{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:21:31Z","timestamp":1781666491459,"version":"3.54.5"},"reference-count":10,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2023,7,16]]},"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Progressive myelopathy, urinary retention and gait problems are rare presenting features of Lyme neuroborreliosis. A 30-year-old man had 11 months of urinary retention and 3 months of spastic paraparesis. MR scans of the brain and the spinal cord showed leptomeningeal thickening with contrast enhancement. Cerebrospinal fluid showed mononuclear pleocytosis, decreased glucose, increased protein and chemokine ligand 13, with intrathecal <jats:italic>Borrelia<\/jats:italic>-specific IgM and IgG antibodies. He received 14 days of intravenous ceftriaxone followed by 14 days of oral doxycycline. Despite improvement at 6 months, he still had severe gait problems. Urinary retention in otherwise healthy people needs investigation, and Lyme neuroborreliosis is a rare cause.<\/jats:p>","DOI":"10.1136\/pn-2023-003779","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T13:20:47Z","timestamp":1690982447000},"page":"504-506","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Lyme neuroborreliosis presenting with urinary retention and spastic paraparesis"],"prefix":"10.1136","volume":"23","author":[{"given":"Lars","family":"Iversen","sequence":"first","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus Spangsberg","family":"Boesen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan Chrilles","family":"Zibrandtsen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zealand University Hospital, Roskilde, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,8,2]]},"reference":[{"key":"2025090411321221000_23.6.504.1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050216"},{"key":"2025090411321221000_23.6.504.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02862.x"},{"key":"2025090411321221000_23.6.504.3","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0022-5347(17)40231-X","article-title":"Lyme disease presenting as urinary retention","volume":"143","author":"Chancellor","year":"1990","journal-title":"J Urol"},{"key":"2025090411321221000_23.6.504.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(95)80128-6"},{"key":"2025090411321221000_23.6.504.5","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-2112-z"},{"key":"2025090411321221000_23.6.504.6","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/115.2.399"},{"key":"2025090411321221000_23.6.504.7","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70128-X"},{"key":"2025090411321221000_23.6.504.8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s12987-020-0170-5","article-title":"Chemokine Cxcl13 in serum, CSF and blood-CSF barrier function: evidence of compartment restriction","volume":"17","author":"Pilz","year":"2020","journal-title":"Fluids Barriers CNS"},{"key":"2025090411321221000_23.6.504.9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2020.116843","article-title":"Sensitivity and specificity of cerebrospinal fluid Cxcl13 for diagnosing Lyme Neuroborreliosis - a study on 1410 patients and review of the literature","volume":"414","author":"Lintner","year":"2020","journal-title":"J Neurol Sci"},{"key":"2025090411321221000_23.6.504.10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.msard.2018.12.034","article-title":"Lyme Myelopathy: case report and literature review of a rare but treatable disorder","volume":"29","author":"Kaiser","year":"2019","journal-title":"Mult Scler Relat Disord"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/pn-2023-003779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T18:32:20Z","timestamp":1757010740000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/pn-2023-003779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,2]]},"references-count":10,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,11,23]]},"published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1136\/pn-2023-003779"],"URL":"https:\/\/doi.org\/10.1136\/pn-2023-003779","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,2]]}}}