{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T03:55:33Z","timestamp":1772855733277,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"905","license":[{"start":{"date-parts":[[2001,3,1]],"date-time":"2001-03-01T00:00:00Z","timestamp":983404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A case of colchicine induced rhabdomyolysis is reported. A 73 year old man with ischaemic heart disease, atrial fibrillation, chronic congestive cardiac failure, and chronic gout presented with diffuse muscle pain. He had been taking an increased dose of colchicine (1.5 mg daily) for an exacerbation of gout for six weeks before the presentation. Investigations confirmed the diagnosis of rhabdomyolysis and discontinuation of colchicine resulted in resolution of clinical and biochemical features of rhabdomyolysis. Although neuromuscular adverse effects of colchicine are well recognised, rhabdomyolysis is rare and this is only the fourth reported case of colchicine induced rhabdomyolysis in the literature.<\/jats:p>","DOI":"10.1136\/pmj.77.905.191","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:38:40Z","timestamp":1027766320000},"page":"191-192","source":"Crossref","is-referenced-by-count":43,"title":["Colchicine induced rhabdomyolysis"],"prefix":"10.1093","volume":"77","author":[{"given":"I","family":"Chattopadhyay","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine, Ysbyty Gwynedd Hospital , Bangor, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H G M","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Integrated Medicine, University Hospital of Wales , Cardiff CF4 4XW, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Routledge","sequence":"additional","affiliation":[{"name":"Therapeutics and Toxicology Group, University Hospital of Wales College of Medicine , Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry, University Hospital of Wales , Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2001,3,1]]},"reference":[{"key":"2023042418535005600_B1","first-page":"647","volume-title":"The pharmacological basis of therapeutics.","author":"Insel","year":"1996","edition":"9th"},{"key":"2023042418535005600_B2","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1056\/NEJM198706183162502","article-title":"Colchicine myopathy and neuropathy.","volume":"316","author":"Kuncl","year":"1987","journal-title":"N Engl J Med"},{"key":"2023042418535005600_B3","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/(SICI)1097-4598(199607)19:7<870::AID-MUS9>3.0.CO;2-6","article-title":"Myotonia in colchicine myoneuropathy.","volume":"19","author":"Rutkove","year":"1996","journal-title":"Muscle Nerve"},{"key":"2023042418535005600_B4","first-page":"1237","article-title":"Toxic myopathy with kidney failure as a colchicine side effect in familial Mediterranean fever.","volume":"117","author":"Stefandis","year":"1992","journal-title":"Dtsch Med Wochenschr"},{"key":"2023042418535005600_B5","first-page":"2045","article-title":"Colchicine induced rhabdomyolysis.","volume":"24","author":"Dawson","year":"1997","journal-title":"J Rheumatol"},{"key":"2023042418535005600_B6","first-page":"109","volume-title":"Side effects of drugs. Annual 5.","author":"Del Favero","year":"1981"},{"key":"2023042418535005600_B7","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3346\/jkms.1997.12.2.160","article-title":"Acute myopathy induced by colchicine in a cyclosporine-treated renal transplant recipient\u2014a case report and review of the literature.","volume":"12","author":"Lee","year":"1997","journal-title":"J Korean Med Sci"},{"key":"2023042418535005600_B8","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0303-8467(97)00092-9","article-title":"Acute onset of colchicine myoneuropathy in cardiac transplant recipients: case studies of three patients.","volume":"99","author":"Rana","year":"1997","journal-title":"Clin Neurol Neurosurg"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/77\/905\/191\/50043819\/postgradmedj-77-191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/77\/905\/191\/50043819\/postgradmedj-77-191.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T18:55:29Z","timestamp":1682362529000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/77\/905\/191\/7039031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3,1]]},"references-count":8,"journal-issue":{"issue":"905","published-online":{"date-parts":[[2001,3,1]]},"published-print":{"date-parts":[[2001,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pmj.77.905.191","relation":{},"ISSN":["1469-0756","0032-5473"],"issn-type":[{"value":"1469-0756","type":"electronic"},{"value":"0032-5473","type":"print"}],"subject":[],"published-other":{"date-parts":[[2001,3]]},"published":{"date-parts":[[2001,3,1]]}}}