{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T01:15:45Z","timestamp":1726449345494},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"937","license":[{"start":{"date-parts":[[2003,11,1]],"date-time":"2003-11-01T00:00:00Z","timestamp":1067644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The effective management of constipation in childhood requires an understanding of the ways that the physical and psychological factors interact. The early difficulty with defecation that leads to pain, fear, and refusal to use the pot or lavatory often progresses to the formation of vicious cycles of increasing faecal retention as the rectum increases in capacity and the experience of passing large, hard stools is repeated. There is increasing distress as overflow faecal incontinence compounds the problem for the older child. The medical, psychological, and surgical management strategies are reviewed together with the rationale for their use.<\/jats:p>","DOI":"10.1136\/pmj.79.937.616","type":"journal-article","created":{"date-parts":[[2003,12,4]],"date-time":"2003-12-04T00:18:09Z","timestamp":1070497089000},"page":"616-621","source":"Crossref","is-referenced-by-count":10,"title":["Management of childhood constipation"],"prefix":"10.1093","volume":"79","author":[{"given":"G","family":"Clayden","sequence":"first","affiliation":[{"name":"Guy\u2019s, King\u2019s, St Thomas\u2019 School of Medicine, Paediatrics, St Thomas\u2019 Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A S","family":"Keshtgar","sequence":"additional","affiliation":[{"name":"Guy\u2019s, King\u2019s, St Thomas\u2019 School of Medicine, Paediatrics, St Thomas\u2019 Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2003,12,3]]},"reference":[{"key":"2023042411133800800_R1","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/0016-5085(93)90896-K","article-title":"Functional constipation and outlet delay: a population based study","volume":"105","author":"Talley","year":"1993","journal-title":"Gastroenterology"},{"key":"2023042411133800800_R2","first-page":"379","article-title":"A physiological study of the pelvic floor in rectal prolapse","volume":"31","author":"Porter","year":"1962","journal-title":"Ann R Coll Surg Engl"},{"key":"2023042411133800800_R3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1136\/adc.39.204.153","article-title":"Megarectum: physiological observations","volume":"39","author":"Callaghan","year":"1964","journal-title":"Arch Dis Child"},{"key":"2023042411133800800_R4","first-page":"252","article-title":"Constipation in childhood","volume":"August","author":"Agnarsson","year":"1990","journal-title":"Maternal and Child Health"},{"key":"2023042411133800800_R5","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1136\/gut.34.10.1400","article-title":"Constipation in early childhood: patient characteristics, treatment and long term follow up","volume":"34","author":"Loening-Baucke","year":"1993","journal-title":"Gut"},{"key":"2023042411133800800_R6","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1542\/pir.8-10-299","article-title":"Constipation in children","volume":"8","author":"Fitzgerald","year":"1987","journal-title":"Pediatr Rev"},{"key":"2023042411133800800_R7","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1136\/adc.79.3.266","article-title":"Rectal biopsy in the investigation of constipation","volume":"79","author":"Ghosh","year":"1998","journal-title":"Arch Dis Child"},{"key":"2023042411133800800_R8","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/0016-5085(78)90476-6","article-title":"A familial neuronal disease presenting as intestinal pseudo-obstruction","volume":"75","author":"Schuffler","year":"1978","journal-title":"Gastroenterology"},{"key":"2023042411133800800_R9","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1399-0004.1980.tb00888.x","article-title":"Idiopathic intestinal pseudo-obstruction: a familial visceral neuropathy","volume":"18","author":"Roy","year":"1980","journal-title":"Clin Genet"},{"key":"2023042411133800800_R10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00005176-199008000-00006","article-title":"Visceral neuropathies responsible for chronic intestinal pseudo-obstruction syndrome in pediatric practice. 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