{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T15:16:41Z","timestamp":1774019801067,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2025,6,30]]},"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    A man in his 30s from South Asia presented with progressive neck pain, occipital headache and right-sided tongue deviation (occipital condyle syndrome). Initial imaging identified a destructive skull base lesion involving the right clivus, occipital condyle and C1 vertebra with compression of the hypoglossal nerve, raising concerns for malignancy. Concurrent necrotic mediastinal lymphadenopathy prompted endobronchial ultrasound-guided biopsy, which confirmed necrotising granulomatous lymphadenitis with\n                    <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n                    complex DNA. Quadruple antituberculous therapy and adjunctive corticosteroids gave significant clinical and radiological improvement at 6 months. This case highlights the importance of considering tuberculosis in the differential diagnosis of destructive skull base lesions even in non-endemic regions and in patients with previously negative TB screening.\n                  <\/jats:p>","DOI":"10.1136\/pn-2025-004705","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T21:40:26Z","timestamp":1752183626000},"page":"43-46","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Occipital condyle syndrome: a rare manifestation of skull base tuberculosis"],"prefix":"10.1136","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1073-5825","authenticated-orcid":false,"given":"Joshua J","family":"Hon","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasundhara","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerda","family":"Reischer","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alistair","family":"Lawrence","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6373-1500","authenticated-orcid":false,"given":"Joe","family":"M Das","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"2026031908251004000_26.1.43.1","unstructured":"Organization WH . Global tuberculosis report 2024. Geneva, 2024."},{"key":"2026031908251004000_26.1.43.2","doi-asserted-by":"crossref","unstructured":"Leonard JM . Central Nervous System Tuberculosis. Microbiol Spectr 2017;5. doi:10.1128\/microbiolspec.tnmi7-0044-2017","DOI":"10.1128\/microbiolspec.TNMI7-0044-2017"},{"key":"2026031908251004000_26.1.43.3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00042-07"},{"key":"2026031908251004000_26.1.43.4","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2021200046"},{"key":"2026031908251004000_26.1.43.5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2002.02032.x"},{"key":"2026031908251004000_26.1.43.6","first-page":"MD01","article-title":"Occipital condyle syndrome in a young male: a rare presentation of cranio-vertebral tuberculosis","volume":"8","author":"Neera","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"2026031908251004000_26.1.43.7","doi-asserted-by":"crossref","first-page":"551","DOI":"10.4103\/0028-3886.227324","article-title":"Occipital condyle syndrome due to tuberculosis: An uncommon cause unearthed by an unconventional approach","volume":"66","author":"Krishnan","year":"2018","journal-title":"Neurol India"},{"key":"2026031908251004000_26.1.43.8","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(93)90079-S"},{"key":"2026031908251004000_26.1.43.9","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s13244-018-0653-y","article-title":"Spectrum of lytic lesions of the skull: a pictorial essay","volume":"9","author":"Ugga","year":"2018","journal-title":"Insights Imaging"},{"key":"2026031908251004000_26.1.43.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2009.06.011"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/pn-2025-004705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T13:52:25Z","timestamp":1774014745000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/pn-2025-004705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,10]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,13]]},"published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1136\/pn-2025-004705"],"URL":"https:\/\/doi.org\/10.1136\/pn-2025-004705","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,10]]}}}