{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T21:28:35Z","timestamp":1790458115427,"version":"4.1.0"},"reference-count":10,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2022,11,30]]},"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:p>Opsoclonus\u2013myoclonus syndrome is a combination of involuntary, arrhythmic, conjugate saccadic eye movements with myoclonus. The most common cause in adults is paraneoplastic encephalitis. Rarer causes include infections such as scrub typhus, and toxins such as organophosphates and cocaine. Organophosphates are one of the common poisonings in tropical countries such as India, causing both central and peripheral nervous system manifestations. We describe a middle-aged male farmer with unexplained altered consciousness and respiratory depression. After 2\u2009days, he developed opsoclonus\u2013myoclonus, and then bronchorrhoea and bradycardia, raising suspicion of organophosphate poisoning. After we had identified a very low serum cholinesterase concentration, he disclosed having consumed organophosphates.<\/jats:p>","DOI":"10.1136\/pn-2022-003612","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T13:25:24Z","timestamp":1673011524000},"page":"243-245","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Opsoclonus\u2013myoclonus syndrome caused by organophosphate poisoning"],"prefix":"10.1136","volume":"23","author":[{"given":"Aalaya","family":"Haridas","sequence":"first","affiliation":[{"name":"General Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7694-6810","authenticated-orcid":false,"given":"Pradeep","family":"Ravi","sequence":"additional","affiliation":[{"name":"General Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,1,6]]},"reference":[{"key":"2025090410390018000_23.3.243.1","doi-asserted-by":"crossref","DOI":"10.3390\/children8110965","article-title":"Opsoclonus-Myoclonus syndrome in children and adolescents: a therapeutic challenge","volume":"8","author":"Auconi","year":"2021","journal-title":"Children"},{"key":"2025090410390018000_23.3.243.2","unstructured":"Robb EL , Baker MB . Organophosphate Toxicity. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing, 2022. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470430\/"},{"key":"2025090410390018000_23.3.243.3","unstructured":"American Academy of Ophthalmology . Opsoclonus-Myoclonus Syndrome [Internet], 2016. Available: https:\/\/www.aao.org\/disease-review\/opsoclonus-myoclonus-syndrome"},{"key":"2025090410390018000_23.3.243.4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s13365-020-00941-1","article-title":"Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature","volume":"27","author":"Emamikhah","year":"2021","journal-title":"J Neurovirol"},{"key":"2025090410390018000_23.3.243.5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1212\/WNL.43.1_Part_1.207","article-title":"Antineuronal (anti-Ri) antibodies in a patient with steroid-responsive opsoclonus-myoclonus","volume":"43","author":"Dropcho","year":"1993","journal-title":"Neurology"},{"key":"2025090410390018000_23.3.243.6","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.166"},{"key":"2025090410390018000_23.3.243.7","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2012.1173"},{"key":"2025090410390018000_23.3.243.8","doi-asserted-by":"publisher","DOI":"10.4103\/0972-5229.144017"},{"key":"2025090410390018000_23.3.243.9","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-007043"},{"key":"2025090410390018000_23.3.243.10","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520420126037"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/pn-2022-003612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T17:39:11Z","timestamp":1757007551000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/pn-2022-003612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,6]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,5,25]]},"published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1136\/pn-2022-003612"],"URL":"https:\/\/doi.org\/10.1136\/pn-2022-003612","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,6]]}}}