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Patients will have to be changed to the devices in a co-ordinated manner to avoid any risk to their health and safety. The different shapes and aerosol delivery characteristics of the new inhalers, as well as their distinctive taste, could add to the levels of poor drug use already experienced in asthma. From previous change scenarios in disease management, the potential for unstable asthma control is a real possibility with all the attendant costs. By using the time available before CFC-based inhalers are withdrawn, there is an opportunity to enhance asthma management during this period of change.<\/jats:p>","DOI":"10.1136\/pgmj.75.890.710","type":"journal-article","created":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T00:04:10Z","timestamp":1424217850000},"page":"710-714","update-policy":"http:\/\/dx.doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Challenges in changing to non-chlorofluorocarbon inhalers in the treatment of asthma"],"prefix":"10.1093","volume":"75","author":[{"given":"T","family":"Walley","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Therapeutics, University of Liverpool , Liverpool L69 3GF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Bundred","sequence":"additional","affiliation":[{"name":"Department of Primary Care, University of Liverpool , Liverpool L69 3GF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Rannard","sequence":"additional","affiliation":[{"name":"Department of Primary Care, University of Liverpool , Liverpool L69 3GF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Bogg","sequence":"additional","affiliation":[{"name":"Department of Primary Care, University of Liverpool , Liverpool L69 3GF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1999,12,1]]},"reference":[{"key":"2023050812334932500_bib1","first-page":"17","article-title":"Chlorofluorocarbon free inhalers","volume":"9","year":"1998","journal-title":"Med Resource Cent Bull"},{"key":"2023050812334932500_bib2","volume-title":"United Nations Environment Programme Technology and Economic Assessment Panel of the Montreal Protocol on substances that deplete the ozone layer. 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