"13","author":"Thompson, C.J.; Morris, A.; Baylis, P.H.; Newton, R.W.","year":"1996","unstructured":"Thompson CJ, Morris A, Baylis PH, Newton RW. Abnormal osmoregulation in survivors of hyperosmolar coma. Diabet Med 1996;13(suppl 3):S14.","journal-title":"Diabet Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(95)92783-2","article-title":"Hyperosmolar coma due to lithium-induced diabetes insipidus","volume":"346","author":"McGregor, D.A.; Baker, A.M.; Appel, R.G.; Ober, K.P.; Zaloga, G.P.","year":"1995","unstructured":"McGregor DA, Baker AM, Appel RG, Ober KP, Zaloga GP. Hyperosmolar coma due to lithium-induced diabetes insipidus. Lancet 1995;346:413-7.","journal-title":"Lancet"},{"issue":"1","key":"ref_6","first-page":"527","article-title":"Reversal of renal resistance to vasopressin after improvement in glycaemic control in Type 1 diabetes (abstract)","volume":"11","author":"Thompson, C.J.; Frier, B.M.","year":"1994","unstructured":"Thompson CJ, Frier BM. Reversal of renal resistance to vasopressin after improvement in glycaemic control in Type 1 diabetes (abstract). Diabet Med 1994;11(suppl 1):527.","journal-title":"Diabet Med"},{"key":"ref_7","first-page":"473","article-title":"Polyuric states in man. CGin Endocrinol Metab","volume":"3","author":"Thompson, C.J.","year":"1989","unstructured":"Thompson CJ. Polyuric states in man. CGin Endocrinol Metab 1989;3:473-97."},{"key":"ref_8","first-page":"333","article-title":"Vasopressin secretion in the DIDMOAD (Wolfram) syndrome","volume":"264","author":"Thompson, C.J.; Charlton, J.; Walford, S.","year":"1989","unstructured":"Thompson CJ, Charlton J, Walford S, et al. Vasopressin secretion in the DIDMOAD (Wolfram) syndrome. QJMed 1989;264:333-45.","journal-title":"QJMed"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"113","DOI":"10.7326\/0003-4819-112-2-113","article-title":"Fatal central diabetes mellitus and insipidus resulting from untreated hyponatraemia: a new syndrome","volume":"12","author":"Fraser, C.L.; Arieff, A.I.","year":"1990","unstructured":"Fraser CL, Arieff AI. Fatal central diabetes mellitus and insipidus resulting from untreated hyponatraemia: a new syndrome. Ann Intern Med 1990; 12: 113-9.","journal-title":"Ann Intern Med"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/74\/867\/39\/50221816\/postgradmedj-74-39.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/74\/867\/39\/50221816\/postgradmedj-74-39.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T06:00:35Z","timestamp":1683871235000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/74\/867\/39\/7061082"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1,1]]},"references-count":9,"journal-issue":{"issue":"867","published-online":{"date-parts":[[1998,1,1]]},"published-print":{"date-parts":[[1998,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.74.867.39","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1998,1]]},"published":{"date-parts":[[1998,1,1]]}}}