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The severe derangement of hyponatraemia, hypokalaemia, and alkalosis appears to have been reasonably well tolerated due to the gradual onset and relatively long history. The causes, mechanism, and management of metabolic alkalosis are discussed.<\/jats:p>","DOI":"10.1136\/pmj.79.933.414","type":"journal-article","created":{"date-parts":[[2003,8,1]],"date-time":"2003-08-01T19:53:17Z","timestamp":1059767597000},"page":"414-415","source":"Crossref","is-referenced-by-count":5,"title":["Metabolic alkalosis and myoclonus"],"prefix":"10.1093","volume":"79","author":[{"given":"P","family":"Simons","sequence":"first","affiliation":[{"name":"Influenza Laboratory, ERNVL, Public Health Laboratory Service , London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Nadra","sequence":"additional","affiliation":[{"name":"BHF Cardiovascular Medicine Unit, National Heart and Lung Institute, Imperial College School of Medicine, Hammersmith Hospital , London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P G","family":"McNally","sequence":"additional","affiliation":[{"name":"Leicester Royal Infirmary , Leicester"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2003,7,1]]},"reference":[{"key":"2023042410194799300_R1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1093\/qjmed\/92.6.319","article-title":"Substance misuse in acute general medical admissions","volume":"92","author":"Canning","year":"1999","journal-title":"Q J Med"},{"key":"2023042410194799300_R2","doi-asserted-by":"crossref","first-page":"515","DOI":"10.2169\/internalmedicine.35.515","article-title":"Metabolic alkalosis and myoclonus from antacid ingestion","volume":"35","author":"Okada","year":"1996","journal-title":"Internal Medicine"},{"key":"2023042410194799300_R3","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/S0002-9343(00)00394-6","article-title":"Baking soda toxicity","volume":"108","author":"Razzavi","year":"2000","journal-title":"Am J Med"},{"key":"2023042410194799300_R4","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0196-0644(88)80781-9","article-title":"Severe metabolic alkalosis in the emergency department","volume":"17","author":"Mennen","year":"1988","journal-title":"Ann Emerg Med"},{"key":"2023042410194799300_R5","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/S0272-6386(97)90292-4","article-title":"Hypocalcaemic tetany and metabolic alkalosis in a dialysis patient: an unusual event","volume":"30","author":"Kaye","year":"1997","journal-title":"Am J Kidney Dis"},{"key":"2023042410194799300_R6","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1046\/j.1365-201X.1996.196000.x","article-title":"Mechanism underlying changes of tetanic [Ca2+]i and force in skeletal muscle","volume":"156","author":"Westerblad","year":"1996","journal-title":"Acta Physiol Scand"},{"key":"2023042410194799300_R7","first-page":"354","article-title":"Metabolic alkalosis","volume":"46","author":"Khanna","year":"2001","journal-title":"Respiratory Care"},{"key":"2023042410194799300_R8","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1136\/bmj.283.6298.1016","article-title":"Severe metabolic alkalosis: a case report","volume":"283","author":"Javaheri","year":"1981","journal-title":"BMJ"}],"container-title":["Postgraduate Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/79\/933\/414\/50038768\/postgradmedj-79-414.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/pmj\/article-pdf\/79\/933\/414\/50038768\/postgradmedj-79-414.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T10:53:16Z","timestamp":1682333596000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/pmj\/article\/79\/933\/414\/7045573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,1]]},"references-count":8,"journal-issue":{"issue":"933","published-online":{"date-parts":[[2003,7,1]]},"published-print":{"date-parts":[[2003,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/pmj.79.933.414","relation":{},"ISSN":["0032-5473","1469-0756"],"issn-type":[{"value":"0032-5473","type":"print"},{"value":"1469-0756","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2003,7]]},"published":{"date-parts":[[2003,7,1]]}}}