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New dimensions were uncovered by biochemistry and immunology, bringing it still nearer the elusive enigma, namely the cause of sarcoidosis. Aetiology includes an understanding of a genetic predisposition and environmental trigger factors. What was left undone in the 20th century will become evident in the 21st century with more sophisticated technology. Likewise, conventional treatments of the past will be superseded by cytokines and other magic bullets of the millennium.<\/jats:p>","DOI":"10.1136\/pmj.77.905.177","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:38:40Z","timestamp":1027766320000},"page":"177-180","source":"Crossref","is-referenced-by-count":25,"title":["Sarcoidosis 2001"],"prefix":"10.1093","volume":"77","author":[{"given":"D Geraint","family":"James","sequence":"first","affiliation":[{"name":"Royal Free Hospital , London NW3 2QG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2001,3,1]]},"reference":[{"key":"2023042418533696800_B1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/096777209500300305","article-title":"The sarcoidosis movement and its personalities.","volume":"3","author":"James","year":"1995","journal-title":"Journal of Medical Biography"},{"key":"2023042418533696800_B2","first-page":"705","article-title":"The distribution of lymphoid-and macrophage-like subsets of sarcoid and Kveim granulomata; 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