{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T05:09:20Z","timestamp":1780117760066,"version":"3.54.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"928","license":[{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thallium poisoning is known for its diverse manifestations and these can delay the diagnosis if a clear history of poisoning is not forthcoming. A 42 year old man presented on the third day of illness with flaccid quadriparesis and paresthesia, which were confused with Guillain-Barr\u00e9 syndrome. Because of associated loose motions, skin lesions, and liver and kidney dysfunction arsenic poisoning was considered. In the second week he developed ophthalmoplegia, nystagmus, and neck tremor and later developed alopecia, and thallium poisoning was suspected. His serum thallium level on the 18th day of illness was 40 980 \u03bcg\/ml. He was subjected to haemodialysis, potassium supplementation, laxatives, and B complex supplementation. He showed significant improvement after haemodialysis and at three months he was able to walk with support. At six months of follow up he was independent for activities of daily living. Severe paresthesia, ophthalmoplegia, cerebellar and extrapyramidal signs, and alopecia are highly suggestive of thallium poisoning. Haemodialysis may be effective even in the third week of poisoning.<\/jats:p>","DOI":"10.1136\/pmj.79.928.103","type":"journal-article","created":{"date-parts":[[2003,3,5]],"date-time":"2003-03-05T16:04:10Z","timestamp":1046880250000},"page":"103-105","source":"Crossref","is-referenced-by-count":53,"title":["Thallium poisoning: emphasis on early diagnosis and response to haemodialysis"],"prefix":"10.1093","volume":"79","author":[{"given":"U K","family":"Misra","sequence":"first","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences , Lucknow , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Kalita","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences , Lucknow , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R K","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences , Lucknow , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Ranjan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences , Lucknow , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2003,2,1]]},"reference":[{"key":"2023042409331749700_R1","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1136\/bmj.306.6891.1527","article-title":"Thallium poisoning. Diagnosis may be elusive but alopecia is the clue","volume":"306","author":"Moore","year":"1993","journal-title":"BMJ"},{"key":"2023042409331749700_R2","first-page":"939","article-title":"Clinical features and therapy of acute thallium poisoning","volume":"69","author":"Wainwroght","year":"1988","journal-title":"Q J Med"},{"key":"2023042409331749700_R3","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/mus.880130510","article-title":"Electrophysiologic investigation of thallium poisoning","volume":"13","author":"Dumitru","year":"1990","journal-title":"Muscle Nerve"},{"key":"2023042409331749700_R4","first-page":"133","article-title":"Thallium poisoning","volume":"17","author":"Bohringer","year":"1980","journal-title":"Toxicology"},{"key":"2023042409331749700_R5","doi-asserted-by":"crossref","first-page":"6738","DOI":"10.1016\/S0021-9258(19)42121-2","article-title":"Thallium-205 nuclear relation and kinetic studies of sodium and potassium ion activated triphosphatase","volume":"294","author":"Grisham","year":"1974","journal-title":"J Biol Chem"},{"key":"2023042409331749700_R6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0009-2797(78)90043-1","article-title":"The toxicity of thallium (I) to cardiac and skeletal muscle","volume":"23","author":"Hughes","year":"1978","journal-title":"Chem Biol Interact"},{"key":"2023042409331749700_R7","first-page":"239","article-title":"Thallium poisoning","volume-title":"Handbook of clinical neurology","author":"Prick","year":"1979"},{"key":"2023042409331749700_R8","first-page":"199","article-title":"Arsenic poisoning","volume-title":"Intoxications of the nervous system","author":"Chhutani","year":"1979"},{"key":"2023042409331749700_R9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-2990.1991.tb00687.x","article-title":"What have we learnt from Frederick Young? Reflections in the mechanism of thallium neurotoxicity","volume":"17","author":"Cavanagh","year":"1991","journal-title":"Neuropathol Appl Neurobiol"},{"key":"2023042409331749700_R10","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.3109\/15563658208992536","article-title":"Acute thallium poisoning: an evaluation of different forms of treatment","volume":"19","author":"Nogue","year":"1982","journal-title":"J Toxicol Clin Toxicol"},{"key":"2023042409331749700_R11","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1081\/CLT-100102462","article-title":"Comparative efficacy of thallium adsorption by activated charcoal Prussian blue and sodium polystyrene sulfonate","volume":"37","author":"Hoffman","year":"1999","journal-title":"J Toxiol Clin Toxicol"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/79\/928\/103\/50038871\/postgradmedj-79-103.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/79\/928\/103\/50038871\/postgradmedj-79-103.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T09:53:38Z","timestamp":1682330018000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/79\/928\/103\/7045527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2,1]]},"references-count":11,"journal-issue":{"issue":"928","published-online":{"date-parts":[[2003,2,1]]},"published-print":{"date-parts":[[2003,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pmj.79.928.103","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2003,2]]},"published":{"date-parts":[[2003,2,1]]}}}