{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:17:59Z","timestamp":1793830679015,"version":"4.6.1"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2023,9,25]]},"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>Guillain-Barr\u00e9 syndrome (GBS) describes a neurological syndrome characterised by acute, areflexic paralysis, often preceded by an immune stimulating event such as infection or surgery. Spinal surgery as an inciting event is very uncommon with few reported cases. When paraparesis develops in close proximity of surgery, surgical complications should be considered, but if an asymptomatic clinical interval precedes a progressive ascending weakness this association weakens and may support an immunological mechanism. GBS after lumbar surgery is wholly unexpected and thus there are significant challenges in recognising and making the diagnosis. We report a case of fulminant GBS that progressed to loss of all motor function following elective lumbar spine surgery.<\/jats:p>","DOI":"10.1136\/pn-2023-003925","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T13:21:44Z","timestamp":1698412904000},"page":"63-65","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Locked in from fulminant GBS after lumbar spine surgery"],"prefix":"10.1136","volume":"24","author":[{"given":"Reece M","family":"Hass","sequence":"first","affiliation":[{"name":"Neurology, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9807-9172","authenticated-orcid":false,"given":"Eelco F M","family":"Wijdicks","sequence":"additional","affiliation":[{"name":"Neurology, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,10,27]]},"reference":[{"key":"2025090411350877000_24.1.63.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00517-1"},{"key":"2025090411350877000_24.1.63.2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.2.150"},{"key":"2025090411350877000_24.1.63.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2012.03730.x"},{"key":"2025090411350877000_24.1.63.4","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/ene.12565","article-title":"The incidence and triggers of adult-onset Guillain-Barr\u00e9 syndrome in southwestern Finland 2004-2013","volume":"22","author":"Sipil\u00e4","year":"2015","journal-title":"Eur J Neurol"},{"key":"2025090411350877000_24.1.63.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2016.02.003"},{"key":"2025090411350877000_24.1.63.6","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000451"},{"key":"2025090411350877000_24.1.63.7","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.clineuro.2015.05.001","article-title":"Admission neurophysiological abnormalities in Guillain-Barre syndrome: A single-Centerexperience","volume":"135","author":"Luigetti","year":"2015","journal-title":"Clinical Neurology and Neurosurgery"},{"key":"2025090411350877000_24.1.63.8","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.wneu.2019.04.239","article-title":"Postoperative Guillain-Barr\u00e9 syndrome, a neurologic complication that must not be overlooked: A literature review","volume":"128","author":"Zhong","year":"2019","journal-title":"World Neurosurg"},{"key":"2025090411350877000_24.1.63.9","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1111\/ene.15955","article-title":"Hospital-diagnosed morbidities and recent surgery as risk factors for developing Guillain-Barr\u00e9 syndrome","volume":"30","author":"Levison","year":"2023","journal-title":"Eur J Neurol"},{"key":"2025090411350877000_24.1.63.10","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.pediatrneurol.2011.03.005","article-title":"Locked-in syndrome in three children with Guillain-Barr\u00e9 syndrome","volume":"45","author":"Medici","year":"2011","journal-title":"Pediatr Neurol"},{"key":"2025090411350877000_24.1.63.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8760(00)00098-2"},{"key":"2025090411350877000_24.1.63.12","first-page":"357","article-title":"Long-term impact after fulminant Guillain-Barr\u00e9 syndrome, case report and literature review","volume":"9","author":"Roug\u00e9","year":"2016","journal-title":"Int Med Case Rep J"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/pn-2023-003925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T18:35:18Z","timestamp":1757010918000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/pn-2023-003925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,27]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1,23]]},"published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1136\/pn-2023-003925"],"URL":"https:\/\/doi.org\/10.1136\/pn-2023-003925","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,27]]}}}