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This can significantly influence the clinical consultation and the patient\u2019s neurological presentation and management. We offer practical guidance for neurologists to understand personality-related presentations better, along with clinical pointers to distinguish lifelong traits from changes secondary to neurological disease and advice on managing structured consultations with empathy. Recognising this interplay between personality and neurological care will support neurologists to deliver targeted, compassionate and higher quality care, improving patient engagement, safety and overall therapeutic experience.<\/jats:p>","DOI":"10.1136\/pn-2026-005213","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T17:20:22Z","timestamp":1786641622000},"page":"pn-2026-005213","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Personality disorders: what the neurologist should know"],"prefix":"10.1136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5661-0719","authenticated-orcid":false,"given":"Lily","family":"Farakish","sequence":"first","affiliation":[{"name":"Institute of Population Health, Primary Care and Mental Health, University of Liverpool, Liverpool, UK"},{"name":"Mental Health Research for Innovation Centre (M-RIC), Mersey Care NHS Foundation Trust, Liverpool, UK"},{"name":"Liverpool Interdisciplinary Neuroscience Centre (LINC), University of Liverpool, Liverpool, UK"},{"name":"Civic Health Innovation Labs, University of Liverpool, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfia","family":"Arun","sequence":"additional","affiliation":[{"name":"The Walton Centre NHS Foundation Trust, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Browne","sequence":"additional","affiliation":[{"name":"Mental Health Research for Innovation Centre (M-RIC), Mersey Care NHS Foundation Trust, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tashi","family":"Thornley","sequence":"additional","affiliation":[{"name":"Mental Health Research for Innovation Centre (M-RIC), Mersey Care NHS Foundation Trust, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9433-5340","authenticated-orcid":false,"given":"Dan W","family":"Joyce","sequence":"additional","affiliation":[{"name":"Institute of Population Health, Primary Care and Mental Health, University of Liverpool, Liverpool, UK"},{"name":"Mental Health Research for Innovation Centre (M-RIC), Mersey Care NHS Foundation Trust, Liverpool, UK"},{"name":"Liverpool Interdisciplinary Neuroscience Centre (LINC), University of Liverpool, Liverpool, UK"},{"name":"Civic Health Innovation Labs, University of Liverpool, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9588-2944","authenticated-orcid":false,"given":"Gashirai K","family":"Mbizvo","sequence":"additional","affiliation":[{"name":"Liverpool Interdisciplinary Neuroscience Centre (LINC), University of Liverpool, Liverpool, UK"},{"name":"The Walton Centre NHS Foundation Trust, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"2026081310201729000_pn-2026-005213v1.1","doi-asserted-by":"crossref","first-page":"110482","DOI":"10.1016\/j.neuropharm.2025.110482","article-title":"Personality disorders: A preface","volume":"274","author":"More","year":"2025","journal-title":"Neuropharmacology"},{"key":"2026081310201729000_pn-2026-005213v1.2","doi-asserted-by":"crossref","unstructured":"Lock J , Yang M , Tyrer P . 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