{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T22:02:23Z","timestamp":1794002543809,"version":"4.8.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1174","license":[{"start":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T00:00:00Z","timestamp":1662681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100007217","name":"Health Services Research and Development","doi-asserted-by":"publisher","award":["5I01BX004511-04"],"award-info":[{"award-number":["5I01BX004511-04"]}],"id":[{"id":"10.13039\/100007217","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thiamine is present in many foods and is well recognised as an essential nutrient critical for energy metabolism. While thiamine deficiency is commonly recognised in alcoholism, it can present in many other settings where it is often not considered and goes unrecognised. One challenging aspect to diagnosis is that it may have varied metabolic, neurological and cardiac presentations. Here we present an overview of the disorder, focusing on the multiple causes and clinical presentations. Interestingly, thiamine deficiency is likely increasing in frequency, especially among wildlife, where it is linked with changing environments and climate change. Thiamine deficiency should be considered whenever neurological or cardiological disease of unknown aetiology presents, especially in any patient presenting with lactic acidosis.<\/jats:p>","DOI":"10.1136\/pmj-2022-141972","type":"journal-article","created":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T17:59:19Z","timestamp":1662746359000},"page":"844-848","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Thiamine deficiency: a commonly unrecognised but easily treatable condition"],"prefix":"10.1093","volume":"99","author":[{"given":"Tritia","family":"Schostak","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine , , Aurora, Colorado , USA"},{"name":"Rocky Mountain Regional VA Medical Center , , Aurora, Colorado , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I\u0148igo","family":"San Millan","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine , , Aurora, Colorado , USA"},{"name":"University of Colorado\u2014Anschutz Medical Campus , , Aurora, Colorado , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alkesh","family":"Jani","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine , , Aurora, Colorado , USA"},{"name":"Rocky Mountain Regional VA Medical Center , , Aurora, Colorado , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3312-8193","authenticated-orcid":false,"given":"Richard Joseph","family":"Johnson","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine , , Aurora, Colorado , USA"},{"name":"Rocky Mountain Regional VA Medical Center , , Aurora, Colorado , USA"},{"name":"Division of Endocrinology, Department of Medicine , , Aurora, Colorado , USA"},{"name":"University of Colorado\u2014Anschutz Medical Campus , , Aurora, Colorado , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,9,9]]},"reference":[{"key":"2023072515564180100_R1","article-title":"Worked to death: how a Chinese tuna juggernaut crushed its Indonesian workers secondary worked to death how a Chinese tuna juggernaut crushed its Indonesian workers","author":"MaTaTER","year":"2021"},{"key":"2023072515564180100_R2","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.809485","article-title":"Chronic lactate exposure decreases mitochondrial function by inhibition of fatty acid uptake and cardiolipin alterations in neonatal rat cardiomyocytes","volume":"9","author":"San-Millan","year":"2022","journal-title":"Front Nutr"},{"key":"2023072515564180100_R3","doi-asserted-by":"crossref","first-page":"12002","DOI":"10.1074\/jbc.REV120.010918","article-title":"The importance of thiamine (vitamin B1) in plant health: From crop yield to 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