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Chest radiography and tuberculin testing with or without tissue for culture are still the standard tools for confirming the diagnosis once this is considered. Well researched treatment protocols are available but multidrug resistant tuberculosis and coexistent HIV are a challenge. Ensuring compliance with treatment is a major concern. Controversy still surrounds the place of BCG. Advances in the molecular genetics of tuberculosis hold out the possibility of better vaccines.<\/jats:p>","DOI":"10.1136\/pmj.79.931.272","type":"journal-article","created":{"date-parts":[[2003,6,4]],"date-time":"2003-06-04T01:35:18Z","timestamp":1054690518000},"page":"272-278","source":"Crossref","is-referenced-by-count":14,"title":["Paediatric tuberculosis"],"prefix":"10.1093","volume":"79","author":[{"given":"W","family":"Hoskyns","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2003,5,1]]},"reference":[{"key":"2023042410194454400_R1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1136\/thorax.56.3.173","article-title":"Tuberculosis at the end of the 20th century in England and Wales: results of a national survey in 1998","volume":"56","author":"Rose","year":"2001","journal-title":"Thorax"},{"key":"2023042410194454400_R2","volume-title":"Tuberculosis in children","author":"Miller","year":"1982"},{"key":"2023042410194454400_R3","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1164\/arrd.1963.87.3P1.354","article-title":"The natural history of tuberculosis in the human body. 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