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Important investigations include vital capacity, mouth pressures, arterial blood gases, chest <jats:italic>x<\/jats:italic> ray and sometimes overnight respiratory monitoring. Patients with Guillain-Barr\u00e9 and other acute conditions may require short-term ventilatory support in the intensive care unit. Patients with some chronic disorders, such as motor neuron disease and Duchenne dystrophy, can be successfully treated with non-invasive ventilation, usually in collaboration with a respiratory physician. New-onset weakness of limb and respiratory muscles in the intensive care unit is usually due to critical illness myopathy or critical illness polyneuropathy, and treatment is supportive.<\/jats:p>","DOI":"10.1136\/pn.2008.152611","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T14:54:08Z","timestamp":1217256848000},"page":"229-237","source":"Crossref","is-referenced-by-count":74,"title":["Neuromuscular disease and respiratory failure"],"prefix":"10.1136","volume":"8","author":[{"given":"D","family":"Hutchinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Whyte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2008,7,21]]},"reference":[{"key":"2025090409234042000_8.4.229.1","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0022-5223(19)38936-6","article-title":"Unexplained diaphragmatic paralysis: a harbinger of malignant disease?","volume":"84","author":"Piehler","year":"1982","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025090409234042000_8.4.229.2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200301000-00044"},{"key":"2025090409234042000_8.4.229.3","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.58.6.893"},{"key":"2025090409234042000_8.4.229.4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70603-2"},{"key":"2025090409234042000_8.4.229.5","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70326-4"},{"key":"2025090409234042000_8.4.229.6","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000180362.90078.dc"},{"key":"2025090409234042000_8.4.229.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(02)00140-2"},{"key":"2025090409234042000_8.4.229.8","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20283"},{"key":"2025090409234042000_8.4.229.9","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1378\/chest.101.3.824","article-title":"Respiratory failure revealing mitochondrial myopathy in adults.","volume":"101","author":"Cros","year":"1992","journal-title":"Chest"},{"key":"2025090409234042000_8.4.229.10","first-page":"406","article-title":"Acid maltase deficiency: clinical and laboratory features of adult-onset cases.","volume":"114","author":"Read","year":"2001","journal-title":"N Z Med J"},{"key":"2025090409234042000_8.4.229.11","first-page":"189","article-title":"Severe respiratory muscle weakness related to long-term colchicine therapy.","volume":"49","author":"Tanios","year":"2004","journal-title":"Respir Care"},{"key":"2025090409234042000_8.4.229.12","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1016"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/pn.2008.152611","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T16:23:50Z","timestamp":1757003030000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/pn.2008.152611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,21]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2008,7,21]]},"published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1136\/pn.2008.152611"],"URL":"https:\/\/doi.org\/10.1136\/pn.2008.152611","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,21]]}}}