{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:07:32Z","timestamp":1788480452850,"version":"build-2803163510"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"917","license":[{"start":{"date-parts":[[2002,3,1]],"date-time":"2002-03-01T00:00:00Z","timestamp":1014940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Coronary ischaemia in acute endocarditis is usually due to pre-existing coronary disease or occasionally as a result of embolism from vegetations. A 68 year old man with known mixed aortic valve disease presented with a four week history of progressive exertional angina, which became unstable. He was apyrexial with no peripheral signs of endocarditis. Three sets of blood cultures were negative. Transthoracic echocardiography with suboptimal windows confirmed moderate mixed aortic valve disease. Marked reversible ST segment depression with angina recurred at rest. Aortography showed severe aortic regurgitation with a distorted aortic root. Coronary angiography showed severe proximal narrowing of the left anterior descending and circumflex arteries with an unusual long and tapering contour. Emergency surgery revealed a large anterior aortic root abscess which had destroyed the left and right coronary cusps. Aortic root abscess and other rare causes of extrinsic coronary compression are discussed.<\/jats:p>","DOI":"10.1136\/pmj.78.917.168","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:29:57Z","timestamp":1027765797000},"page":"168-169","source":"Crossref","is-referenced-by-count":15,"title":["Aortic root abscess presenting as unstable angina due to extrinsic compression of the left coronary artery"],"prefix":"10.1093","volume":"78","author":[{"given":"N R A","family":"Clarke","sequence":"first","affiliation":[{"name":"John Radcliffe Hospital , Headley Way, Oxford OX3 9DU , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Forfar","sequence":"additional","affiliation":[{"name":"John Radcliffe Hospital , Headley Way, Oxford OX3 9DU , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2002,3,1]]},"reference":[{"key":"2023042416152359800_R1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0167-5273(87)90184-7","article-title":"Coronary artery compression caused by abscess formation in infective endocarditis","volume":"14","author":"Cripps","year":"1987","journal-title":"Int J Cardiol"},{"key":"2023042416152359800_R2","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0167-5273(93)90157-C","article-title":"Myocardial infarction due to coronary artery compression by aortic root abscess","volume":"41","author":"Dean","year":"1993","journal-title":"Int J Cardiol"},{"key":"2023042416152359800_R3","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/ccd.1810230212","volume":"23","author":"Wickline","year":"1991","journal-title":"Cathet Cardiovasc Diagn"},{"key":"2023042416152359800_R4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1161\/01.CIR.54.1.140","article-title":"Valve ring abscess in active infective endocarditis. Frequency, location and clues to clinical diagnosis from the study of 95 necropsy patients","volume":"54","author":"Arnett","year":"1976","journal-title":"Circulation"},{"key":"2023042416152359800_R5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1148\/radiology.153.2.6484167","article-title":"Aortic root abscess resulting from endocarditis; spectrum of angiographic findings","volume":"153","author":"Miller","year":"1984","journal-title":"Radiology"},{"key":"2023042416152359800_R6","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1161\/01.CIR.86.2.353","article-title":"Transoesophageal echocardiographic recognition of subaortic complications in aortic valve endocarditis. Clinical and surgical implications","volume":"86","author":"Karalis","year":"1992","journal-title":"Circulation"},{"key":"2023042416152359800_R7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0002-8703(95)90031-4","article-title":"Angina caused by systolic compression of the left coronary artery as a result of pseudoaneurysm of the mitral-aortic intervalvular fibrosa","volume":"129","author":"Parashara","year":"1995","journal-title":"Am Heart J"},{"key":"2023042416152359800_R8","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/0002-8703(87)90944-6","article-title":"False aneurysm of the aortic root: mimic of malignancy, mediator of myocardial ischaemia","volume":"113","author":"Rogers","year":"1987","journal-title":"Am Heart J"},{"key":"2023042416152359800_R9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0022-5223(19)40104-9","article-title":"Aneurysm of the sinus of Valsalva producing obstruction of the left main coronary artery","volume":"72","author":"Gardia-Rinaldi","year":"1976","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2023042416152359800_R10","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/clc.4960130510","article-title":"External compression by metastatic squamous carcinoma: a rare cause of left main coronary artery narrowing","volume":"13","author":"Weinberg","year":"1990","journal-title":"Clin Cardiol"},{"key":"2023042416152359800_R11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1540-8191.1990.tb00737.x","article-title":"Predictors of outcome in patients with prosthetic valve endocarditis (PVE) and potential advantages of homograft aortic root replacement for prosthetic ascending aortic valve-graft infections","volume":"5","author":"Miller","year":"190","journal-title":"J Card Surg"},{"key":"2023042416152359800_R12","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/0003-4975(90)90311-S","article-title":"Results of homograft aortic valve replacement for active endocarditis","volume":"49","author":"Tuna","year":"1990","journal-title":"Ann Thorac Surg"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/78\/917\/168\/50039880\/postgradmedj-78-168.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/78\/917\/168\/50039880\/postgradmedj-78-168.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T16:18:02Z","timestamp":1682353082000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/78\/917\/168\/7038950"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3,1]]},"references-count":12,"journal-issue":{"issue":"917","published-online":{"date-parts":[[2002,3,1]]},"published-print":{"date-parts":[[2002,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pmj.78.917.168","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2002,3]]},"published":{"date-parts":[[2002,3,1]]}}}