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Post-operatively, she developed metastatic disease resistant to conventional chemotherapy. Octreotide, a somatostatin analogue which is effective in the treatment of several types of neuroendocrine tumour, was tried to ameliorate her secretory symptoms, but without any therapeutic effect.<\/jats:p>","DOI":"10.1136\/pgmj.75.880.96","type":"journal-article","created":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T00:04:10Z","timestamp":1424217850000},"page":"96-98","update-policy":"http:\/\/dx.doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Lack of response to octreotide in Cushing's syndrome due to metastatic adrenocortical carcinoma"],"prefix":"10.1093","volume":"75","author":[{"given":"N N","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Imperial College School of Medicine, Chelsea & Westminster Hospital , 369 Fulham Road, London SW10 9NH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A J","family":"Isaacs","sequence":"additional","affiliation":[{"name":"Department 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