{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:56:30Z","timestamp":1760061390567},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"928","license":[{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This is a case report of a previously healthy woman of 56 years who presented with a life threatening tetraparesis, severe hypokalaemia, hypertension, and raised muscle enzymes. The cause of was finally found to be unusual and very much \u201clocal\u201d. Initial inquiry into her drug history was negative until she was made aware that herbal remedies could cause serious adverse reactions. She then mentioned that she had been eating a large number of \u201cPontefract cakes\u201d (a liquorice sweet) for the management of her chronic constipation. This case highlights the importance of asking about herbal remedies when taking a drug history in all patients, including those admitted as medical emergencies.<\/jats:p>","DOI":"10.1136\/pmj.79.928.115","type":"journal-article","created":{"date-parts":[[2003,3,5]],"date-time":"2003-03-05T16:04:10Z","timestamp":1046880250000},"page":"115-116","source":"Crossref","is-referenced-by-count":12,"title":["The sweet cake that reaches parts other cakes can\u2019t!"],"prefix":"10.1093","volume":"79","author":[{"given":"R M","family":"Hussain","sequence":"first","affiliation":[{"name":"Integrated Department of General Medicine, Pontefract General Infirmary , Friarwood Lane, Pontefract, West Yorkshire WF8 1PL , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2003,2,1]]},"reference":[{"key":"2023042409330628100_R1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1001\/jama.1968.03140330034006","article-title":"Liquorice induced pseudohyperaldosteronism. Hypertension, hypokalemia, aldosternopenia and suppressed plasma rennin activity.","volume":"205","author":"Conn","year":"1968","journal-title":"JAMA"},{"key":"2023042409330628100_R2","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1084\/jem.106.3.415","article-title":"Deoxy corticosterone-mimetic action of ammoniated glycyrrhizin in rats.","volume":"106","author":"Kraus","year":"1957","journal-title":"J Exp Med"},{"key":"2023042409330628100_R3","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0140-6736(87)91014-2","article-title":"Mineralocorticoid activity of liquorice: 11-beta-hydrogenase deficiency comes of age.","volume":"ii","author":"Stewart","year":"1987","journal-title":"Lancet"},{"key":"2023042409330628100_R4","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1056\/NEJM199110243251709","article-title":"Lessons from liquorice.","volume":"24","author":"Edward","year":"1991","journal-title":"N Engl J Med"},{"key":"2023042409330628100_R5","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000013572","article-title":"Low dose of liquorice can induce hypertensive encephalophthy.","volume":"20","author":"Russo","year":"2000","journal-title":"Am J Nephrol"},{"key":"2023042409330628100_R6","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0889-8529(18)30102-6","article-title":"Liquorice induced hypertension and syndrome of apparent mineralocoticoid excess.","volume":"23","author":"Walker","year":"1994","journal-title":"Endocrinol Metab Clin North Am"},{"key":"2023042409330628100_R7","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1046\/j.1365-2796.1999.00476.x","article-title":"Life threatening ventricular tachycardia due to liquorice-induced hypokalaemia.","volume":"245","author":"Eriksson","year":"1999","journal-title":"J Intern Med"},{"key":"2023042409330628100_R8","first-page":"631","article-title":"Upper limb induced by liquorice ingestion.","volume":"41","author":"Lanazo","year":"2000","journal-title":"J Cardiovasc Surg"},{"key":"2023042409330628100_R9","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1056\/NEJM196603172741104","article-title":"Hypokalaemic myopathy with myoglobinuria associated with liquorice ingestion.","volume":"274","author":"Gross","year":"1966","journal-title":"N Engl J Med"},{"key":"2023042409330628100_R10","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/sj.jhh.1001215","article-title":"Liquorice-induced rise in blood pressure linear dose-response relationship.","volume":"15","author":"Sigurionsnsdottir","year":"2001","journal-title":"J Hum Hypertens"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/79\/928\/115\/50038655\/postgradmedj-79-115.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/79\/928\/115\/50038655\/postgradmedj-79-115.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T09:34:18Z","timestamp":1682328858000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/79\/928\/115\/7045597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2,1]]},"references-count":10,"journal-issue":{"issue":"928","published-online":{"date-parts":[[2003,2,1]]},"published-print":{"date-parts":[[2003,2,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pmj.79.928.115","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2003,2]]},"published":{"date-parts":[[2003,2,1]]}}}