{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:23:22Z","timestamp":1762017802224},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"883","license":[{"start":{"date-parts":[[1999,5,1]],"date-time":"1999-05-01T00:00:00Z","timestamp":925516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1999,5,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>We report two patients with type 1 diabetes mellitus, previously well controlled with good compliance, presenting with unexplained diabetic ketoacidosis. Following initial correction of the metabolic disorder, persisting tachycardia lead to the diagnosis of thyrotoxicosis. In both cases, treatment with propranolol and carbimazole helped in the stabilization of their metabolic states. Although thyrotoxicosis is known to destabilise diabetes control, we can find no reports of it precipitating diabetic ketoacidosis.<\/jats:p>","DOI":"10.1136\/pgmj.75.883.291","type":"journal-article","created":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T00:04:10Z","timestamp":1424217850000},"page":"291-292","update-policy":"http:\/\/dx.doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Diabetic ketoacidosis precipitated by thyrotoxicosis"],"prefix":"10.1093","volume":"75","author":[{"given":"A","family":"Bhattacharyya","sequence":"first","affiliation":[{"name":"Diabetes Centre, North Manchester General Hospital , Crumpsall, Manchester M8 5RB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P G","family":"Wiles","sequence":"additional","affiliation":[{"name":"Diabetes Centre, North Manchester General Hospital , Crumpsall, Manchester M8 5RB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1999,5,1]]},"reference":[{"key":"2023042616333451800_B1","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1001\/archinte.1975.00330110067009","article-title":"Long term observation of glucose tolerance in thyrotoxic patients","volume":"135","author":"Maxon","year":"1975","journal-title":"Arch Intern Med"},{"key":"2023042616333451800_B2","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1210\/jcem-60-6-1063","article-title":"Glucose metabolism in non-insulin dependent diabetic patients with experimental hyperthyroidism","volume":"60","author":"Bratusch-Marrain","year":"1985","journal-title":"J Clin Endocrinol Metab"},{"key":"2023042616333451800_B3","first-page":"722","article-title":"Increased insulin responsiveness and clearance in thyrotoxicosis","volume":"21","author":"Barzilai","year":"1985","journal-title":"Isr J Med"},{"key":"2023042616333451800_B4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.2337\/diacare.12.5.319","article-title":"Increased insulin action and clearance in hyperthyroid newly diagnosed IDDM patient. Restoration to normal with antithyroid treatment","volume":"12","author":"Nijs","year":"1989","journal-title":"Diabetes Care"},{"key":"2023042616333451800_B5","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/0005-2760(83)90025-5","article-title":"The outer carritine palmitoyl transferase and regulation of fatty acid metabolism in rat liver in different thyroid states","volume":"750","author":"Stakkestad","year":"1983","journal-title":"Biochim Biophys Acta"},{"key":"2023042616333451800_B6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3181\/00379727-203-43572","article-title":"Uptake of ketone bodies in perfused hind quarter and kidney of starved, thyrotoxic and diabetic rats","volume":"203","author":"Ikeda","year":"1993","journal-title":"Proc Soc Exp Biol Med"},{"key":"2023042616333451800_B7","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/archinte.1980.00330150122028","article-title":"Thyrotoxicosis without elevated serum triiodothyroxine levels during diabetic ketoacidosis","volume":"140","author":"Rolald","year":"1980","journal-title":"Arch Intern Med"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article\/75\/883\/291\/7044810","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article\/75\/883\/291\/7044810","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T16:34:52Z","timestamp":1682526892000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/75\/883\/291\/7044810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,5,1]]},"references-count":7,"journal-issue":{"issue":"883","published-online":{"date-parts":[[1999,5,1]]},"published-print":{"date-parts":[[1999,5,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pgmj.75.883.291","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1999,5]]},"published":{"date-parts":[[1999,5,1]]}}}