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He was subsequently diagnosed with tetrodotoxin toxicity from pufferfish ingestion. He was managed supportively and made a complete recovery. Tetrodotoxicity has been hitherto considered rare outside of Southeast Asia, but rising water temperatures and human interventions have facilitated the migration of marine species containing tetrodotoxin to a wider geographical range.<\/jats:p>","DOI":"10.1136\/pn-2024-004368","type":"journal-article","created":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T13:16:47Z","timestamp":1734182207000},"page":"377-379","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Tetrodotoxin toxicity: an increasing threat"],"prefix":"10.1136","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5183-7762","authenticated-orcid":false,"given":"Emily","family":"Burton","sequence":"first","affiliation":[{"name":"Royal Adelaide Hospital, Adelaide, South Australia, Australia"},{"name":"The University of Adelaide, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair","family":"Ward","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital, Adelaide, South Australia, Australia"},{"name":"Women's and Children's Hospital Adelaide, North Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lachlan","family":"Tamlin","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaddy","family":"El-Masri","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy","family":"Goh","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital, Adelaide, South Australia, Australia"},{"name":"The University of Adelaide, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roula","family":"Ghaoui","sequence":"additional","affiliation":[{"name":"Royal Adelaide Hospital, Adelaide, South Australia, Australia"},{"name":"Department of Genetics & Molecular Pathology, SA Pathology, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5130-8628","authenticated-orcid":false,"given":"Stephen","family":"Bacchi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Flinders Medical Centre, Bedford Park, Australia"},{"name":"Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2024,12,14]]},"reference":[{"key":"2025090409183095000_25.4.377.1","doi-asserted-by":"publisher","DOI":"10.1136\/emj.15.5.334"},{"key":"2025090409183095000_25.4.377.2","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1212\/01.wnl.0000187128.80551.1b","article-title":"Captain Cook on poison fish","volume":"65","author":"Doherty","year":"2005","journal-title":"Neurology (ECronicon)"},{"key":"2025090409183095000_25.4.377.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80969-1"},{"key":"2025090409183095000_25.4.377.4","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1093\/brain\/aws225","article-title":"Neurological perspectives on voltage-gated sodium channels","volume":"135","author":"Eijkelkamp","year":"2012","journal-title":"Brain (Bacau)"},{"key":"2025090409183095000_25.4.377.5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3390\/md403143","article-title":"The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels","volume":"4","author":"Geffeney","year":"2006","journal-title":"Mar Drugs"},{"key":"2025090409183095000_25.4.377.6","unstructured":"Halstead BW . 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