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The paralysis recovered dramatically after an episode of medically induced coma, administered because of SARS-CoV-2 acute respiratory distress. A 40-year-old woman had complete recovery of FND-related arm paralysis and associated chronic pain after a deliberate overdose that led to a comatose state necessitating a brief period of ventilation. We compare these with similar recoveries in other scenarios, such as following hypnosis or extreme external stress. We discuss the potential mechanisms for recovery and the implications for FND treatment.<\/jats:p>","DOI":"10.1136\/pn-2024-004510","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T19:35:24Z","timestamp":1746646524000},"page":"562-565","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Improvement of functional paralysis following unexpected comatose states"],"prefix":"10.1136","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8802-5442","authenticated-orcid":false,"given":"Philomene Margit","family":"Klok","sequence":"first","affiliation":[{"name":"Psychiatry, Radboudumc, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marinus","family":"Vermeulen","sequence":"additional","affiliation":[{"name":"Neurology, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9829-8092","authenticated-orcid":false,"given":"Jon","family":"Stone","sequence":"additional","affiliation":[{"name":"Dept Clinical Neurosciences, University of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bastiaan R","family":"Bloem","sequence":"additional","affiliation":[{"name":"Neurology, Radboudumc, Nijmegen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"2025111304551240000_25.6.562.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00422-1"},{"key":"2025111304551240000_25.6.562.2","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.o64","article-title":"Diagnosis and management of functional neurological disorder","volume":"376","author":"Aybek","year":"2022","journal-title":"BMJ"},{"key":"2025111304551240000_25.6.562.3","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S0140-6736(01)48807-6","article-title":"THE TREATMENT OF SOME COMMON WAR NEUROSES","volume":"189","author":"Adrian","year":"1917","journal-title":"The Lancet"},{"key":"2025111304551240000_25.6.562.4","doi-asserted-by":"crossref","first-page":"436","DOI":"10.4997\/jrcpe.2020.420","article-title":"Hurst Rehabilitated: the treatment of functional motor disorders by Arthur Hurst during the First World War","volume":"50","author":"Jones","year":"2020","journal-title":"J R Coll Physicians Edinb"},{"key":"2025111304551240000_25.6.562.5","first-page":"231","article-title":"Phenomenology and psychopathology related to psychogenic movement disorders","volume":"65","author":"Williams","year":"1995","journal-title":"Adv Neurol"},{"key":"2025111304551240000_25.6.562.6","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1002\/mds.21467","article-title":"Acupuncture for psychogenic movement disorders: treatment or diagnostic tool?","volume":"22","author":"Van Nuenen","year":"2007","journal-title":"Mov Disord"},{"key":"2025111304551240000_25.6.562.7","unstructured":"Middendorp P . 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